Aliases for ZDHHC16 Gene
External Ids for ZDHHC16 Gene
Previous GeneCards Identifiers for ZDHHC16 Gene
GeneCards Summary for ZDHHC16 Gene
ZDHHC16 (Zinc Finger DHHC-Type Palmitoyltransferase 16) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein-cysteine S-palmitoyltransferase activity and palmitoyltransferase activity.
UniProtKB/Swiss-Prot Summary for ZDHHC16 Gene
Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 (PubMed:28826475). Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function (PubMed:28826475). May play a role in DNA damage response (By similarity). May be involved in apoptosis regulation (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity).