Aliases for WDR66 Gene
External Ids for WDR66 Gene
Previous GeneCards Identifiers for WDR66 Gene
This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]
GeneCards Summary for WDR66 Gene
WDR66 (WD Repeat Domain 66) is a Protein Coding gene. Diseases associated with WDR66 include Spermatogenic Failure 33 and Non-Syndromic Male Infertility Due To Sperm Motility Disorder. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is EML5.
UniProtKB/Swiss-Prot Summary for WDR66 Gene
Involved in spermatozoa motility (PubMed:30122540, PubMed:30122541). May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).