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Aliases for ZEB2-AS1 Gene

Subcategory (RNA class) for ZEB2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for ZEB2-AS1 Gene

  • ZEB2 Antisense RNA 1 2 3 5
  • ZEB2 Antisense RNA 1 (Non-Protein Coding) 2 3
  • ZEB2 Natural Antisense Transcript 2 3
  • ZEB2 Antisense RNA (Non-Protein Coding) 2
  • ZEB2NAT 3
  • ZEB2-AS 3
  • ZEB2AS 3

External Ids for ZEB2-AS1 Gene

Previous HGNC Symbols for ZEB2-AS1 Gene

  • ZEB2AS
  • ZEB2-AS

Previous GeneCards Identifiers for ZEB2-AS1 Gene

  • GC02U902264
  • GC02P145277

Summaries for ZEB2-AS1 Gene

Entrez Gene Summary for ZEB2-AS1 Gene

  • This gene produces a spliced long non-coding RNA which is a natural antisense transcript corresponding to the 5' UTR of zinc finger E-box binding homeobox 2 (ZEB2). It is thought that this transcript may be involved in the regulation of ZEB2 expression, and may play a role in the progression of bladder cancer. [provided by RefSeq, Aug 2015]

GeneCards Summary for ZEB2-AS1 Gene

ZEB2-AS1 (ZEB2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Gene Wiki entry for ZEB2-AS1 Gene

Additional gene information for ZEB2-AS1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZEB2-AS1 Gene

Genomics for ZEB2-AS1 Gene

GeneHancer (GH) Regulatory Elements for ZEB2-AS1 Gene

Promoters and enhancers for ZEB2-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I144451 Promoter/Enhancer 2.6 UCNEbase FANTOM5 Ensembl ENCODE dbSUPER 11.4 -60.5 -60544 12 PKNOX1 ATF1 ARNT FEZF1 ZNF2 IRF4 TCF12 ZNF121 ZNF213 ZNF548 ZEB2 ZEB2-AS1 ENSG00000231758 GTDC1 ENSG00000283118 GC02P144494
GH02I144579 Enhancer 2.2 VISTA UCNEbase Ensembl ENCODE dbSUPER 11.4 +64.1 64051 4.9 HDGF PKNOX1 SMAD1 ARNT SIN3A YBX1 POLR2B ZNF766 E2F8 FOS ZEB2 ZEB2-AS1 GC02P144567 TEX41
GH02I144469 Enhancer 1.6 UCNEbase Ensembl ENCODE dbSUPER 11.1 -47.8 -47760 3.4 PKNOX1 FEZF1 ZNF2 RELA FOXM1 CTBP1 ZNF213 POLR2A GLI2 ZSCAN5C ZEB2 ZEB2-AS1 GC02P144494 ENSG00000283118
GH02I144473 Enhancer 1.4 UCNEbase Ensembl ENCODE dbSUPER 11.7 -42.2 -42151 5.3 PKNOX1 TEAD4 TAL1 CEBPB CBFA2T3 CEBPG FEZF1 TCF12 PRDM6 POLR2A ZEB2 ZEB2-AS1 GC02P144494 ENSG00000283118
GH02I144378 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 10.6 -137.9 -137933 3.7 ZNF639 GTF2E2 CEBPG DPF2 ATF2 ZNF395 ZNF592 SMARCA4 POLR2A ZKSCAN8 GTDC1 ZEB2 ZEB2-AS1 LOC101928386 GC02M144385
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZEB2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZEB2-AS1 Gene

Genomic Locations for ZEB2-AS1 Gene
chr2:144,518,097-144,521,477
(GRCh38/hg38)
Size:
3,381 bases
Orientation:
Plus strand
chr2:145,275,664-145,279,058
(GRCh37/hg19)

Genomic View for ZEB2-AS1 Gene

Genes around ZEB2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZEB2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZEB2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZEB2-AS1 Gene

Proteins for ZEB2-AS1 Gene

Post-translational modifications for ZEB2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZEB2-AS1 Gene

Domains & Families for ZEB2-AS1 Gene

Gene Families for ZEB2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZEB2-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZEB2-AS1 Gene

Function for ZEB2-AS1 Gene

Phenotypes From GWAS Catalog for ZEB2-AS1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZEB2-AS1 Gene

Localization for ZEB2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ZEB2-AS1 Gene

Pathways & Interactions for ZEB2-AS1 Gene

SuperPathways for ZEB2-AS1 Gene

No Data Available

Interacting Proteins for ZEB2-AS1 Gene

Gene Ontology (GO) - Biological Process for ZEB2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZEB2-AS1 Gene

Drugs & Compounds for ZEB2-AS1 Gene

No Compound Related Data Available

Transcripts for ZEB2-AS1 Gene

mRNA/cDNA for ZEB2-AS1 Gene

(1) Additional mRNA sequences :
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZEB2-AS1 Gene

ZEB2 antisense RNA 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZEB2-AS1 Gene

No ASD Table

Relevant External Links for ZEB2-AS1 Gene

GeneLoc Exon Structure for
ZEB2-AS1
ECgene alternative splicing isoforms for
ZEB2-AS1

Expression for ZEB2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZEB2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ZEB2-AS1 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x6.4).

SOURCE GeneReport for Unigene cluster for ZEB2-AS1 Gene:

Hs.560789
genes like me logo Genes that share expression patterns with ZEB2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZEB2-AS1 Gene

Orthologs for ZEB2-AS1 Gene

Evolution for ZEB2-AS1 Gene

ENSEMBL:
Gene Tree for ZEB2-AS1 (if available)
TreeFam:
Gene Tree for ZEB2-AS1 (if available)

No data available for Orthologs for ZEB2-AS1 Gene

Paralogs for ZEB2-AS1 Gene

No data available for Paralogs for ZEB2-AS1 Gene

Variants for ZEB2-AS1 Gene

Sequence variations from dbSNP and Humsavar for ZEB2-AS1 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs146048066 benign, Mowat-Wilson syndrome 144,520,357(+) A/G intron_variant
rs910157741 uncertain-significance, Mowat-Wilson syndrome 144,520,074(+) A/G non_coding_transcript_variant
rs1057521945 likely-benign, not specified 144,519,931(+) A/G intron_variant
rs1000092738 -- 144,520,455(+) T/C intron_variant
rs1000430932 -- 144,519,468(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZEB2-AS1 Gene

Variant ID Type Subtype PubMed ID
esv3592768 CNV loss 21293372

Additional Variant Information for ZEB2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZEB2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZEB2-AS1 Gene

Disorders for ZEB2-AS1 Gene

Additional Disease Information for ZEB2-AS1

No disorders were found for ZEB2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZEB2-AS1 Gene

Publications for ZEB2-AS1 Gene

  1. TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT. (PMID: 26152796) Zhuang J … Guo H (Scientific reports 2015) 2 3 58
  2. A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. (PMID: 18347095) Beltran M … de Herreros AG (Genes & development 2008) 2 3 58
  3. Downregulation of ZEB2-AS1 decreased tumor growth and metastasis in hepatocellular carcinoma. (PMID: 27748842) Lan T … Yuan Y (Molecular medicine reports 2016) 3 58

Products for ZEB2-AS1 Gene

Sources for ZEB2-AS1 Gene

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