Aliases for ZBTB26 Gene
Aliases for ZBTB26 Gene
External Ids for ZBTB26 Gene
- HGNC: 23383
- Entrez Gene: 57684
- Ensembl: ENSG00000171448
- UniProtKB: Q9HCK0
Previous HGNC Symbols for ZBTB26 Gene
- ZNF481
Previous GeneCards Identifiers for ZBTB26 Gene
- GC09M121057
- GC09M122759
- GC09M124717
- GC09M125677
- GC09M095295
Summaries for ZBTB26 Gene
GeneCards Summary for ZBTB26 Gene
ZBTB26 (Zinc Finger And BTB Domain Containing 26) is a Protein Coding gene. An important paralog of this gene is ZBTB6.
UniProtKB/Swiss-Prot for ZBTB26 Gene
-
May be involved in transcriptional regulation.
Additional gene information for ZBTB26 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB26 Gene
Genomics for ZBTB26 Gene
GeneHancer (GH) Regulatory Elements for ZBTB26 Gene
Promoters and enhancers for ZBTB26 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZBTB26 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ZBTB26 gene promoter:
-
- Hand1
- E47
- HEN1
- Pax-5
- HNF-3beta
- SRY
- GATA-1
- CUTL1
- AP-2alpha
- AP-2alphaA
Regulatory Element Products
Genomic Locations for ZBTB26 Gene
Genomic Locations for ZBTB26 Gene
- chr9:122,915,566-122,931,551
- (GRCh38/hg38)
- Size:
- 15,986 bases
- Orientation:
- Minus strand
- chr9:125,677,845-125,693,779
- (GRCh37/hg19)
- Size:
- 15,935 bases
- Orientation:
- Minus strand
Genomic View for ZBTB26 Gene
Genes around ZBTB26 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q33.2 by Entrez Gene
- 9q33.2 by HGNC
- 9q33.2 by Ensembl
ZBTB26 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZBTB26 Gene
Proteins for ZBTB26 Gene
-
Protein details for ZBTB26 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HCK0-ZBT26_HUMAN
- Recommended name:
- Zinc finger and BTB domain-containing protein 26
- Protein Accession:
- Q9HCK0
- B3KQ53
- Q8WTR1
Protein attributes for ZBTB26 Gene
- Size:
- 441 amino acids
- Molecular mass:
- 49953 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAB13398.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ZBTB26 Gene
Post-translational modifications for ZBTB26 Gene
Other Protein References for ZBTB26 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ZBTB26
- Invitrogen Antibodies for ZBTB26
- GeneTex ZBTB26 Antibody for ZBTB26
-
Boster Bio Antibodies for ZBTB26
Protein Products
-
OriGene Purified Proteins for ZBTB26
- Search Origene for MassSpec and Protein Over-expression Lysates for ZBTB26
- Origene Custom Protein Services for ZBTB26
- antibodies-online: Search results for 2 available ZBTB26 Proteins ranked by validation data
- Compare Top ZBTB26 Proteins
-
Quality Products:
- Search GeneTex for Proteins for ZBTB26
-
Abcam proteins for ZBTB26
Assay Products
No data available for DME Specific Peptides for ZBTB26 Gene
Domains & Families for ZBTB26 Gene
Gene Families for ZBTB26 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZBTB26 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZBTB26 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for ZBTB26 Gene
Function for ZBTB26 Gene
Molecular function for ZBTB26 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in transcriptional regulation.
Phenotypes From GWAS Catalog for ZBTB26 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | ISA | -- |
| GO:0003674 | molecular_function | ND | -- |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for ZBTB26 Gene
- GenomeRNAi human phenotypes for ZBTB26:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ZBTB26
-
CRISPR Products
-
OriGene CRISPR knockouts for ZBTB26
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZBTB26
- genomics-online: gRNA clones - Search results for available ZBTB26 gene related products
- Applied Biological Materials CRISPR for ZBTB26
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZBTB26
miRNA for ZBTB26 Gene
- miRTarBase miRNAs that target ZBTB26
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZBTB26
- Browse OriGene Inhibitory RNA Products For ZBTB26
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- genomics-online: shRNA clones - Search results for available ZBTB26 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ZBTB26
- VectorBuilder custom plasmid, inducible vectors for ZBTB26
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZBTB26
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZBTB26
- genomics-online: cdna clones - Search results for available ZBTB26 gene related products
- orf clones - Search results for available ZBTB26 gene related products
- Applied Biological Materials Clones for ZBTB26
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ZBTB26
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBTB26 Gene
Localization for ZBTB26 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZBTB26 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
| GO:0005634 | nucleus | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZBTB26 Gene
Pathways & Interactions for ZBTB26 Gene
No Data Available
Interacting Proteins for ZBTB26 Gene
Selected Interacting proteins:
Q9HCK0-ZBT26_HUMAN
ENSP00000362758
for ZBTB26 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ZBTB26
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for ZBTB26 Gene
Transcripts for ZBTB26 Gene
mRNA/cDNA for ZBTB26 Gene
- (3) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (74) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000373656 4443 bps (uc004bnk.4)
- ENST00000373654 2047 bps (uc004bnj.4)
Unigene Clusters for ZBTB26 Gene
- Zinc finger and BTB domain containing 26:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ZBTB26
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZBTB26
- genomics-online: gRNA clones - Search results for available ZBTB26 gene related products
- Applied Biological Materials CRISPR for ZBTB26
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZBTB26
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZBTB26
- Browse OriGene Inhibitory RNA Products For ZBTB26
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZBTB26
- genomics-online: shRNA clones - Search results for available ZBTB26 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ZBTB26
- VectorBuilder custom plasmid, inducible vectors for ZBTB26
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZBTB26
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZBTB26
- genomics-online: cdna clones - Search results for available ZBTB26 gene related products
- orf clones - Search results for available ZBTB26 gene related products
- Applied Biological Materials Clones for ZBTB26
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||
| SP2: | - | - | |||||||||||||||
| SP3: | - | - | |||||||||||||||
| SP4: | - |
Expression for ZBTB26 Gene
This gene is overexpressed in Serum (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZBTB26 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ZBTB26 Gene:
ZBTB26SOURCE GeneReport for Unigene cluster for ZBTB26 Gene:
Hs.5638mRNA Expression by UniProt/SwissProt for ZBTB26 Gene:
Q9HCK0-ZBT26_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for ZBTB26 Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for ZBTB26
-
OriGene qPCR primer pairs for ZBTB26
- genomics-online: primer clones - Search results for available ZBTB26 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZBTB26 Gene
Orthologs for ZBTB26 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZBTB26 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ZBTB26 33 |
|
||
| cow (Bos Taurus) |
Mammalia | ZBTB26 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Zbtb26 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Zbtb26 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ZBTB26 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZBTB26 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZBTB26 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | zbtb26 33 |
|
||
| Str.18248 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | si:ch211-236k19.4 33 |
|
||
| ZBTB26 34 |
|
OneToOne |
- Species where no ortholog for ZBTB26 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for ZBTB26 Gene
- ENSEMBL:
- Gene Tree for ZBTB26 (if available)
- TreeFam:
- Gene Tree for ZBTB26 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZBTB26: view image
Paralogs for ZBTB26 Gene
Variants for ZBTB26 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000114377 | -- | 122,920,027(-) | C/A/T | intron_variant | |
| rs1000224103 | -- | 122,922,589(-) | T/C | intron_variant | |
| rs1000362056 | -- | 122,923,512(-) | C/T | intron_variant | |
| rs1000375108 | -- | 122,923,077(-) | G/A/T | intron_variant | |
| rs1000474320 | -- | 122,928,581(-) | A/G | intron_variant |
Residual Variation Intolerance Score:
14.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.32;
26.15% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZBTB26 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZBTB26
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB26 Gene
Disorders for ZBTB26 Gene
Additional Disease Information for ZBTB26
No disorders were found for ZBTB26 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBTB26 Gene
Publications for ZBTB26 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 3 4 58
- Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
- Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X … Vidal M (Cell 2016) 3 58
Products for ZBTB26 Gene
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 48 available ZBTB26 Antibodies ranked by validation data
- Compare Top ZBTB26 Antibodies
- antibodies-online: Search results for available ZBTB26 related products ranked by validation data
- antibodies-online: Search results for 2 available ZBTB26 Proteins ranked by validation data
- Compare Top ZBTB26 Proteins
- Quality Products:
- GeneTex ZBTB26 Antibody for ZBTB26
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- Horizon Cell Lines for ZBTB26
- genomics-online: cdna clones - Search results for available ZBTB26 gene related products
- orf clones - Search results for available ZBTB26 gene related products
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Sources for ZBTB26 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
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- (155) genomics-online
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- (158) Applied Biosystems
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- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt