Aliases for WDR7 Gene
External Ids for WDR7 Gene
Previous GeneCards Identifiers for WDR7 Gene
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for WDR7 Gene
WDR7 (WD Repeat Domain 7) is a Protein Coding gene. Diseases associated with WDR7 include Optic Atrophy 3, Autosomal Dominant and Ulcerative Stomatitis. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is MAPKBP1.