Aliases for WNT2 Gene
External Ids for WNT2 Gene
Previous HGNC Symbols for WNT2 Gene
Previous GeneCards Identifiers for WNT2 Gene
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for WNT2 Gene
WNT2 (Wnt Family Member 2) is a Protein Coding gene. Diseases associated with WNT2 include Autism and Colorectal Cancer. Among its related pathways are DNA Damage Response (only ATM dependent) and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include receptor binding and frizzled binding. An important paralog of this gene is WNT2B.
UniProtKB/Swiss-Prot for WNT2 Gene
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.