Aliases for ZC3H12D Gene
External Ids for ZC3H12D Gene
Previous HGNC Symbols for ZC3H12D Gene
Previous GeneCards Identifiers for ZC3H12D Gene
GeneCards Summary for ZC3H12D Gene
ZC3H12D (Zinc Finger CCCH-Type Containing 12D) is a Protein Coding gene. Diseases associated with ZC3H12D include Follicular Lymphoma and Lymphoma. Gene Ontology (GO) annotations related to this gene include endonuclease activity. An important paralog of this gene is ZC3H12A.
UniProtKB/Swiss-Prot Summary for ZC3H12D Gene
May regulate cell growth likely by suppressing RB1 phosphorylation (PubMed:19531561). May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560). Serve as a tumor suppressor in certain leukemia cells (PubMed:17210687). Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (PubMed:19531561).