Aliases for ZBTB32 Gene
External Ids for ZBTB32 Gene
Previous GeneCards Identifiers for ZBTB32 Gene
GeneCards Summary for ZBTB32 Gene
ZBTB32 (Zinc Finger And BTB Domain Containing 32) is a Protein Coding gene. Diseases associated with ZBTB32 include Oral Tuberculosis and Lymph Node Tuberculosis. Among its related pathways are Telomere C-strand (Lagging Strand) Synthesis and Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription corepressor activity. An important paralog of this gene is ZBTB16.
UniProtKB/Swiss-Prot Summary for ZBTB32 Gene
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity).