Aliases for WNT11 Gene
External Ids for WNT11 Gene
Previous GeneCards Identifiers for WNT11 Gene
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]
GeneCards Summary for WNT11 Gene
WNT11 (Wnt Family Member 11) is a Protein Coding gene. Diseases associated with WNT11 include Mass Syndrome. Among its related pathways are DNA Damage Response (only ATM dependent) and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include receptor binding and transcription regulatory region DNA binding. An important paralog of this gene is WNT5B.
UniProtKB/Swiss-Prot for WNT11 Gene
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.