External Ids for WDR6 Gene
Previous GeneCards Identifiers for WDR6 Gene
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
GeneCards Summary for WDR6 Gene
WDR6 (WD Repeat Domain 6) is a Protein Coding gene. Diseases associated with WDR6 include Tumoral Calcinosis, Normophosphatemic, Familial and Mitochondrial Complex I Deficiency, Nuclear Type 1. Gene Ontology (GO) annotations related to this gene include insulin receptor substrate binding.
UniProtKB/Swiss-Prot Summary for WDR6 Gene
Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.