Free for academic non-profit institutions. Other users need a Commercial license
ZDHHC18 (Zinc Finger DHHC-Type Palmitoyltransferase 18) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein-cysteine S-palmitoyltransferase activity and palmitoyltransferase activity. An important paralog of this gene is ZDHHC14.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016409 | palmitoyltransferase activity | IEA,IDA | 23034182 |
GO:0016740 | transferase activity | IEA | -- |
GO:0016746 | transferase activity, transferring acyl groups | IEA | -- |
GO:0019706 | protein-cysteine S-palmitoyltransferase activity | IEA,IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005783 | endoplasmic reticulum | IBA | 21873635 |
GO:0005794 | Golgi apparatus | IBA,IDA | 16647879 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006612 | protein targeting to membrane | IBA | 21873635 |
GO:0018230 | peptidyl-L-cysteine S-palmitoylation | IBA | 21873635 |
GO:0018345 | protein palmitoylation | IDA | 23034182 |
GO:0034613 | cellular protein localization | IEA | -- |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Coenzyme A | Investigational | Nutra | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
hexadecanoyl-CoA |
|
|
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZDHHC18 30 |
|
||
Dog (Canis familiaris) |
Mammalia | ZDHHC18 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Zdhhc18 30 17 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ZDHHC18 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Zdhhc18 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | ZDHHC18 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | ZDHHC18 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | ZDHHC18 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | ZDHHC18 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | zdhhc18b 31 |
|
OneToOne | |
zdhhc18a 30 |
|
||||
Dr.9165 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005111 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | app 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | dhhc-2 31 |
|
OneToMany | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT5G50020 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os01g0868200 30 |
|
||
Os.17295 30 |
|
||||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.3762 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1000012 | CNV | gain | 25217958 |
nsv834524 | CNV | gain+loss | 17160897 |
No disorders were found for ZDHHC18 Gene.