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Aliases for WDR83OS Gene

Aliases for WDR83OS Gene

  • WD Repeat Domain 83 Opposite Strand 2 3 4 5
  • WDR83 Opposite Strand 3 4
  • Protein Asterix 3 4
  • C19orf56 3 4
  • Chromosome 19 Open Reading Frame 56 2
  • UPF0139 Membrane Protein C19orf56 3
  • PTD008 3

External Ids for WDR83OS Gene

Previous HGNC Symbols for WDR83OS Gene

  • C19orf56

Previous GeneCards Identifiers for WDR83OS Gene

  • GC19M012779

Summaries for WDR83OS Gene

GeneCards Summary for WDR83OS Gene

WDR83OS (WD Repeat Domain 83 Opposite Strand) is a Protein Coding gene.

Additional gene information for WDR83OS Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR83OS Gene

Genomics for WDR83OS Gene

GeneHancer (GH) Regulatory Elements for WDR83OS Gene

Promoters and enhancers for WDR83OS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J012664 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 628.9 +2.0 1972 6.6 SP1 ZFX ELF3 MNT SIX5 NKRF POLR2A GTF2F1 CSDE1 ZNF687 WDR83OS ENSG00000269590 GC19M012663 MAN2B1 WDR83 ZNF490 ZNF20 ZNF44 TRMT1 ZNF136
GH19J012781 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 76.4 -119.6 -119647 16 MTA3 ZNF652 SP1 ZFX CC2D1A ELF3 CTCF MNT SIX5 CBFA2T2 IER2 CCDC130 ZNF136 ZNF44 ZNF791 ZNF564 TRMT1 WDR83OS ZNF442 MRI1
GH19J013148 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 62.8 -483.7 -483741 10.8 MTA3 ZNF652 SP1 ZFX CC2D1A ELF3 MNT SIX5 ZNF148 NKRF STX10 ENSG00000267598 IER2 CCDC130 ZNF136 TRMT1 ZNF44 ZNF564 WDR83OS RFX1
GH19J013115 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 47.5 -449.3 -449285 7.7 MTA3 ZFX SP1 CC2D1A ELF3 ZKSCAN8 MNT SIX5 CBFA2T2 ZNF148 TRMT1 NACC1 ZNF791 ZNF136 CCDC130 MRI1 WDR83OS ZNF44 ZNF442 ZNF564
GH19J011923 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 53.8 +744.1 744050 4.4 HDGF ZNF652 ZFX SP1 CTCF ZNF148 NKRF POLR2A ZNF121 CEBPG ZNF700 ENSG00000267179 ZNF627 ZNF136 ZNF44 ZNF763 ZNF20 ZNF564 ZNF442 ZNF791
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around WDR83OS on UCSC Golden Path with GeneCards custom track

Genomic Locations for WDR83OS Gene

Genomic Locations for WDR83OS Gene
chr19:12,668,067-12,669,651
(GRCh38/hg38)
Size:
1,585 bases
Orientation:
Minus strand
chr19:12,778,881-12,782,170
(GRCh37/hg19)
Size:
3,290 bases
Orientation:
Minus strand

Genomic View for WDR83OS Gene

Genes around WDR83OS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR83OS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR83OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR83OS Gene

Proteins for WDR83OS Gene

  • Protein details for WDR83OS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y284-ASTER_HUMAN
    Recommended name:
    Protein Asterix
    Protein Accession:
    Q9Y284
    Secondary Accessions:
    • B2R4T8
    • Q9BVI3

    Protein attributes for WDR83OS Gene

    Size:
    106 amino acids
    Molecular mass:
    12068 Da
    Quaternary structure:
    No Data Available

neXtProt entry for WDR83OS Gene

Post-translational modifications for WDR83OS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR83OS Gene

No data available for DME Specific Peptides for WDR83OS Gene

Domains & Families for WDR83OS Gene

Gene Families for WDR83OS Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for WDR83OS Gene

Blocks:
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for WDR83OS Gene

GenScript: Design optimal peptide antigens:
  • UPF0139 membrane protein C19orf56 (CS056_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9Y284

UniProtKB/Swiss-Prot:

ASTER_HUMAN :
  • Belongs to the Asterix family.
Family:
  • Belongs to the Asterix family.
genes like me logo Genes that share domains with WDR83OS: view

Function for WDR83OS Gene

Phenotypes From GWAS Catalog for WDR83OS Gene

genes like me logo Genes that share phenotypes with WDR83OS: view

Animal Model Products

  • Taconic Biosciences Mouse Models for WDR83OS

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR83OS

Clone Products

  • Applied Biological Materials (abm): Clones for WDR83OS - Now 50% OFF >
  • * WDR83OS as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * WDR83OS tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for WDR83OS Gene

Localization for WDR83OS Gene

Subcellular locations from UniProtKB/Swiss-Prot for WDR83OS Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for WDR83OS gene
Compartment Confidence
extracellular 1
nucleus 1
cytosol 1
plasma membrane 0
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for WDR83OS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with WDR83OS: view

Pathways & Interactions for WDR83OS Gene

PathCards logo

SuperPathways for WDR83OS Gene

No Data Available

Interacting Proteins for WDR83OS Gene

STRING Interaction Network Preview (showing top 2 STRING interactants - click image to see details)
https://version11.string-db.org/api/image/network?species=9606&limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000468969%0d9606.ENSP00000327538%0d9606.ENSP00000327214%0d
Selected Interacting proteins: ENSP00000468969 Q9Y284-ASTER_HUMAN for WDR83OS Gene via STRING IID

Gene Ontology (GO) - Biological Process for WDR83OS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for WDR83OS Gene

Drugs & Compounds for WDR83OS Gene

No Compound Related Data Available

Transcripts for WDR83OS Gene

mRNA/cDNA for WDR83OS Gene

(1) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(935) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for WDR83OS Gene

WD repeat domain 83 opposite strand:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR83OS

Clone Products

  • Applied Biological Materials (abm): Clones for WDR83OS - Now 50% OFF >
  • * WDR83OS as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * WDR83OS tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for WDR83OS Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
SP1:
SP2:

Relevant External Links for WDR83OS Gene

GeneLoc Exon Structure for
WDR83OS
ECgene alternative splicing isoforms for
WDR83OS

Expression for WDR83OS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for WDR83OS Gene

Protein differential expression in normal tissues from HIPED for WDR83OS Gene

This gene is overexpressed in Breast (56.1) and Pancreas (12.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for WDR83OS Gene



Protein tissue co-expression partners for WDR83OS Gene

NURSA nuclear receptor signaling pathways regulating expression of WDR83OS Gene:

WDR83OS

SOURCE GeneReport for Unigene cluster for WDR83OS Gene:

Hs.108969

Evidence on tissue expression from TISSUES for WDR83OS Gene

  • Eye(4.3)
  • Intestine(4.3)
  • Liver(4.3)
  • Nervous system(4.3)
  • Thyroid gland(2)
genes like me logo Genes that share expression patterns with WDR83OS: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for WDR83OS Gene

Orthologs for WDR83OS Gene

This gene was present in the common ancestor of animals.

Orthologs for WDR83OS Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR83OS 35 34
  • 100 (n)
OneToOne
cow
(Bos Taurus)
Mammalia WDR83OS 35 34
  • 93.71 (n)
OneToOne
dog
(Canis familiaris)
Mammalia WDR83OS 35 34
  • 93.08 (n)
OneToOne
mouse
(Mus musculus)
Mammalia BC056474 35 34
  • 91.82 (n)
OneToOne
Wdr83os 17
oppossum
(Monodelphis domestica)
Mammalia WDR83OS 35
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR83OS 35
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves WDR83OS 35
  • 89 (a)
OneToOne
C19ORF56 34
  • 82.84 (n)
lizard
(Anolis carolinensis)
Reptilia WDR83OS 35
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr83os 34
  • 76.1 (n)
zebrafish
(Danio rerio)
Actinopterygii WDR83OS 35
  • 88 (a)
OneToOne
zgc:73111 34
  • 76.1 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10674 35 34
  • 66.33 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007000 34
  • 64.31 (n)
worm
(Caenorhabditis elegans)
Secernentea K10B2.4 35 34
  • 62.33 (n)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4150 35
  • 69 (a)
OneToOne
Species where no ortholog for WDR83OS was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for WDR83OS Gene

ENSEMBL:
Gene Tree for WDR83OS (if available)
TreeFam:
Gene Tree for WDR83OS (if available)
Aminode:
Evolutionary constrained regions (ECRs) for WDR83OS: view image

Paralogs for WDR83OS Gene

No data available for Paralogs for WDR83OS Gene

Variants for WDR83OS Gene

Sequence variations from dbSNP and Humsavar for WDR83OS Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000546631 -- 12,669,427(-) C/G 5_prime_UTR_variant
rs1000730248 -- 12,672,374(-) T/C upstream_transcript_variant
rs1000917887 -- 12,669,249(-) G/A/C intron_variant
rs1002339 -- 12,669,973(-) C/A/T 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant
rs1002678776 -- 12,668,191(-) C/T 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for WDR83OS Gene

Variant ID Type Subtype PubMed ID
dgv138n111 CNV deletion 26073780
nsv1160586 CNV duplication 26073780
nsv953977 CNV deletion 24416366

Variation tolerance for WDR83OS Gene

Residual Variation Intolerance Score: 61.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.02; 0.35% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for WDR83OS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
WDR83OS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR83OS Gene

Disorders for WDR83OS Gene

Additional Disease Information for WDR83OS

No disorders were found for WDR83OS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR83OS Gene

Publications for WDR83OS Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai CH … Lin W (Genome research 2000) 2 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity. (PMID: 22645275) Usenovic M … Krainc D (Human molecular genetics 2012) 3 58
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58

Products for WDR83OS Gene

Sources for WDR83OS Gene

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