Aliases for ZADH2 Gene
External Ids for ZADH2 Gene
Previous GeneCards Identifiers for ZADH2 Gene
GeneCards Summary for ZADH2 Gene
ZADH2 (Zinc Binding Alcohol Dehydrogenase Domain Containing 2) is a Protein Coding gene. Diseases associated with ZADH2 include Retinitis Pigmentosa 42 and Vertical Talus, Congenital. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and transferase activity, transferring acyl groups other than amino-acyl groups. An important paralog of this gene is VAT1.
UniProtKB/Swiss-Prot Summary for ZADH2 Gene
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.