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ZDHHC1 (Zinc Finger DHHC-Type Containing 1) is a Protein Coding gene. Diseases associated with ZDHHC1 include Phencyclidine Abuse. Gene Ontology (GO) annotations related to this gene include protein-cysteine S-palmitoyltransferase activity and palmitoyltransferase activity. An important paralog of this gene is ZDHHC11B.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003677 | DNA binding | NAS | 10395086 |
GO:0005515 | protein binding | IPI | 25299331 |
GO:0016409 | palmitoyltransferase activity | IDA | 23034182 |
GO:0016740 | transferase activity | IEA | -- |
GO:0016746 | transferase activity, transferring acyl groups | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005783 | endoplasmic reticulum | IBA,IDA | 16647879 |
GO:0005789 | endoplasmic reticulum membrane | IDA | 25299331 |
GO:0005794 | Golgi apparatus | IBA,IDA | 25299331 |
GO:0010008 | endosome membrane | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002230 | positive regulation of defense response to virus by host | IEA,IMP | 25299331 |
GO:0006612 | protein targeting to membrane | IBA | 21873635 |
GO:0018230 | peptidyl-L-cysteine S-palmitoylation | IEA,IBA | 21873635 |
GO:0018345 | protein palmitoylation | IEA,IDA | 23034182 |
GO:0032461 | positive regulation of protein oligomerization | IEA | -- |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Coenzyme A | Investigational | Nutra | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
hexadecanoyl-CoA |
|
|
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15a | · | 15b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||||||||||||||||
SP4: | |||||||||||||||||||||||||||||||||||||||||
SP5: | - | ||||||||||||||||||||||||||||||||||||||||
SP6: | - |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZDHHC1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ZDHHC1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Zdhhc1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Zdhhc1 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Cow (Bos Taurus) |
Mammalia | ZDHHC1 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | ZDHHC1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | ZDHHC1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | ZDHHC1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | zdhhc1 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC562614 30 |
|
||
ZDHHC1 31 |
|
OneToOne | |||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG17075 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | dhhc-11 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ERF2 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10560 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
790708 | Benign: not provided | 67,406,302(-) | C/T | SYNONYMOUS_VARIANT | |
rs34229857 | - | p.Arg124Gln |
Disorder | Aliases | PubMed IDs |
---|---|---|
phencyclidine abuse |
|
|