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Aliases for XKRY Gene

Aliases for XKRY Gene

  • XK Related, Y-Linked 2 3 5
  • XK, Kell Blood Group Complex Subunit-Related, Y-Linked 2 3
  • X Kell Blood Group Precursor-Related, Y-Linked 2 3
  • XKRY1 3 4
  • Testis-Specific XK-Related Protein, Y-Linked 2 3
  • X-Linked Kx Blood Group Related, Y-Linked 3
  • Testis-Specific XK-Related Protein On Y 3

External Ids for XKRY Gene

Previous GeneCards Identifiers for XKRY Gene

  • GC0YP019502
  • GC0YM019127
  • GC0YM018826
  • GC0YU900246
  • GC0YM018390
  • GC0YM019880

Summaries for XKRY Gene

Entrez Gene Summary for XKRY Gene

  • This gene is located in the nonrecombining portion of the Y chromosome, and is expressed specifically in testis. It encodes a protein which is similar to XK (X-linked Kell blood group precursor), a putative membrane transport protein. This gene is present as two identical copies within a palindromic region; this record represents the more centromeric copy. [provided by RefSeq, Jul 2008]

GeneCards Summary for XKRY Gene

XKRY (XK Related, Y-Linked) is a Protein Coding gene. Diseases associated with XKRY include Spermatogenic Failure, Y-Linked, 2. An important paralog of this gene is XKRY2.

Additional gene information for XKRY Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for XKRY Gene

Genomics for XKRY Gene

GeneHancer (GH) Regulatory Elements for XKRY Gene

Top Transcription factor binding sites by QIAGEN in the XKRY gene promoter:

Genomic Locations for XKRY Gene

Genomic Locations for XKRY Gene
8,421 bases
Minus strand

Genomic View for XKRY Gene

Genes around XKRY on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
XKRY Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for XKRY Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for XKRY Gene

Proteins for XKRY Gene

  • Protein details for XKRY Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Testis-specific XK-related protein, Y-linked
    Protein Accession:

    Protein attributes for XKRY Gene

    159 amino acids
    Molecular mass:
    18083 Da
    Quaternary structure:
    No Data Available

neXtProt entry for XKRY Gene

Post-translational modifications for XKRY Gene

No Post-translational modifications

Other Protein References for XKRY Gene

REFSEQ proteins:

No data available for DME Specific Peptides for XKRY Gene

Domains & Families for XKRY Gene

Gene Families for XKRY Gene

Protein Domains for XKRY Gene


Suggested Antigen Peptide Sequences for XKRY Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the XK family.
  • Belongs to the XK family.
genes like me logo Genes that share domains with XKRY: view

Function for XKRY Gene

Phenotypes for XKRY Gene

GenomeRNAi human phenotypes for XKRY:
genes like me logo Genes that share phenotypes with XKRY: view

Human Phenotype Ontology for XKRY Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for XKRY Gene

Localization for XKRY Gene

Subcellular locations from UniProtKB/Swiss-Prot for XKRY Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for XKRY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with XKRY: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for XKRY Gene

Pathways & Interactions for XKRY Gene

No Data Available

Interacting Proteins for XKRY Gene

Selected Interacting proteins: O14609-XKRY_HUMAN for XKRY Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for XKRY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007338 single fertilization TAS 9381176
genes like me logo Genes that share ontologies with XKRY: view

No data available for Pathways by source and SIGNOR curated interactions for XKRY Gene

Drugs & Compounds for XKRY Gene

No Compound Related Data Available

Transcripts for XKRY Gene

mRNA/cDNA for XKRY Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for XKRY Gene

No ASD Table

Relevant External Links for XKRY Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for XKRY Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for XKRY Gene

NURSA nuclear receptor signaling pathways regulating expression of XKRY Gene:


SOURCE GeneReport for Unigene cluster for XKRY Gene:


mRNA Expression by UniProt/SwissProt for XKRY Gene:

Tissue specificity: Testis specific.
genes like me logo Genes that share expression patterns with XKRY: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for XKRY Gene

Orthologs for XKRY Gene

Evolution for XKRY Gene

Gene Tree for XKRY (if available)
Gene Tree for XKRY (if available)

No data available for Orthologs for XKRY Gene

Paralogs for XKRY Gene

Paralogs for XKRY Gene

(3) SIMAP similar genes for XKRY Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with XKRY: view

Variants for XKRY Gene

Structural Variations from Database of Genomic Variants (DGV) for XKRY Gene

Variant ID Type Subtype PubMed ID
nsv469717 CNV gain 16826518
esv3575099 CNV loss 25503493
esv1670141 OTHER inversion 17803354

Additional Variant Information for XKRY Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for XKRY Gene

Disorders for XKRY Gene

MalaCards: The human disease database

(1) MalaCards diseases for XKRY Gene - From: GTR

Disorder Aliases PubMed IDs
spermatogenic failure, y-linked, 2
  • spgfy2
- elite association - COSMIC cancer census association via MalaCards
Search XKRY in MalaCards View complete list of genes associated with diseases

Additional Disease Information for XKRY

genes like me logo Genes that share disorders with XKRY: view

No data available for UniProtKB/Swiss-Prot and Genatlas for XKRY Gene

Publications for XKRY Gene

  1. Functional coherence of the human Y chromosome. (PMID: 9381176) Lahn BT … Page DC (Science (New York, N.Y.) 1997) 2 3 4 58
  2. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. (PMID: 12815422) Skaletsky H … Page DC (Nature 2003) 3 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. Kell and Kx, two disulfide-linked proteins of the human erythrocyte membrane are phosphorylated in vivo. (PMID: 9647734) Carbonnet F … Bertrand O (Biochemical and biophysical research communications 1998) 3 58

Products for XKRY Gene

Sources for XKRY Gene

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