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The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key ... See more...
Aliases for XPO7 Gene
Aliases for XPO7 Gene
External Ids for XPO7 Gene
- HGNC: 14108
- Entrez Gene: 23039
- Ensembl: ENSG00000130227
- OMIM: 606140
- UniProtKB: Q9UIA9
Previous HGNC Symbols for XPO7 Gene
- RANBP16
Previous GeneCards Identifiers for XPO7 Gene
- GC08P022130
- GC08P021597
- GC08P021799
- GC08P021833
- GC08P020319
- GC08P021779
Summaries for XPO7 Gene
-
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
GeneCards Summary for XPO7 Gene
XPO7 (Exportin 7) is a Protein Coding gene. Diseases associated with XPO7 include Hemolytic Anemia and Arts Syndrome. Gene Ontology (GO) annotations related to this gene include binding and nuclear export signal receptor activity. An important paralog of this gene is RANBP17.
UniProtKB/Swiss-Prot Summary for XPO7 Gene
-
Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Additional gene information for XPO7 Gene
- HGNC(14108)
- Entrez Gene(23039)
- Ensembl(ENSG00000130227)
- OMIM(606140)
- UniProtKB(Q9UIA9)
- Open Targets Platform(ENSG00000130227)
- Monarch Initiative
- Search for XPO7 at DataMed
- Search for XPO7 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for XPO7 Gene
Genomics for XPO7 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for XPO7 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around XPO7 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for XPO7
- Top Transcription factor binding sites by QIAGEN in the XPO7 gene promoter:
-
- GATA-2
- Lmo2
- Nkx2-5
- NRSF form 1
- NRSF form 2
- Pax-4a
- POU3F2 (N-Oct-5a)
- POU3F2 (N-Oct-5b)
- RelA
- SRY
Genomic Locations for XPO7 Gene
Genomic Locations for XPO7 Gene
- chr8:21,919,662-22,006,585
- (GRCh38/hg38)
- Size:
- 86,924 bases
- Orientation:
- Plus strand
- chr8:21,777,180-21,864,096
- (GRCh37/hg19)
- Size:
- 86,917 bases
- Orientation:
- Plus strand
Genomic View for XPO7 Gene
Genes around XPO7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p21.3 by HGNC
- 8p21.3 by Entrez Gene
- 8p21.3 by Ensembl
XPO7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for XPO7 Gene
Proteins for XPO7 Gene
-
Protein details for XPO7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UIA9-XPO7_HUMAN
- Recommended name:
- Exportin-7
- Protein Accession:
- Q9UIA9
- O94846
- Q6PJK9
- Q8NEK7
Protein attributes for XPO7 Gene
- Size:
- 1087 amino acids
- Molecular mass:
- 123907 Da
- Quaternary structure:
-
- Binds to nucleoporins. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with ARHGAP1 and SFN. Interacts with Ran and cargo proteins in a GTP-dependent manner.
- SequenceCaution:
-
- Sequence=BAA34465.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for XPO7 Gene
Post-translational modifications for XPO7 Gene
Other Protein References for XPO7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-XPO7 (aa 902-1082) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for XPO7
- Novus Biologicals Antibodies for XPO7
-
Abcam antibodies for XPO7
- Invitrogen Antibodies for XPO7 (AFLGC-Xpo7)
-
Boster Bio Antibodies for XPO7
-
Santa Cruz Biotechnology (SCBT) Antibodies for XPO7
Protein Products
-
OriGene Purified Proteins for XPO7
- Search Origene for MassSpec and Protein Over-expression Lysates for XPO7
- Origene Custom Protein Services for XPO7
- Novus Biologicals proteins for XPO7
- antibodies-online: Search results for available XPO7 related products ranked by validation data
-
Abcam proteins for XPO7
No data available for DME Specific Peptides for XPO7 Gene
Domains & Families for XPO7 Gene
Gene Families for XPO7 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
- Transporters
Protein Domains for XPO7 Gene
- InterPro:
- Blocks:
-
- Importin-beta, N-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for XPO7 Gene
- GenScript: Design optimal peptide antigens:
-
- Exportin 7, isoform CRA_c (D3DSQ7_HUMAN)
- Ran-binding protein 16 (XPO7_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9UIA9- Family:
-
- Belongs to the exportin family.
Function for XPO7 Gene
Molecular function for XPO7 Gene
- UniProtKB/Swiss-Prot Function:
- Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Phenotypes From GWAS Catalog for XPO7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005049 | nuclear export signal receptor activity | IDA | 11024021 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008536 | Ran GTPase binding | IEA | -- |
Phenotypes for XPO7 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for XPO7 - Select products 50% OFF >
- * XPO7 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for XPO7
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for XPO7
-
Santa Cruz Biotechnology (SCBT) CRISPR for XPO7
miRNA for XPO7 Gene
- miRTarBase miRNAs that target XPO7
-
- mmu-miR-24-3p (MIRT013904)
- hsa-miR-103a-3p (MIRT027121)
- hsa-miR-101-3p (MIRT027326)
- hsa-miR-16-5p (MIRT031797)
- hsa-let-7b-5p (MIRT032321)
- hsa-miR-92b-3p (MIRT040588)
- hsa-miR-193b-3p (MIRT041437)
- hsa-miR-484 (MIRT042298)
- hsa-miR-186-5p (MIRT045032)
- hsa-miR-10b-5p (MIRT047422)
- hsa-miR-10a-5p (MIRT047596)
- hsa-miR-30a-5p (MIRT049942)
- hsa-miR-6844 (MIRT447860)
- hsa-miR-8081 (MIRT447861)
- hsa-miR-627-5p (MIRT447862)
- hsa-miR-937-5p (MIRT447863)
- hsa-miR-5702 (MIRT447864)
- mmu-miR-712-5p (MIRT579947)
- mmu-miR-876-5p (MIRT579948)
- mmu-miR-129-5p (MIRT579949)
- mmu-miR-374b-5p (MIRT579950)
- mmu-miR-369-3p (MIRT579951)
- mmu-miR-1896 (MIRT588454)
- mmu-miR-1199-5p (MIRT588455)
- mmu-miR-139-5p (MIRT588456)
- mmu-miR-582-5p (MIRT588457)
- mmu-miR-1194 (MIRT600166)
- mmu-miR-3105-5p (MIRT600167)
- mmu-miR-1929-5p (MIRT600168)
- mmu-miR-382-5p (MIRT600169)
- mmu-miR-511-3p (MIRT602942)
- mmu-miR-762 (MIRT602943)
- mmu-miR-3473b (MIRT602944)
- mmu-miR-1964-5p (MIRT602945)
- mmu-miR-3473a (MIRT602946)
- mmu-miR-185-5p (MIRT602947)
- mmu-miR-882 (MIRT602948)
- mmu-miR-741-3p (MIRT602949)
- mmu-miR-3106-5p (MIRT602950)
- mmu-miR-140-5p (MIRT602951)
- mmu-miR-876-3p (MIRT602952)
- mmu-miR-713 (MIRT602953)
- mmu-miR-1195 (MIRT602954)
- mmu-miR-3089-5p (MIRT602955)
- mmu-miR-743b-5p (MIRT602956)
- mmu-miR-546 (MIRT602957)
- mmu-miR-5114 (MIRT602958)
- mmu-miR-3961 (MIRT602959)
- mmu-miR-122-5p (MIRT602960)
- mmu-miR-5133 (MIRT602961)
- mmu-miR-3475-3p (MIRT602962)
- mmu-miR-1928 (MIRT604543)
- mmu-miR-221-3p (MIRT604544)
- mmu-miR-222-3p (MIRT604545)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for XPO7
- Browse OriGene Inhibitory RNA Products For XPO7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for XPO7
Clone Products
- Applied Biological Materials (abm): Clones for XPO7 - Select products 50% OFF >
- * XPO7 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for XPO7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for XPO7
Cell Line Products
-
Horizon Cell Lines for XPO7
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for XPO7 Gene
Localization for XPO7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for XPO7 Gene
- Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269 PubMed:11024021}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 11071879 |
| GO:0005643 | nuclear pore | IBA,IDA | 11024021 |
| GO:0005737 | cytoplasm | IBA,IDA | 11071879 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for XPO7 Gene
Pathways & Interactions for XPO7 Gene
Interacting Proteins for XPO7 Gene
Selected Interacting proteins:
Q9UIA9-XPO7_HUMAN
ENSP00000252512
for XPO7 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for XPO7
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006611 | protein export from nucleus | IDA | 11024021 |
| GO:0006886 | intracellular protein transport | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
| GO:0051028 | mRNA transport | IEA | -- |
| GO:0051169 | nuclear transport | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for XPO7 Gene
Drugs & Compounds for XPO7 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for XPO7 Gene
mRNA/cDNA for XPO7 Gene
- 4 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000252512 4870 nts (view in UCSC)
- ENST00000433566 4519 nts (view in UCSC)
- ENST00000517551 883 nts (view in UCSC)
- ENST00000518017 939 nts (view in UCSC)
- ENST00000518808 1004 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for XPO7 - Select products 50% OFF >
- * XPO7 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for XPO7
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for XPO7
-
Santa Cruz Biotechnology (SCBT) CRISPR for XPO7
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for XPO7
- Browse OriGene Inhibitory RNA Products For XPO7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for XPO7
Clone Products
- Applied Biological Materials (abm): Clones for XPO7 - Select products 50% OFF >
- * XPO7 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for XPO7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for XPO7
Relevant External Links for XPO7 Gene
- GeneLoc Exon Structure for
- XPO7
Expression for XPO7 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
- Erythroblasts Hematopoietic Bone Marrow
- Umbilical cord blood-derived hematopoietic stem cells
- Umbilical cord blood-derived hematopoietic stem cells (family)
- Umbilical Cord (Extraembryonic Tissues)
- Bone (Muscoskeletal System)
-
Spleen (Hematopoietic System)
-
Testis (Reproductive System)
-
Liver (Hepatobiliary System)
This gene is overexpressed in Bone (44.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for XPO7 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for XPO7
SOURCE GeneReport for Unigene cluster for XPO7 Gene:
Hs.172685mRNA Expression by UniProt/SwissProt for XPO7 Gene:
Q9UIA9-XPO7_HUMAN
Tissue specificity:
Strong expression in testis, thyroid and bone marrow, low expression in lung, liver and small intestine, no expression in thymus, and remaining tissues studied have moderate expression. Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.
Evidence on tissue expression from TISSUES for XPO7 Gene
- Nervous system(4.8)
- Liver(4.5)
- Lung(4.3)
- Heart(2.5)
- Skin(2.5)
- Blood(2.3)
Primer Products
-
OriGene qPCR primer pairs for XPO7
-
OriGene qPCR primer pairs and template standards for XPO7
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for XPO7 Gene
Orthologs for XPO7 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | XPO7 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | XPO7 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | XPO7 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | XPO7 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Xpo7 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Xpo7 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | XPO7 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | XPO7 30 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | xpo7 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.2294 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | xpo7 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004535 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Ranbp16 30 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | C35A5.8 30 31 |
|
OneToMany | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT5G06120 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for XPO7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for XPO7 Gene
- ENSEMBL:
- Gene Tree for XPO7 (if available)
- TreeFam:
- Gene Tree for XPO7 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for XPO7: view image
Paralogs for XPO7 Gene
Variants for XPO7 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for XPO7 Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 691470 | Uncertain Significance: Pyloric stenosis; Esophageal atresia | 21,966,948(+) | T/G | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT | |
| 708348 | Benign: not provided | 21,970,193(+) | C/T | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| rs17856894 | - | p.Glu398Asp | |||
| rs17856895 | - | p.Cys835Tyr |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv7131n100 | CNV | gain | 25217958 |
| dgv7132n100 | CNV | gain | 25217958 |
| dgv7133n100 | CNV | gain | 25217958 |
| dgv7134n100 | CNV | gain | 25217958 |
| dgv7135n100 | CNV | loss | 25217958 |
| esv2736744 | CNV | deletion | 23290073 |
| esv2759604 | CNV | loss | 17122850 |
| esv3383227 | CNV | duplication | 20981092 |
| nsv1019785 | CNV | gain+loss | 25217958 |
| nsv1023009 | CNV | gain | 25217958 |
| nsv1032771 | CNV | loss | 25217958 |
| nsv8319 | CNV | gain | 18304495 |
Residual Variation Intolerance Score:
2.72% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.78;
16.37% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for XPO7 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for XPO7 Gene
Disorders for XPO7 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hemolytic anemia |
|
|
| arts syndrome |
|
|
| anemia, congenital dyserythropoietic, type iv |
|
|
Search XPO7 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for XPO7
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for XPO7 Gene
Publications for XPO7 Gene
- Exportin 7 defines a novel general nuclear export pathway. (PMID: 15282546) Mingot JM … Görlich D (The EMBO journal 2004) 3 4 23
- Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily. (PMID: 11024021) Kutay U … Bischoff FR (The Journal of biological chemistry 2000) 2 3 4
- Identification of a novel putative Ran-binding protein and its close homologue. (PMID: 11071879) Koch P … Janssen JW (Biochemical and biophysical research communications 2000) 3 4 23
- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 9872452) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 2 3 4
- Genome-wide association study of hematological and biochemical traits in a Japanese population. (PMID: 20139978) Kamatani Y … Kamatani N (Nature genetics 2010) 3 41
ExternalLinks
Products for XPO7 Gene
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- Browse OriGene Inhibitory RNA Products For XPO7
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for XPO7 (AFLGC-Xpo7)
- VectorBuilder Custom and pre-made DNA vectors for XPO7 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for XPO7 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for XPO7 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for XPO7 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for XPO7
- antibodies-online: Show 10 available XPO7 Antibodies ranked by validation data
- Compare Top XPO7 Antibodies
- antibodies-online: Search results for available XPO7 related products ranked by validation data
- antibodies-online: Search results for available XPO7 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for XPO7
- Search Santa Cruz Biotechnology (SCBT) for XPO7 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for XPO7
- Horizon Cell Lines for XPO7
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for XPO7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for XPO7
- Search GeneCopoeia for miRNA 3'UTR Target clone products for XPO7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for XPO7
- Boster Bio Antibodies for XPO7
- Browse Boster Bio ELISA Kits
Sources for XPO7 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB