Aliases for WDR11 Gene
Aliases for WDR11 Gene
External Ids for WDR11 Gene
- HGNC: 13831
- Entrez Gene: 55717
- Ensembl: ENSG00000120008
- OMIM: 606417
- UniProtKB: Q9BZH6
Previous HGNC Symbols for WDR11 Gene
- BRWD2
Previous GeneCards Identifiers for WDR11 Gene
- GC10P121529
- GC10P121854
- GC10P122741
- GC10P122275
- GC10P122600
- GC10P116240
- GC10P122610
Summaries for WDR11 Gene
-
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]
GeneCards Summary for WDR11 Gene
WDR11 (WD Repeat Domain 11) is a Protein Coding gene. Diseases associated with WDR11 include Hypogonadotropic Hypogonadism 14 With Or Without Anosmia and Normosmic Congenital Hypogonadotropic Hypogonadism.
UniProtKB/Swiss-Prot for WDR11 Gene
-
Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (PubMed:29426865).
Additional gene information for WDR11 Gene
- Monarch Initiative
- Search for WDR11 at DataMed
- Search for WDR11 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR11 Gene
Genomics for WDR11 Gene
GeneHancer (GH) Regulatory Elements for WDR11 Gene
Promoters and enhancers for WDR11 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around WDR11 on UCSC Golden Path with GeneCards custom track
Genomic Locations for WDR11 Gene
Genomic Locations for WDR11 Gene
- chr10:120,851,175-120,909,526
- (GRCh38/hg38)
- Size:
- 58,352 bases
- Orientation:
- Plus strand
- chr10:122,610,687-122,669,038
- (GRCh37/hg19)
- Size:
- 58,352 bases
- Orientation:
- Plus strand
Genomic View for WDR11 Gene
Genes around WDR11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q26.12 by HGNC
- 10q26.12 by Entrez Gene
- 10q26.12 by Ensembl
WDR11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for WDR11 Gene
Proteins for WDR11 Gene
-
Protein details for WDR11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BZH6-WDR11_HUMAN
- Recommended name:
- WD repeat-containing protein 11
- Protein Accession:
- Q9BZH6
- Q5VWA1
- Q9P2J6
Protein attributes for WDR11 Gene
- Size:
- 1224 amino acids
- Molecular mass:
- 136685 Da
- Quaternary structure:
-
- Component of the complex WDR11 composed of C17orf75, FAM91A1 and WDR11; FAM91A1 and WDR11 are required for proper location of the complex (PubMed:29426865). Interacts (via the N-terminal and the central portion of the protein) with EMX1 (PubMed:20887964). Interacts with GLI3; the interaction associateS EMX1 with GLI3 (PubMed:29263200). Interacts with TBC1D23; this interaction may be indirect and recruits TBC1D23 to AP-1-derived vesicles (PubMed:29084197, PubMed:29426865).
- SequenceCaution:
-
- Sequence=BAA92589.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for WDR11 Gene
Post-translational modifications for WDR11 Gene
Other Protein References for WDR11 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-WDR11 Antibody
-
Custom Antibody ServicesOriGene Antibodies for WDR11
- Novus Biologicals Antibodies for WDR11
-
Abcam antibodies for WDR11
- Invitrogen Antibodies for WDR11 (AFLGC-WDR11)
Protein Products
- Atlas Antibodies PrEST Antigen WDR11
-
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No data available for DME Specific Peptides for WDR11 Gene
Domains & Families for WDR11 Gene
Gene Families for WDR11 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for WDR11 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for WDR11 Gene
- GenScript: Design optimal peptide antigens:
-
- WD repeat-containing protein 15 (WDR11_HUMAN)
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for WDR11 Gene
Function for WDR11 Gene
Molecular function for WDR11 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (PubMed:29426865).
Phenotypes From GWAS Catalog for WDR11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 20887964 |
Phenotypes for WDR11 Gene
- MGI mutant phenotypes for WDR11:
-
inferred from 2 alleles
- cardiovascular system phenotype
- respiratory system phenotype
- limbs/digits/tail phenotype
- vision/eye phenotype
- digestive/alimentary phenotype
- nervous system phenotype
- taste/olfaction phenotype
- endocrine/exocrine gland phenotype
- mortality/aging
- cellular phenotype
- craniofacial phenotype
- liver/biliary system phenotype
- reproductive system phenotype
- skeleton phenotype
- embryo phenotype
- renal/urinary system phenotype
- adipose tissue phenotype
- hematopoietic system phenotype
- immune system phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for WDR11:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for WDR11
-
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for WDR11 - Now 50% OFF >
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miRNA for WDR11 Gene
- miRTarBase miRNAs that target WDR11
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for WDR11 - Now 50% OFF >
- * WDR11 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * WDR11 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for WDR11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for WDR11
- genomics-online: cdna clones - Search results for available WDR11 gene related products
- orf clones - Search results for available WDR11 gene related products
Cell Line Products
-
Horizon Cell Lines for WDR11
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for WDR11 Gene
Localization for WDR11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for WDR11 Gene
- Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasmic vesicle. Golgi apparatus, trans-Golgi network. Note=Shuttles from the cilium to the nucleus in response to Hh signaling (PubMed:29263200). Might be shuttling between the nucleus and the cytoplasm (PubMed:20887964). {ECO:0000269 PubMed:20887964, ECO:0000269 PubMed:29263200}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| golgi apparatus | 5 |
| cytosol | 4 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| peroxisome | 0 |
- Cytosol (2)
- Microtubules (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,IEA | 29263200 |
| GO:0005737 | cytoplasm | IDA | 20887964 |
| GO:0005765 | lysosomal membrane | HDA | 17897319 |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0005802 | trans-Golgi network | IDA | 29426865 |
Pathways & Interactions for WDR11 Gene
Interacting Proteins for WDR11 Gene
GPS-Prot Interaction Network for WDR11
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006886 | intracellular protein transport | IDA | 29426865 |
| GO:0007507 | heart development | ISS | -- |
| GO:0008589 | regulation of smoothened signaling pathway | ISS | -- |
| GO:0035264 | multicellular organism growth | ISS | -- |
| GO:0060271 | cilium assembly | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for WDR11 Gene
Drugs & Compounds for WDR11 Gene
No Compound Related Data Available
Drug Products
- Atlas Antibodies PrEST Antigen WDR11
Transcripts for WDR11 Gene
mRNA/cDNA for WDR11 Gene
- (1) REFSEQ mRNAs :
- (16) Additional mRNA sequences :
- (251) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000263461 4545 bps (ENST00000263461.10)
- ENST00000605202 651 bps (ENST00000605202.5)
- ENST00000605543 3010 bps (ENST00000605543.5)
- ENST00000605069 558 bps (ENST00000605069.5)
- ENST00000605178 565 bps (ENST00000605178.5)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for WDR11 - Now 50% OFF >
- * WDR11 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * WDR11 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for WDR11
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for WDR11
- genomics-online: gRNA clones - Search results for available WDR11 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for WDR11
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for WDR11
- Browse OriGene Inhibitory RNA Products For WDR11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR11
- genomics-online: shRNA clones - Search results for available WDR11 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for WDR11 - Now 50% OFF >
- * WDR11 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * WDR11 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for WDR11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for WDR11
- genomics-online: cdna clones - Search results for available WDR11 gene related products
- orf clones - Search results for available WDR11 gene related products
Expression for WDR11 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (13.9) and Testis (9.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for WDR11 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of WDR11 Gene:
WDR11SOURCE GeneReport for Unigene cluster for WDR11 Gene:
Hs.144447mRNA Expression by UniProt/SwissProt for WDR11 Gene:
Q9BZH6-WDR11_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for WDR11 Gene
- Nervous system(4.8)
- Liver(4.2)
- Blood(2.5)
Phenotype-based relationships between genes and organs from Gene ORGANizer for WDR11 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- cerebellum
- cranial nerve
- eye
- face
- head
- hypothalamus
- jaw
- larynx
- lip
- mandible
- maxilla
- mouth
- neck
- nose
- olfactory bulb
- pharynx
- pituitary gland
- skull
- vocal cord
Thorax:
- breast
- chest wall
- clavicle
- rib
- rib cage
- scapula
- sternum
Abdomen:
- kidney
Pelvis:
- fallopian tube
- ovary
- pelvis
- penis
- prostate
- testicle
- uterus
- vagina
- vas deferens
- vulva
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- hair
- peripheral nervous system
- skin
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for WDR11
-
OriGene qPCR primer pairs and template standards for WDR11
- genomics-online: primer clones - Search results for available WDR11 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for WDR11 Gene
Orthologs for WDR11 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | WDR11 35 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | BRWD2 35 |
|
OneToOne | |
| WDR11 34 |
|
||||
| oppossum (Monodelphis domestica) |
Mammalia | WDR11 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | WDR11 35 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | WDR11 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Wdr11 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Wdr11 17 35 34 |
|
||
| chicken (Gallus gallus) |
Aves | WDR11 35 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | WDR11 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | wdr11 34 |
|
||
| Str.9308 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.2767 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | wdr11 35 34 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | Y110A7A.9 35 34 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT3G33530 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os02g0137000 34 |
|
- Species where no ortholog for WDR11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for WDR11 Gene
- ENSEMBL:
- Gene Tree for WDR11 (if available)
- TreeFam:
- Gene Tree for WDR11 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for WDR11: view image
Paralogs for WDR11 Gene
(1) SIMAP similar genes for WDR11 Gene using alignment to 4 proteins:
- WDR11_HUMAN
- S4R3P9_HUMAN
- S4R3Z0_HUMAN
- S4R451_HUMAN
No data available for Paralogs for WDR11 Gene
Variants for WDR11 Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs139007744 | not-provided, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] | 120,906,788(+) | T/G | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant | |
| rs144440500 | not-provided, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] | 120,871,218(+) | G/A | 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs144531702 | not-provided, not provided, - | 120,904,047(+) | A/C | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant | |
| rs201051480 | not-provided, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] | 120,866,757(+) | C/T | 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs318240760 | pathogenic, not-provided, Hypogonadotropic hypogonadism 14 with or without anosmia, not provided, Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858] | 120,871,178(+) | G/A/C | 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759784 | CNV | loss | 17122850 |
| esv3305638 | CNV | mobile element insertion | 20981092 |
| esv3406416 | CNV | insertion | 20981092 |
| esv3579148 | CNV | loss | 25503493 |
| esv3624737 | CNV | gain | 21293372 |
| nsv1043485 | CNV | loss | 25217958 |
| nsv428239 | CNV | gain+loss | 18775914 |
| nsv473863 | CNV | novel sequence insertion | 20440878 |
| nsv525609 | CNV | loss | 19592680 |
| nsv7573 | CNV | insertion | 18451855 |
Residual Variation Intolerance Score:
5.56% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.12;
38.67% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for WDR11 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR11 Gene
Disorders for WDR11 Gene
(8) MalaCards diseases for WDR11 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hypogonadotropic hypogonadism 14 with or without anosmia |
|
|
| normosmic congenital hypogonadotropic hypogonadism |
|
|
| kallmann syndrome |
|
|
| hypogonadotropic hypogonadism 7 with or without anosmia |
|
|
| pituitary stalk interruption syndrome |
|
|
Search WDR11 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
WDR11_HUMAN- Note=A chromosomal aberration involving WDR11 is found in a form of glioblastoma. Translocation t(10;19)(q26;q13.3) with ZNF320. {ECO:0000269 PubMed:11536051}.
- Note=A chromosomal aberration involving WDR11 is found in a form of Kallmann syndrome. Translocation 46,XY,t(10;12)(q26.12;q13.11). {ECO:0000269 PubMed:20887964}.
- Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858]: A disorder characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. In some cases, it is associated with non-reproductive phenotypes, such as anosmia, cleft palate, and sensorineural hearing loss. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In the presence of anosmia, idiopathic hypogonadotropic hypogonadism is referred to as Kallmann syndrome, whereas in the presence of a normal sense of smell, it has been termed normosmic idiopathic hypogonadotropic hypogonadism (nIHH). {ECO:0000269 PubMed:20887964, ECO:0000269 PubMed:29263200}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for WDR11
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for WDR11 Gene
Publications for WDR11 Gene
- A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (PMID: 11536051) Chernova OB … Cowell JK (Oncogene 2001) 2 3 4 23 58
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
- The WDR11 complex facilitates the tethering of AP-1-derived vesicles. (PMID: 29426865) Navarro Negredo P … Robinson MS (Nature communications 2018) 3 4 58
- WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome. (PMID: 29263200) Kim YJ … Kim SH (EMBO reports 2018) 3 4 58
- TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at the trans-Golgi. (PMID: 29084197) Shin JJH … Munro S (Nature cell biology 2017) 3 4 58
ExternalLinks
Products for WDR11 Gene
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- Search Knockout (KO) Validated Antibodies
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- Invitrogen Antibodies for WDR11 (AFLGC-WDR11)
- Cyagen custom Knockout/knockin (KOKI) mouse models for WDR11
- antibodies-online: Search results for 24 available WDR11 Antibodies ranked by validation data
- Compare Top WDR11 Antibodies
- antibodies-online: Search results for available WDR11 related products ranked by validation data
- antibodies-online: Search results for available WDR11 related products ranked by validation data
- Horizon Cell Lines for WDR11
- genomics-online: cdna clones - Search results for available WDR11 gene related products
- orf clones - Search results for available WDR11 gene related products
- genomics-online: gRNA clones - Search results for available WDR11 gene related products
- genomics-online: primer clones - Search results for available WDR11 gene related products
- genomics-online: shRNA clones - Search results for available WDR11 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for WDR11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for WDR11
- Search GeneCopoeia for miRNA 3'UTR Target clone products for WDR11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR11
Sources for WDR11 Gene
- (1) GeneCards
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- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
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- (8) Gene Wiki
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- (24) PharmGKB
- (25) DrugBank
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- (27) UniGene
- (28) AceView
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) HGMD
- (45) GAD
- (46) BGMUT
- (47) HuGE
- (48) Atlas
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) OCA
- (69) Proteopedia
- (70) MOPED
- (71) neXtProt
- (72) Reactome
- (73) GeneGo (Thomson Reuters)
- (74) fRNAdb
- (75) DISEASES
- (76) SIMAP
- (77) GenomeRNAi
- (78) LifeMap
- (79) miRTarBase
- (80) MalaCards
- (81) Invitrogen
- (82) BitterDB
- (83) ESI-BIO
- (84) RefSeq
- (85) BioSystems
- (86) MaxQB
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- (88) BioGPS
- (89) Illumina
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- (93) ApexBio
- (94) Addgene
- (95) antibodies-online
- (96) CYP
- (97) NONCODE
- (98) SwitchGear Genomics
- (99) TreeFam
- (100) PathCards
- (101) GeneReviews
- (102) GeneTex
- (103) Taconic Biosciences
- (104) GTEx
- (105) ProteomicsDB
- (106) SCBT
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- (133) Horizon
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- (137) VectorBuilder
- (138) SNPedia
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- (140) St John's Lab
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- (142) ProteoGenix
- (143) dbSUPER
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- (146) abm
- (147) CrownBio
- (148) Human Protein Atlas
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- (150) Monarch Initiative
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- (161) RNACentral
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- (164) miR2Disease
- (165) DiseaseEnhancer
- (166) Boster Bio
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- (168) Biocompare
- (169) Mastermind