Aliases for WNT7B Gene
External Ids for WNT7B Gene
Previous GeneCards Identifiers for WNT7B Gene
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]
GeneCards Summary for WNT7B Gene
WNT7B (Wnt Family Member 7B) is a Protein Coding gene. Diseases associated with WNT7B include Microphthalmia, Syndromic 9 and Exudative Vitreoretinopathy 1. Among its related pathways are Signaling by GPCR and Gastric cancer. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and frizzled binding. An important paralog of this gene is WNT7A.
UniProtKB/Swiss-Prot Summary for WNT7B Gene
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:30026314). Required for normal fusion of the chorion and the allantois during placenta development (By similarity). Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (PubMed:30026314).