Aliases for ZDHHC1 Gene
External Ids for ZDHHC1 Gene
Previous HGNC Symbols for ZDHHC1 Gene
Previous GeneCards Identifiers for ZDHHC1 Gene
GeneCards Summary for ZDHHC1 Gene
ZDHHC1 (Zinc Finger DHHC-Type Containing 1) is a Protein Coding gene. Diseases associated with ZDHHC1 include Phencyclidine Abuse. Gene Ontology (GO) annotations related to this gene include protein-cysteine S-palmitoyltransferase activity and palmitoyltransferase activity. An important paralog of this gene is ZDHHC11B.
UniProtKB/Swiss-Prot Summary for ZDHHC1 Gene
Has a palmitoyltransferase activity and palmitoylates NCDN thereby regulating its association with endosome membranes.
Could also be involved in DNA virus-triggered and CGAS-mediated innate immune response through the regulation of MITA activation by cGAMP (PubMed:25299331). The function in innate immune response is probably independent of the palmitoyltransferase activity (PubMed:25299331).