Aliases for WFDC8 Gene
External Ids for WFDC8 Gene
Previous HGNC Symbols for WFDC8 Gene
Previous GeneCards Identifiers for WFDC8 Gene
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for WFDC8 Gene
WFDC8 (WAP Four-Disulfide Core Domain 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and peptidase inhibitor activity. An important paralog of this gene is EPPIN-WFDC6.