Aliases for WSB2 Gene
External Ids for WSB2 Gene
Previous GeneCards Identifiers for WSB2 Gene
This gene encodes a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
GeneCards Summary for WSB2 Gene
WSB2 (WD Repeat And SOCS Box Containing 2) is a Protein Coding gene. An important paralog of this gene is WSB1.
UniProtKB/Swiss-Prot Summary for WSB2 Gene
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.