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Aliases for WDR11 Gene

Aliases for WDR11 Gene

  • WD Repeat Domain 11 2 3 5
  • Bromodomain And WD Repeat-Containing Protein 2 3 4
  • Sensitization To Ricin Complex Subunit 1 2 3
  • WD Repeat-Containing Protein 11 3 4
  • WD Repeat-Containing Protein 15 3 4
  • BRWD2 3 4
  • WDR15 3 4
  • Bromodomain And WD Repeat Domain Containing 2 2
  • WD Repeat Domain 15 3
  • KIAA1351 4
  • DR11 3
  • HH14 3
  • SRI1 3

External Ids for WDR11 Gene

Previous HGNC Symbols for WDR11 Gene

  • BRWD2

Previous GeneCards Identifiers for WDR11 Gene

  • GC10P121529
  • GC10P121854
  • GC10P122741
  • GC10P122275
  • GC10P122600
  • GC10P116240
  • GC10P122610

Summaries for WDR11 Gene

Entrez Gene Summary for WDR11 Gene

  • This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]

GeneCards Summary for WDR11 Gene

WDR11 (WD Repeat Domain 11) is a Protein Coding gene. Diseases associated with WDR11 include Hypogonadotropic Hypogonadism 14 With Or Without Anosmia and Normosmic Congenital Hypogonadotropic Hypogonadism.

UniProtKB/Swiss-Prot for WDR11 Gene

  • Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (PubMed:29426865).

Gene Wiki entry for WDR11 Gene

Additional gene information for WDR11 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR11 Gene

Genomics for WDR11 Gene

GeneHancer (GH) Regulatory Elements for WDR11 Gene

Promoters and enhancers for WDR11 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J120850 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 693.2 +0.6 626 3.2 SP1 CC2D1A ZFX ELF3 SIX5 NKRF POLR2A MLLT1 ZNF121 CEBPG WDR11 WDR11-AS1 SEC23IP MCMBP ENSG00000271670
GH10J121497 Enhancer 0.8 dbSUPER 78.2 +647.8 647824 3.4 NFIB MZF1 PKNOX1 ZNF544 ZNF300 ZNF776 ZNF501 ZNF561 ZNF37A ZBTB44 WDR11 NSMCE4A ATE1 RN7SKP167 FGFR2
GH10J121307 Enhancer 1.2 Ensembl ENCODE 36.8 +457.8 457830 3.6 ZNF121 ZSCAN21 ZBTB7A YY1 SP7 KLF14 PRDM1 ZNF404 MZF1 ZNF547 WDR11 NSMCE4A LOC105378523 GC10M121233
GH10J119871 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 18.3 -979.1 -979058 4.2 SP1 ZNF652 ZFX ELF3 MNT SIX5 ZNF148 NKRF POLR2A CEBPG MCMBP WDR11 TIAL1 INPP5F SEC23IP ENSG00000282413
GH10J121595 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 10.6 +746.2 746157 4.1 SP1 ELF3 CEBPG ZBTB7A SP7 PRDM1 MZF1 GLIS2 PKNOX1 ZBTB8A FGFR2 WDR11 RN7SKP167
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around WDR11 on UCSC Golden Path with GeneCards custom track

Genomic Locations for WDR11 Gene

Genomic Locations for WDR11 Gene
chr10:120,851,175-120,909,526
(GRCh38/hg38)
Size:
58,352 bases
Orientation:
Plus strand
chr10:122,610,687-122,669,038
(GRCh37/hg19)
Size:
58,352 bases
Orientation:
Plus strand

Genomic View for WDR11 Gene

Genes around WDR11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR11 Gene

Proteins for WDR11 Gene

  • Protein details for WDR11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BZH6-WDR11_HUMAN
    Recommended name:
    WD repeat-containing protein 11
    Protein Accession:
    Q9BZH6
    Secondary Accessions:
    • Q5VWA1
    • Q9P2J6

    Protein attributes for WDR11 Gene

    Size:
    1224 amino acids
    Molecular mass:
    136685 Da
    Quaternary structure:
    • Component of the complex WDR11 composed of C17orf75, FAM91A1 and WDR11; FAM91A1 and WDR11 are required for proper location of the complex (PubMed:29426865). Interacts (via the N-terminal and the central portion of the protein) with EMX1 (PubMed:20887964). Interacts with GLI3; the interaction associateS EMX1 with GLI3 (PubMed:29263200). Interacts with TBC1D23; this interaction may be indirect and recruits TBC1D23 to AP-1-derived vesicles (PubMed:29084197, PubMed:29426865).
    SequenceCaution:
    • Sequence=BAA92589.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for WDR11 Gene

Post-translational modifications for WDR11 Gene

  • Ubiquitination at posLast=608608, isoforms=1, 21193, and isoforms=900
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for WDR11 Gene

Domains & Families for WDR11 Gene

Gene Families for WDR11 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for WDR11 Gene

Suggested Antigen Peptide Sequences for WDR11 Gene

GenScript: Design optimal peptide antigens:
  • WD repeat-containing protein 15 (WDR11_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with WDR11: view

No data available for UniProtKB/Swiss-Prot for WDR11 Gene

Function for WDR11 Gene

Molecular function for WDR11 Gene

UniProtKB/Swiss-Prot Function:
Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (PubMed:29426865).

Phenotypes From GWAS Catalog for WDR11 Gene

Gene Ontology (GO) - Molecular Function for WDR11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20887964
genes like me logo Genes that share ontologies with WDR11: view
genes like me logo Genes that share phenotypes with WDR11: view

Human Phenotype Ontology for WDR11 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR11

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for WDR11 Gene

Localization for WDR11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for WDR11 Gene

Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasmic vesicle. Golgi apparatus, trans-Golgi network. Note=Shuttles from the cilium to the nucleus in response to Hh signaling (PubMed:29263200). Might be shuttling between the nucleus and the cytoplasm (PubMed:20887964). {ECO:0000269 PubMed:20887964, ECO:0000269 PubMed:29263200}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for WDR11 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
golgi apparatus 5
cytosol 4
plasma membrane 1
mitochondrion 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Microtubules (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for WDR11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA,IEA 29263200
GO:0005737 cytoplasm IDA 20887964
GO:0005765 lysosomal membrane HDA 17897319
GO:0005794 Golgi apparatus IEA --
GO:0005802 trans-Golgi network IDA 29426865
genes like me logo Genes that share ontologies with WDR11: view

Pathways & Interactions for WDR11 Gene

PathCards logo

SuperPathways for WDR11 Gene

No Data Available

Gene Ontology (GO) - Biological Process for WDR11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport IDA 29426865
GO:0007507 heart development ISS --
GO:0008589 regulation of smoothened signaling pathway ISS --
GO:0035264 multicellular organism growth ISS --
GO:0060271 cilium assembly ISS --
genes like me logo Genes that share ontologies with WDR11: view

No data available for Pathways by source and SIGNOR curated interactions for WDR11 Gene

Drugs & Compounds for WDR11 Gene

No Compound Related Data Available

Transcripts for WDR11 Gene

mRNA/cDNA for WDR11 Gene

Unigene Clusters for WDR11 Gene

WD repeat domain 11:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR11

Alternative Splicing Database (ASD) splice patterns (SP) for WDR11 Gene

No ASD Table

Relevant External Links for WDR11 Gene

GeneLoc Exon Structure for
WDR11
ECgene alternative splicing isoforms for
WDR11

Expression for WDR11 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for WDR11 Gene

Protein differential expression in normal tissues from HIPED for WDR11 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (13.9) and Testis (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for WDR11 Gene



Protein tissue co-expression partners for WDR11 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of WDR11 Gene:

WDR11

SOURCE GeneReport for Unigene cluster for WDR11 Gene:

Hs.144447

mRNA Expression by UniProt/SwissProt for WDR11 Gene:

Q9BZH6-WDR11_HUMAN
Tissue specificity: Ubiquitous.

Evidence on tissue expression from TISSUES for WDR11 Gene

  • Nervous system(4.8)
  • Liver(4.2)
  • Blood(2.5)

Phenotype-based relationships between genes and organs from Gene ORGANizer for WDR11 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • integumentary
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • eye
  • face
  • head
  • hypothalamus
  • jaw
  • larynx
  • lip
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • olfactory bulb
  • pharynx
  • pituitary gland
  • skull
  • vocal cord
Thorax:
  • breast
  • chest wall
  • clavicle
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • kidney
Pelvis:
  • fallopian tube
  • ovary
  • pelvis
  • penis
  • prostate
  • testicle
  • uterus
  • vagina
  • vas deferens
  • vulva
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • hair
  • peripheral nervous system
  • skin
  • spinal column
  • vertebrae
genes like me logo Genes that share expression patterns with WDR11: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for WDR11 Gene

Orthologs for WDR11 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for WDR11 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR11 35 34
  • 99.78 (n)
OneToOne
cow
(Bos Taurus)
Mammalia BRWD2 35
  • 96 (a)
OneToOne
WDR11 34
  • 91.19 (n)
oppossum
(Monodelphis domestica)
Mammalia WDR11 35
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WDR11 35 34
  • 91.39 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR11 35
  • 90 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wdr11 34
  • 87.63 (n)
mouse
(Mus musculus)
Mammalia Wdr11 17 35 34
  • 87.29 (n)
chicken
(Gallus gallus)
Aves WDR11 35 34
  • 78.75 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia WDR11 35
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr11 34
  • 71.28 (n)
Str.9308 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.2767 34
zebrafish
(Danio rerio)
Actinopterygii wdr11 35 34
  • 70.46 (n)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y110A7A.9 35 34
  • 44.5 (n)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G33530 34
  • 40.61 (n)
rice
(Oryza sativa)
Liliopsida Os02g0137000 34
  • 41.64 (n)
Species where no ortholog for WDR11 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for WDR11 Gene

ENSEMBL:
Gene Tree for WDR11 (if available)
TreeFam:
Gene Tree for WDR11 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for WDR11: view image

Paralogs for WDR11 Gene

(1) SIMAP similar genes for WDR11 Gene using alignment to 4 proteins:

  • WDR11_HUMAN
  • S4R3P9_HUMAN
  • S4R3Z0_HUMAN
  • S4R451_HUMAN
genes like me logo Genes that share paralogs with WDR11: view

No data available for Paralogs for WDR11 Gene

Variants for WDR11 Gene

Sequence variations from dbSNP and Humsavar for WDR11 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs139007744 not-provided, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] 120,906,788(+) T/G coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant
rs144440500 not-provided, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] 120,871,218(+) G/A 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant
rs144531702 not-provided, not provided, - 120,904,047(+) A/C coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant
rs201051480 not-provided, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] 120,866,757(+) C/T 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant
rs318240760 pathogenic, not-provided, Hypogonadotropic hypogonadism 14 with or without anosmia, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] 120,871,178(+) G/A/C 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for WDR11 Gene

Variant ID Type Subtype PubMed ID
esv2759784 CNV loss 17122850
esv3305638 CNV mobile element insertion 20981092
esv3406416 CNV insertion 20981092
esv3579148 CNV loss 25503493
esv3624737 CNV gain 21293372
nsv1043485 CNV loss 25217958
nsv428239 CNV gain+loss 18775914
nsv473863 CNV novel sequence insertion 20440878
nsv525609 CNV loss 19592680
nsv7573 CNV insertion 18451855

Variation tolerance for WDR11 Gene

Residual Variation Intolerance Score: 5.56% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.12; 38.67% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for WDR11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
WDR11
Human Gene Mutation Database (HGMD)
WDR11

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR11 Gene

Disorders for WDR11 Gene

MalaCards: The human disease database

(8) MalaCards diseases for WDR11 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
hypogonadotropic hypogonadism 14 with or without anosmia
  • hh14
normosmic congenital hypogonadotropic hypogonadism
  • isolated congenital gonadotropin deficiency
kallmann syndrome
  • hypogonadotropic hypogonadism and anosmia
hypogonadotropic hypogonadism 7 with or without anosmia
  • hh7
pituitary stalk interruption syndrome
  • ectopic neurohypophysis
- elite association - COSMIC cancer census association via MalaCards
Search WDR11 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

WDR11_HUMAN
  • Note=A chromosomal aberration involving WDR11 is found in a form of glioblastoma. Translocation t(10;19)(q26;q13.3) with ZNF320. {ECO:0000269 PubMed:11536051}.
  • Note=A chromosomal aberration involving WDR11 is found in a form of Kallmann syndrome. Translocation 46,XY,t(10;12)(q26.12;q13.11). {ECO:0000269 PubMed:20887964}.
  • Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858]: A disorder characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. In some cases, it is associated with non-reproductive phenotypes, such as anosmia, cleft palate, and sensorineural hearing loss. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In the presence of anosmia, idiopathic hypogonadotropic hypogonadism is referred to as Kallmann syndrome, whereas in the presence of a normal sense of smell, it has been termed normosmic idiopathic hypogonadotropic hypogonadism (nIHH). {ECO:0000269 PubMed:20887964, ECO:0000269 PubMed:29263200}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for WDR11

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with WDR11: view

No data available for Genatlas for WDR11 Gene

Publications for WDR11 Gene

  1. A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (PMID: 11536051) Chernova OB … Cowell JK (Oncogene 2001) 2 3 4 23 58
  2. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
  3. The WDR11 complex facilitates the tethering of AP-1-derived vesicles. (PMID: 29426865) Navarro Negredo P … Robinson MS (Nature communications 2018) 3 4 58
  4. WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome. (PMID: 29263200) Kim YJ … Kim SH (EMBO reports 2018) 3 4 58
  5. TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at the trans-Golgi. (PMID: 29084197) Shin JJH … Munro S (Nature cell biology 2017) 3 4 58

Products for WDR11 Gene

Sources for WDR11 Gene

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