Aliases for XPO6 Gene
External Ids for XPO6 Gene
Previous HGNC Symbols for XPO6 Gene
Previous GeneCards Identifiers for XPO6 Gene
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
GeneCards Summary for XPO6 Gene
XPO6 (Exportin 6) is a Protein Coding gene. Diseases associated with XPO6 include Arts Syndrome and Baraitser-Winter Syndrome. Gene Ontology (GO) annotations related to this gene include binding and Ran GTPase binding.
UniProtKB/Swiss-Prot Summary for XPO6 Gene
Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.