Aliases for ZBTB32 Gene
External Ids for ZBTB32 Gene
Previous GeneCards Identifiers for ZBTB32 Gene
GeneCards Summary for ZBTB32 Gene
ZBTB32 (Zinc Finger And BTB Domain Containing 32) is a Protein Coding gene. Diseases associated with ZBTB32 include Fanconi Anemia, Complementation Group A and Gastroduodenitis. Among its related pathways are Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template and Telomere C-strand (Lagging Strand) Synthesis. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription corepressor activity. An important paralog of this gene is ZBTB16.
UniProtKB/Swiss-Prot Summary for ZBTB32 Gene
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity).