Aliases for WLS Gene
External Ids for WLS Gene
Previous HGNC Symbols for WLS Gene
Previous GeneCards Identifiers for WLS Gene
GeneCards Summary for WLS Gene
WLS (Wnt Ligand Secretion Mediator) is a Protein Coding gene. Diseases associated with WLS include Mental Retardation With Language Impairment And With Or Without Autistic Features and Focal Dermal Hypoplasia. Among its related pathways are Signaling by GPCR and Signaling by Wnt. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and mu-type opioid receptor binding.
UniProtKB/Swiss-Prot Summary for WLS Gene
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).