Aliases for WNT2B Gene
External Ids for WNT2B Gene
Previous HGNC Symbols for WNT2B Gene
Previous GeneCards Identifiers for WNT2B Gene
This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
GeneCards Summary for WNT2B Gene
WNT2B (Wnt Family Member 2B) is a Protein Coding gene. Diseases associated with WNT2B include Gastric Cancer. Among its related pathways are DNA Damage Response (only ATM dependent) and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include receptor binding and frizzled binding. An important paralog of this gene is WNT2.
UniProtKB/Swiss-Prot for WNT2B Gene
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.