Aliases for WNT2B Gene
External Ids for WNT2B Gene
Previous HGNC Symbols for WNT2B Gene
Previous GeneCards Identifiers for WNT2B Gene
This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
GeneCards Summary for WNT2B Gene
WNT2B (Wnt Family Member 2B) is a Protein Coding gene. Diseases associated with WNT2B include Diarrhea 9 and Diarrhea. Among its related pathways are Signaling by GPCR and Gastric cancer. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and frizzled binding. An important paralog of this gene is WNT2.
UniProtKB/Swiss-Prot Summary for WNT2B Gene
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.