Aliases for WDR7 Gene
External Ids for WDR7 Gene
Previous GeneCards Identifiers for WDR7 Gene
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for WDR7 Gene
WDR7 (WD Repeat Domain 7) is a Protein Coding gene. Diseases associated with WDR7 include Retinitis Pigmentosa 4 and Retinitis Pigmentosa. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is WDR72.