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Aliases for ZEB1-AS1 Gene

Subcategory (RNA class) for ZEB1-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for ZEB1-AS1 Gene

  • ZEB1 Antisense RNA 1 2 3 5
  • ZEB1 Antisense RNA 1 (Non-Protein Coding) 2

External Ids for ZEB1-AS1 Gene

Previous GeneCards Identifiers for ZEB1-AS1 Gene

  • GC10M031606
  • GC10M031495

Summaries for ZEB1-AS1 Gene

Entrez Gene Summary for ZEB1-AS1 Gene

  • This locus produces long non-coding RNA that is transcribed from a shared bi-directional promoter with zinc finger E-box binding homeobox 1 (ZEB1). This transcript binds lysine methyltransferase 2A and promotes histone modifications that are thought to promote expression of ZEB1. Expression of this gene is correlated with tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

GeneCards Summary for ZEB1-AS1 Gene

ZEB1-AS1 (ZEB1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for ZEB1-AS1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZEB1-AS1 Gene

Genomics for ZEB1-AS1 Gene

GeneHancer (GH) Regulatory Elements for ZEB1-AS1 Gene

Promoters and enhancers for ZEB1-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I031316 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 560.9 +0.4 351 6.2 HDGF PKNOX1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 YY1 ZEB1-AS1 ZEB1 MTPAP ENSG00000226842 SPTLC1P1
GH10I031925 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.5 -608.0 -608030 5.8 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ARHGAP12 KIF5B ENSG00000226842 EPC1 ZEB1-AS1 HMGB1P7
GH10I030549 Enhancer 0.9 Ensembl dbSUPER 19.1 +771.2 771233 0.8 ZFP64 ZNF140 ZNF266 ZNF697 ZNF213 ZNF547 ZNF433 ZBTB11 ZC3H11A ZBTB8A MTPAP ZEB1-AS1 MAP3K8 DDX10P1 ENSG00000228800 LOC105376478
GH10I030421 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.5 +896.6 896614 3.9 ATF1 MLX ARID4B IRF4 ETS1 ZNF766 FOS CAVIN1 SP5 NFYC MAP3K8 ZEB1-AS1 CCND3P1
GH10I032148 Enhancer 1.3 Ensembl ENCODE dbSUPER 12.8 -830.1 -830052 3.6 PKNOX1 ATF1 FEZF1 ZNF2 IRF4 BRCA1 FOS ATF7 RUNX3 ZNF214 KIF5B ZEB1-AS1 RNU7-22P ENSG00000206660 ENSG00000234811
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZEB1-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZEB1-AS1 Gene

Genomic Locations for ZEB1-AS1 Gene
chr10:31,206,278-31,320,447
(GRCh38/hg38)
Size:
114,170 bases
Orientation:
Minus strand
chr10:31,495,207-31,609,376
(GRCh37/hg19)

Genomic View for ZEB1-AS1 Gene

Genes around ZEB1-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZEB1-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZEB1-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZEB1-AS1 Gene

Proteins for ZEB1-AS1 Gene

Post-translational modifications for ZEB1-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZEB1-AS1 Gene

Domains & Families for ZEB1-AS1 Gene

Gene Families for ZEB1-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZEB1-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZEB1-AS1 Gene

Function for ZEB1-AS1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZEB1-AS1 Gene

Localization for ZEB1-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ZEB1-AS1 Gene

Pathways & Interactions for ZEB1-AS1 Gene

SuperPathways for ZEB1-AS1 Gene

No Data Available

Interacting Proteins for ZEB1-AS1 Gene

Gene Ontology (GO) - Biological Process for ZEB1-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZEB1-AS1 Gene

Drugs & Compounds for ZEB1-AS1 Gene

No Compound Related Data Available

Transcripts for ZEB1-AS1 Gene

mRNA/cDNA for ZEB1-AS1 Gene

(4) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZEB1-AS1 Gene

ZEB1 antisense RNA 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZEB1-AS1 Gene

No ASD Table

Relevant External Links for ZEB1-AS1 Gene

GeneLoc Exon Structure for
ZEB1-AS1
ECgene alternative splicing isoforms for
ZEB1-AS1

Expression for ZEB1-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZEB1-AS1 Gene

SOURCE GeneReport for Unigene cluster for ZEB1-AS1 Gene:

Hs.372654
genes like me logo Genes that share expression patterns with ZEB1-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZEB1-AS1 Gene

Orthologs for ZEB1-AS1 Gene

Evolution for ZEB1-AS1 Gene

ENSEMBL:
Gene Tree for ZEB1-AS1 (if available)
TreeFam:
Gene Tree for ZEB1-AS1 (if available)

No data available for Orthologs for ZEB1-AS1 Gene

Paralogs for ZEB1-AS1 Gene

No data available for Paralogs for ZEB1-AS1 Gene

Variants for ZEB1-AS1 Gene

Sequence variations from dbSNP and Humsavar for ZEB1-AS1 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000835788 -- 31,318,383(-) G/T non_coding_transcript_variant
rs1001289274 -- 31,318,222(-) G/C non_coding_transcript_variant
rs1001663096 -- 31,317,546(-) T/C non_coding_transcript_variant
rs1001715346 -- 31,317,262(-) G/A/T non_coding_transcript_variant
rs1001786358 -- 31,317,872(-) T/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZEB1-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv831824 CNV loss 17160897

Additional Variant Information for ZEB1-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZEB1-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZEB1-AS1 Gene

Disorders for ZEB1-AS1 Gene

Additional Disease Information for ZEB1-AS1

No disorders were found for ZEB1-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZEB1-AS1 Gene

Publications for ZEB1-AS1 Gene

  1. Interplay Between Long Noncoding RNA ZEB1-AS1 and miR-200s Regulates Osteosarcoma Cell Proliferation and Migration. (PMID: 28075045) Liu C … Wang H (Journal of cellular biochemistry 2017) 2 3 58
  2. Long noncoding RNA ZEB1-AS1 acts as an oncogene in osteosarcoma by epigenetically activating ZEB1. (PMID: 27829995) Liu C … Lin J (American journal of translational research 2016) 2 3 58
  3. Expression of long non-coding RNA ZEB1-AS1 in esophageal squamous cell carcinoma and its correlation with tumor progression and patient survival. (PMID: 26617942) Wang YL … Wang ZM (International journal of clinical and experimental pathology 2015) 2 3 58
  4. Increased expression of ZEB1-AS1 correlates with higher histopathological grade and promotes tumorigenesis in bladder cancer. (PMID: 28445936) Lin J … Huang W (Oncotarget 2017) 3 58
  5. High expression of long non-coding RNA ZEB1-AS1 promotes colorectal cancer cell proliferation partially by suppressing p15 expression. (PMID: 28618933) Gong H … Zhu J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58

Products for ZEB1-AS1 Gene

Sources for ZEB1-AS1 Gene

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