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Aliases for YWHAZ Gene

Aliases for YWHAZ Gene

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta 2 3 5
  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Delta Polypeptide 2 3
  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Zeta Polypeptide 2 3
  • 14-3-3 Delta 2 3
  • 14-3-3 Zeta 2 3
  • KCIP-1 3 4
  • Tyrosine 3/Tryptophan 5 -Monooxygenase Activation Protein, Zeta Polypeptide 3
  • 14-3-3 Protein/Cytosolic Phospholipase A2 3
  • Protein Kinase C Inhibitor Protein-1 3
  • Protein Kinase C Inhibitor Protein 1 4
  • Epididymis Secretory Protein Li 93 3
  • Epididymis Secretory Protein Li 3 3
  • Epididymis Luminal Protein 4 3
  • 14-3-3 Protein Zeta/Delta 3
  • Phospholipase A2 3
  • 14-3-3-Zeta 3
  • HEL-S-93 3
  • HEL-S-3 3
  • YWHAD 3
  • HEL4 3

External Ids for YWHAZ Gene

Previous HGNC Symbols for YWHAZ Gene

  • YWHAD

Previous GeneCards Identifiers for YWHAZ Gene

  • GC08M100936
  • GC08M101999
  • GC08M101599
  • GC08M101887
  • GC08M102000
  • GC08M101930
  • GC08M097128

Summaries for YWHAZ Gene

Entrez Gene Summary for YWHAZ Gene

  • This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]

GeneCards Summary for YWHAZ Gene

YWHAZ (Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta) is a Protein Coding gene. Among its related pathways are Gene Expression and Akt Signaling. Gene Ontology (GO) annotations related to this gene include protein kinase binding. An important paralog of this gene is YWHAB.

UniProtKB/Swiss-Prot for YWHAZ Gene

  • Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Tocris Summary for YWHAZ Gene

  • 14.3.3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal transduction, apoptosis and cell cycle regulation. 14.3.3 proteins are phospho-serine/-threonine binding proteins.

Gene Wiki entry for YWHAZ Gene

Additional gene information for YWHAZ Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for YWHAZ Gene

Genomics for YWHAZ Gene

GeneHancer (GH) Regulatory Elements for YWHAZ Gene

Promoters and enhancers for YWHAZ Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J100947 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 697.7 +3.4 3371 7.8 CLOCK ZFP64 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC YWHAZ PABPC1 RNF19A ENSG00000260368 GC08M100949 GC08M100948 GC08P100637
GH08J100955 Enhancer 0.6 ENCODE dbSUPER 650.7 -1.2 -1212 0.2 L3MBTL2 FEZF1 PIR61963 YWHAZ GC08P100637
GH08J100985 Enhancer 1.1 Ensembl ENCODE 46 -32.1 -32053 1.9 HDGF PKNOX1 CLOCK ARNT SIN3A ZNF766 FOS ZNF592 SNIP1 MEF2D YWHAZ RN7SL685P RNF19A PABPC1 GC08M100962 LOC401471 GC08P100637
GH08J100922 Enhancer 0.6 dbSUPER 60.8 +29.1 29128 5.8 SMARCA5 RXRA MAFG EBF1 MEF2B MAFF ZNF316 POLR2A IKZF1 MAFK YWHAZ RN7SL685P ENSG00000260368 GC08M100916 GC08M100934 GC08P100637
GH08J100929 Enhancer 0.7 dbSUPER 46.9 +23.0 23023 5 ZKSCAN1 ZNF121 CTBP1 GATA3 POLR2A ZNF444 IKZF2 SMARCE1 ZNF362 GATAD2B YWHAZ RN7SL685P PABPC1 ENSG00000260368 GC08M100934 GC08M100916 GC08P100637
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around YWHAZ on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the YWHAZ gene promoter:
  • CREB
  • deltaCREB

Genomic Locations for YWHAZ Gene

Genomic Locations for YWHAZ Gene
chr8:100,916,525-100,954,596
(GRCh38/hg38)
Size:
38,072 bases
Orientation:
Minus strand
chr8:101,928,753-101,965,623
(GRCh37/hg19)
Size:
36,871 bases
Orientation:
Minus strand

Genomic View for YWHAZ Gene

Genes around YWHAZ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
YWHAZ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for YWHAZ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for YWHAZ Gene

Proteins for YWHAZ Gene

  • Protein details for YWHAZ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P63104-1433Z_HUMAN
    Recommended name:
    14-3-3 protein zeta/delta
    Protein Accession:
    P63104
    Secondary Accessions:
    • A8K1N0
    • B7Z465
    • P29213
    • P29312
    • Q32P43
    • Q5XJ08
    • Q6GPI2
    • Q6IN74
    • Q6NUR9
    • Q6P3U9
    • Q86V33

    Protein attributes for YWHAZ Gene

    Size:
    245 amino acids
    Molecular mass:
    27745 Da
    Quaternary structure:
    • Interacts with CDK16 and BSPRY (By similarity). Interacts with WEE1 (C-terminal). Interacts with SAMSN1 (By similarity). Interacts with MLF1 (phosphorylated form); the interaction retains it in the cytoplasm (By similarity). Interacts with Thr-phosphorylated ITGB2 (By similarity). Interacts with BCL2L11 (By similarity). Homodimer. Heterodimerizes with YWHAE. Homo- and hetero-dimerization is inhibited by phosphorylation on Ser-58. Interacts with FOXO4, NOXA1, SSH1 and ARHGEF2. Interacts with Pseudomonas aeruginosa exoS (unphosphorylated form). Interacts with BAX; the interaction occurs in the cytoplasm. Under stress conditions, MAPK8-mediated phosphorylation releases BAX to mitochondria. Interacts with phosphorylated RAF1; the interaction is inhibited when YWHAZ is phosphorylated on Thr-232. Interacts with TP53; the interaction enhances p53 transcriptional activity. The Ser-58 phosphorylated form inhibits this interaction and p53 transcriptional activity. Interacts with ABL1 (phosphorylated form); the interaction retains ABL1 in the cytoplasm. Interacts with PKA-phosphorylated AANAT; the interaction modulates AANAT enzymatic activity by increasing affinity for arylalkylamines and acetyl-CoA and protecting the enzyme from dephosphorylation and proteasomal degradation. It may also prevent thiol-dependent inactivation. Interacts with AKT1; the interaction phosphorylates YWHAZ and modulates dimerization. Interacts with GAB2 and TLK2. Interacts with the Thr-369 phosphorylated form of DAPK2 (PubMed:26047703). Interacts with PI4KB, TBC1D22A and TBC1D22B (PubMed:23572552). Interacts with ZFP36L1 (via phosphorylated form); this interaction occurs in a p38 MAPK- and AKT-signaling pathways (By similarity). Interacts with SLITRK1 (PubMed:19640509).
    SequenceCaution:
    • Sequence=AAH51814.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAH73141.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for YWHAZ Gene

    Alternative splice isoforms for YWHAZ Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for YWHAZ Gene

Post-translational modifications for YWHAZ Gene

  • The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Thr-232; inhibits binding of RAF1. Phosphorylated on Ser-58 by PKA and protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53.
  • Ubiquitination at posLast=139139, posLast=4949, posLast=1111, posLast=99, and posLast=33
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Boster Bio Antibodies for YWHAZ
  • Santa Cruz Biotechnology (SCBT) Antibodies for YWHAZ

No data available for DME Specific Peptides for YWHAZ Gene

Domains & Families for YWHAZ Gene

Gene Families for YWHAZ Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for YWHAZ Gene

Graphical View of Domain Structure for InterPro Entry

P63104

UniProtKB/Swiss-Prot:

1433Z_HUMAN :
  • Belongs to the 14-3-3 family.
Family:
  • Belongs to the 14-3-3 family.
genes like me logo Genes that share domains with YWHAZ: view

Function for YWHAZ Gene

Molecular function for YWHAZ Gene

UniProtKB/Swiss-Prot Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
GENATLAS Biochemistry:
tyrosine 3-monooxygenase/trytophan 5 monooxygenase activation protein,14-3-3

Phenotypes From GWAS Catalog for YWHAZ Gene

Gene Ontology (GO) - Molecular Function for YWHAZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding HDA 22658674
GO:0004497 monooxygenase activity IEA --
GO:0005515 protein binding IPI 7935795
GO:0008134 transcription factor binding IPI 16114898
GO:0016301 kinase activity IEA --
genes like me logo Genes that share ontologies with YWHAZ: view
genes like me logo Genes that share phenotypes with YWHAZ: view

Animal Models for YWHAZ Gene

MGI Knock Outs for YWHAZ:
  • Ywhaz Ywhaz<tm1b(EUCOMM)Hmgu>

Animal Model Products

miRNA for YWHAZ Gene

miRTarBase miRNAs that target YWHAZ

Clone Products

  • Addgene plasmids for YWHAZ

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for YWHAZ Gene

Localization for YWHAZ Gene

Subcellular locations from UniProtKB/Swiss-Prot for YWHAZ Gene

Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for YWHAZ gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 5
mitochondrion 3
plasma membrane 2
cytoskeleton 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for YWHAZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 16502470
GO:0005634 nucleus HDA 21630459
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm TAS 16130169
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with YWHAZ: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for YWHAZ Gene

Pathways & Interactions for YWHAZ Gene

genes like me logo Genes that share pathways with YWHAZ: view

Pathways by source for YWHAZ Gene

SIGNOR curated interactions for YWHAZ Gene

Is activated by:
Is inactivated by:
Other effect:

Gene Ontology (GO) - Biological Process for YWHAZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction TAS 16130169
GO:0016310 phosphorylation IEA --
GO:0019221 cytokine-mediated signaling pathway TAS --
GO:0030168 platelet activation TAS --
GO:0043066 negative regulation of apoptotic process TAS 16130169
genes like me logo Genes that share ontologies with YWHAZ: view

Drugs & Compounds for YWHAZ Gene

(3) Drugs for YWHAZ Gene - From: DrugBank, ApexBio, HMDB, and Tocris

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Zolpidem Approved Pharma Full agonist, Allosteric regulator 110
Phenethyl isothiocyanate Investigational Pharma Target 12
R18 Pharma 14.3.3 proteins Antagonist, Inhibitor of 14.3.3 proteins 0

(2) Additional Compounds for YWHAZ Gene - From: HMDB and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Sepiapterin
  • (S)-2-amino-7,8-dihydro-6-(2-Hydroxy-1-oxopropyl)-4(1H)-pteridinone
  • 1-(2-amino-7,8-dihydro-4-Hydroxy-6-pteridinyl)-2-hydroxy-1-propanone
  • 2-amino-6-(S)-Lactoyl-7,8-dihydro-4(3H)-pteridinone
  • 2-amino-7,8-dihydro-6-[(2S)-2-Hydroxy-1-oxopropyl]-4(1H)pteridinone
  • L-Sepiapterin
17094-01-8
Difopein
396834-58-5

(2) Tocris Compounds for YWHAZ Gene

Compound Action Cas Number
Difopein High affinity inhibitor of 14.3.3 proteins; induces apoptosis 396834-58-5
R18 Inhibitor of 14.3.3 proteins 211364-78-2

(1) ApexBio Compounds for YWHAZ Gene

Compound Action Cas Number
R18 14.3.3 proteins Antagonist 211364-78-2
genes like me logo Genes that share compounds with YWHAZ: view

Drug Products

Transcripts for YWHAZ Gene

Unigene Clusters for YWHAZ Gene

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide:
Representative Sequences:

Clone Products

  • Addgene plasmids for YWHAZ

Alternative Splicing Database (ASD) splice patterns (SP) for YWHAZ Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10
SP1: - -
SP2:
SP3: - - - - - - - -
SP4:
SP5:
SP6: -
SP7: -

Relevant External Links for YWHAZ Gene

GeneLoc Exon Structure for
YWHAZ
ECgene alternative splicing isoforms for
YWHAZ

Expression for YWHAZ Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for YWHAZ Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for YWHAZ Gene



Protein tissue co-expression partners for YWHAZ Gene

NURSA nuclear receptor signaling pathways regulating expression of YWHAZ Gene:

YWHAZ

SOURCE GeneReport for Unigene cluster for YWHAZ Gene:

Hs.492407

Evidence on tissue expression from TISSUES for YWHAZ Gene

  • Nervous system(5)
  • Intestine(4.9)
  • Eye(4.8)
  • Skin(4.8)
  • Blood(4.7)
  • Liver(4.6)
  • Bone marrow(4.5)
  • Lung(3.7)
  • Kidney(3)
  • Heart(2.7)
  • Lymph node(2.7)
  • Spleen(2.7)
  • Stomach(2.6)
  • Pancreas(2.5)
  • Muscle(2.4)
  • Gall bladder(2.1)
  • Thyroid gland(2.1)
  • Adrenal gland(2)
genes like me logo Genes that share expression patterns with YWHAZ: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for YWHAZ Gene

Orthologs for YWHAZ Gene

This gene was present in the common ancestor of animals.

Orthologs for YWHAZ Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 100 (a)
OneToMany
-- 34
  • 95 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia YWHAZ 34
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia YWHAZ 33
  • 99.86 (n)
dog
(Canis familiaris)
Mammalia YWHAZ 34 33
  • 97.69 (n)
OneToOne
cow
(Bos Taurus)
Mammalia YWHAZ 34 33
  • 97.69 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Ywhaz 16 34 33
  • 92.93 (n)
rat
(Rattus norvegicus)
Mammalia Ywhaz 33
  • 92.93 (n)
chicken
(Gallus gallus)
Aves YWHAZ 34 33
  • 91.56 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia YWHAZ 34
  • 100 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ywhaz 33
  • 82.45 (n)
MGC75570 33
zebrafish
(Danio rerio)
Actinopterygii ywhaz 34
  • 78 (a)
ManyToMany
ywhabl 33
  • 73.33 (n)
wufb33b01 33
fruit fly
(Drosophila melanogaster)
Insecta 14-3-3&zgr; 35
  • 81 (a)
14-3-3zeta 34 33
  • 70.75 (n)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007643 33
  • 67.62 (n)
worm
(Caenorhabditis elegans)
Secernentea par-5 34
  • 76 (a)
ManyToMany
ftt-2 34 33
  • 70.95 (n)
ManyToMany
Species where no ortholog for YWHAZ was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for YWHAZ Gene

ENSEMBL:
Gene Tree for YWHAZ (if available)
TreeFam:
Gene Tree for YWHAZ (if available)
Aminode:
Evolutionary constrained regions (ECRs) for YWHAZ: view image

Paralogs for YWHAZ Gene

Paralogs for YWHAZ Gene

(9) SIMAP similar genes for YWHAZ Gene using alignment to 11 proteins:

  • 1433Z_HUMAN
  • B0AZS6_HUMAN
  • B7Z2E6_HUMAN
  • D0PNI1_HUMAN
  • E5RGE1_HUMAN
  • E5RIR4_HUMAN
  • E7ESK7_HUMAN
  • E7EVZ2_HUMAN
  • E7EX29_HUMAN
  • E9PD24_HUMAN
  • H0YB80_HUMAN
genes like me logo Genes that share paralogs with YWHAZ: view

Variants for YWHAZ Gene

Sequence variations from dbSNP and Humsavar for YWHAZ Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000115841 -- 100,930,647(-) T/C genic_downstream_transcript_variant, intron_variant
rs1000182180 -- 100,932,034(-) A/G genic_downstream_transcript_variant, intron_variant
rs1000310937 -- 100,946,483(-) G/A genic_downstream_transcript_variant, intron_variant
rs1000317265 -- 100,947,839(-) A/C genic_downstream_transcript_variant, intron_variant
rs1000422586 -- 100,942,862(-) A/G genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for YWHAZ Gene

Variant ID Type Subtype PubMed ID
esv3618198 CNV loss 21293372
esv3891451 CNV gain 25118596
nsv1077061 CNV deletion 25765185
nsv508521 CNV deletion 20534489
nsv831409 CNV loss 17160897
nsv951460 CNV deletion 24416366
nsv971341 CNV duplication 23825009
nsv971342 CNV duplication 23825009

Variation tolerance for YWHAZ Gene

Residual Variation Intolerance Score: 38.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.03; 0.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for YWHAZ Gene

Human Gene Mutation Database (HGMD)
YWHAZ
SNPedia medical, phenotypic, and genealogical associations of SNPs for
YWHAZ

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for YWHAZ Gene

Disorders for YWHAZ Gene

Additional Disease Information for YWHAZ

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for YWHAZ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for YWHAZ Gene

Publications for YWHAZ Gene

  1. ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding. (PMID: 23572552) Greninger AL … DeRisi JL (mBio 2013) 3 4 58
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  3. Examination of association of genes in the serotonin system to autism. (PMID: 19184136) Anderson BM … Haines JL (Neurogenetics 2009) 3 44 58
  4. Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein. (PMID: 19172738) Brummer T … Daly RJ (The EMBO journal 2008) 3 4 58
  5. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PMID: 18951430) Anney RJ … Gill M (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008) 3 44 58

Products for YWHAZ Gene

  • Addgene plasmids for YWHAZ

Sources for YWHAZ Gene