Aliases for WDR73 Gene
External Ids for WDR73 Gene
Previous GeneCards Identifiers for WDR73 Gene
The protein encoded by this gene is thought to contain multiple WD40 repeats. WD40 repeats are motifs that contain 40-60 amino acids, and usually end with Trp-Asp (WD). This protein is found in the cytoplasm during interphase, but accumulates at the spindle poles and astral microtubules during mitosis. Reduced expression of this gene results in abnormalities in the size and morphology of the nucleus. Mutations in this gene have been associated with Galloway-Mowat syndrome PMID: 25466283), which is a rare autosomal recessive disorder that affects both the central nervous system and kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
GeneCards Summary for WDR73 Gene
UniProtKB/Swiss-Prot Summary for WDR73 Gene
May play a role in the regulation of microtubule organization and dynamics (PubMed:25466283).