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This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms... See more...
Aliases for WDR1 Gene
Aliases for WDR1 Gene
External Ids for WDR1 Gene
- HGNC: 12754
- Entrez Gene: 9948
- Ensembl: ENSG00000071127
- OMIM: 604734
- UniProtKB: O75083
Previous GeneCards Identifiers for WDR1 Gene
- GC04M009744
- GC04M010026
- GC04M009826
- GC04M009752
- GC04M009685
- GC04M009409
Summaries for WDR1 Gene
-
This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for WDR1 Gene
WDR1 (WD Repeat Domain 1) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Hypertrophy Model. Gene Ontology (GO) annotations related to this gene include actin binding.
UniProtKB/Swiss-Prot Summary for WDR1 Gene
-
Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:15629458). Enhances cofilin-mediated actin severing (By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed:25792565).
Additional gene information for WDR1 Gene
- HGNC(12754)
- Entrez Gene(9948)
- Ensembl(ENSG00000071127)
- OMIM(604734)
- UniProtKB(O75083)
- Open Targets Platform(ENSG00000071127)
- Monarch Initiative
- Search for WDR1 at DataMed
- Search for WDR1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for WDR1 Gene
Genomics for WDR1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for WDR1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around WDR1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for WDR1
- Top Transcription factor binding sites by QIAGEN in the WDR1 gene promoter:
-
- Olf-1
- STAT1
- STAT1alpha
- STAT1beta
- STAT2
- STAT3
- STAT4
- STAT5A
- STAT5B
- STAT6
Genomic Locations for WDR1 Gene
Genomic Locations for WDR1 Gene
- chr4:10,074,339-10,116,949
- (GRCh38/hg38)
- Size:
- 42,611 bases
- Orientation:
- Minus strand
- chr4:10,075,963-10,118,573
- (GRCh37/hg19)
- Size:
- 42,611 bases
- Orientation:
- Minus strand
Genomic View for WDR1 Gene
Genes around WDR1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.1 by HGNC
- 4p16.1 by Entrez Gene
- 4p16.1 by Ensembl
WDR1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for WDR1 Gene
Proteins for WDR1 Gene
-
Protein details for WDR1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75083-WDR1_HUMAN
- Recommended name:
- WD repeat-containing protein 1
- Protein Accession:
- O75083
- A8K6E9
- A8MPU4
- O75313
- Q8N6E5
- Q9UG05
- Q9UG78
- Q9UQE0
Protein attributes for WDR1 Gene
- Size:
- 606 amino acids
- Molecular mass:
- 66194 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAD05045.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing.; Evidence={ECO:0000305};
Protein Expression for WDR1 Gene
Post-translational modifications for WDR1 Gene
Other Protein References for WDR1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ WDR1 Antibody
-
Custom Antibody ServicesOriGene Antibodies for WDR1
- Novus Biologicals Antibodies for WDR1
-
Abcam antibodies for WDR1
- Invitrogen Antibodies for WDR1 (AFLGC-WDR1)
-
Boster Bio Antibodies for WDR1
-
Santa Cruz Biotechnology (SCBT) Antibodies for WDR1
- Sino Biological Antibodies for WDR1
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for WDR1
- Origene Custom Protein Services for WDR1
-
Abcam proteins for WDR1
No data available for DME Specific Peptides for WDR1 Gene
Domains & Families for WDR1 Gene
Gene Families for WDR1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for WDR1 Gene
- InterPro:
- Blocks:
-
- G-protein beta WD-40 repeat signature
- ProtoNet:
Suggested Antigen Peptide Sequences for WDR1 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ58303, highly similar to WD repeat protein 1 (B4DY05_HUMAN)
- WD repeat-containing protein 1 isoform 1 variant (Q53GN4_HUMAN)
- NORI-1 (WDR1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O75083- Family:
-
- Belongs to the WD repeat AIP1 family.
Function for WDR1 Gene
Molecular function for WDR1 Gene
- UniProtKB/Swiss-Prot Function:
- Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:15629458). Enhances cofilin-mediated actin severing (By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed:25792565).
- GENATLAS Biochemistry:
- WD repeat domain 1,homolog to a chick gene upregulated in the acoustically chick basilar papilla
Phenotypes From GWAS Catalog for WDR1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | IEA | -- |
| GO:0005515 | protein binding | IEA | -- |
| GO:0051015 | actin filament binding | ISS | -- |
Phenotypes for WDR1 Gene
- MGI mutant phenotypes for WDR1:
-
inferred from 4 alleles
- immune system phenotype
- normal phenotype
- cardiovascular system phenotype
- cellular phenotype
- mortality/aging
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- hearing/vestibular/ear phenotype
- skeleton phenotype
- hematopoietic system phenotype
- integument phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for WDR1:
Animal Models for WDR1 Gene
- MGI Knock Outs for WDR1:
-
- Wdr1 Wdr1<tm1b(EUCOMM)Hmgu>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for WDR1 - Select products 50% OFF >
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-
OriGene CRISPR knockouts for WDR1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for WDR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for WDR1
miRNA for WDR1 Gene
- miRTarBase miRNAs that target WDR1
-
- mmu-miR-149-5p (MIRT014587)
- hsa-miR-375 (MIRT019985)
- hsa-miR-93-5p (MIRT028095)
- hsa-miR-1226-3p (MIRT036411)
- hsa-miR-877-3p (MIRT036948)
- hsa-miR-615-3p (MIRT039865)
- hsa-miR-92a-3p (MIRT049572)
- hsa-miR-539-5p (MIRT163869)
- hsa-miR-5680 (MIRT163905)
- hsa-miR-218-5p (MIRT439290)
- hsa-miR-20a-5p (MIRT439291)
- hsa-miR-106b-5p (MIRT439293)
- hsa-miR-3178 (MIRT452506)
- hsa-miR-3123 (MIRT452507)
- hsa-miR-3976 (MIRT452508)
- hsa-miR-3925-5p (MIRT452509)
- hsa-miR-3121-3p (MIRT452510)
- hsa-miR-19b-3p (MIRT726105)
- hsa-miR-519d-3p (MIRT726106)
- hsa-miR-19a-3p (MIRT726107)
- hsa-miR-20b-5p (MIRT726108)
- hsa-miR-17-5p (MIRT726109)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for WDR1
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Clone Products
- Applied Biological Materials (abm): Clones for WDR1 - Select products 50% OFF >
- * WDR1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for WDR1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for WDR1
Cell Line Products
-
Horizon Cell Lines for WDR1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for WDR1 Gene
Localization for WDR1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for WDR1 Gene
- Cytoplasm, cytoskeleton. Cell projection, podosome. Cell junction.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| plasma membrane | 4 |
| extracellular | 4 |
| cytoskeleton | 4 |
| nucleus | 3 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cell Junctions (3)
- Plasma membrane (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002102 | podosome | IEA | -- |
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
Pathways & Interactions for WDR1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
| 2 | Hypertrophy Model | ||
Pathways by source for WDR1 Gene
1 BioSystems pathway for WDR1 Gene
4 Reactome pathways for WDR1 Gene
Interacting Proteins for WDR1 Gene
GPS-Prot Interaction Network for WDR1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002446 | neutrophil mediated immunity | IEA | -- |
| GO:0002576 | platelet degranulation | TAS | -- |
| GO:0007605 | sensory perception of sound | TAS | 10036186 |
| GO:0008360 | regulation of cell shape | IEA | -- |
| GO:0030036 | actin cytoskeleton organization | IEA | -- |
No data available for SIGNOR curated interactions for WDR1 Gene
Transcripts for WDR1 Gene
mRNA/cDNA for WDR1 Gene
- 2 REFSEQ mRNAs :
- 23 NCBI additional mRNA sequence :
- 18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000264785 549 nts (view in UCSC)
- ENST00000382451 2722 nts (view in UCSC)
- ENST00000382452 3142 nts (view in UCSC)
- ENST00000499869 2993 nts (view in UCSC)
- ENST00000502702 1691 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for WDR1 - Select products 50% OFF >
- * WDR1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for WDR1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for WDR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for WDR1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for WDR1
- Browse OriGene Inhibitory RNA Products For WDR1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR1
Clone Products
- Applied Biological Materials (abm): Clones for WDR1 - Select products 50% OFF >
- * WDR1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for WDR1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for WDR1
Relevant External Links for WDR1 Gene
- GeneLoc Exon Structure for
- WDR1
Expression for WDR1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for WDR1 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for WDR1
SOURCE GeneReport for Unigene cluster for WDR1 Gene:
Hs.128548Evidence on tissue expression from TISSUES for WDR1 Gene
- Nervous system(5)
- Intestine(4.9)
- Blood(4.7)
- Eye(4.6)
- Skin(4.6)
- Kidney(4.6)
- Liver(4.5)
- Lung(4.1)
- Heart(3.1)
- Pancreas(2.8)
- Muscle(2.8)
- Lymph node(2.6)
- Spleen(2.5)
- Stomach(2.4)
- Thyroid gland(2.4)
- Bone marrow(2.4)
Primer Products
-
OriGene qPCR primer pairs for WDR1
-
OriGene qPCR primer pairs and template standards for WDR1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for WDR1 Gene
Orthologs for WDR1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | WDR1 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | WDR1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | WDR1 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | WDR1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | WDR1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Wdr1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Wdr1 30 17 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | WDR1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | WDR1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | wdr1 30 |
|
||
| Str.11460 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | wdr1 30 |
|
||
| WDR1 31 |
|
OneToOne | |||
| -- 30 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002509 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | flr 30 31 |
|
OneToOne | |
| CG10724 32 |
|
|
|||
| Worm (Caenorhabditis elegans) |
Secernentea | aipl-1 30 31 |
|
OneToMany | |
| K08F9.2 32 |
|
|
|||
| unc-78 31 32 |
|
OneToMany | |||
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_ABL043W 30 |
|
||
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F13750g 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | AIP1 30 31 33 |
|
OneToOne | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT3G18060 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os01g0125800 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU03944 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPAC9G1.05 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.9254 31 |
|
OneToOne |
- Species where no ortholog for WDR1 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for WDR1 Gene
- ENSEMBL:
- Gene Tree for WDR1 (if available)
- TreeFam:
- Gene Tree for WDR1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for WDR1: view image
Paralogs for WDR1 Gene
No data available for Paralogs for WDR1 Gene
Variants for WDR1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for WDR1 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 711389 | Benign: not provided | 10,116,242(-) | G/C | INTRON_VARIANT | |
| 721980 | Likely Benign: not provided | 10,081,348(-) | G/A | INTRON_VARIANT | |
| 722768 | Likely Benign: not provided | 10,097,855(-) | A/T | SYNONYMOUS_VARIANT,INTRON_VARIANT | |
| 737152 | Likely Benign: not provided | 10,097,759(-) | G/A | SYNONYMOUS_VARIANT,INTRON_VARIANT | |
| 738527 | Likely Benign: not provided | 10,083,054(-) | C/T | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5117n100 | CNV | gain | 25217958 |
| esv24360 | CNV | gain+loss | 19812545 |
| esv2752052 | CNV | gain | 17911159 |
| esv2759222 | CNV | gain+loss | 17122850 |
| esv3575678 | CNV | gain | 25503493 |
| esv3599589 | CNV | gain | 21293372 |
| esv3599598 | CNV | gain | 21293372 |
| esv989430 | CNV | deletion | 20482838 |
| nsv1003286 | CNV | gain | 25217958 |
| nsv1005698 | CNV | gain | 25217958 |
| nsv1013487 | CNV | gain | 25217958 |
| nsv1014335 | CNV | gain | 25217958 |
| nsv1074689 | CNV | deletion | 25765185 |
| nsv428438 | CNV | gain | 18775914 |
| nsv469621 | CNV | loss | 16826518 |
| nsv524687 | CNV | gain | 19592680 |
| nsv525589 | CNV | loss | 19592680 |
| nsv829857 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
7.87% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.83;
34.32% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for WDR1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR1 Gene
Disorders for WDR1 Gene
Additional Disease Information for WDR1
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for WDR1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR1 Gene
Publications for WDR1 Gene
- Critical roles of actin-interacting protein 1 in cytokinesis and chemotactic migration of mammalian cells. (PMID: 18494608) Kato A … Mizuno K (The Biochemical journal 2008) 3 4 23
- AIP1/WDR1 supports mitotic cell rounding. (PMID: 15629458) Fujibuchi T … Kito K (Biochemical and biophysical research communications 2005) 3 4 23
- A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein. (PMID: 10036186) Adler HJ … Lomax MI (Genomics 1999) 2 3 4
- Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions. (PMID: 25792565) Lechuga S … Ivanov AI (American journal of physiology. Gastrointestinal and liver physiology 2015) 3 4
- Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. (PMID: 18179892) Wallace C … Munroe PB (American journal of human genetics 2008) 3 41
ExternalLinks
Products for WDR1 Gene
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- OriGene qPCR primer pairs for WDR1
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- VectorBuilder Stable cell line generation for WDR1
- antibodies-online: Show 14 available WDR1 Antibodies ranked by validation data
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- antibodies-online: Search results for available WDR1 related products ranked by validation data
- antibodies-online: Show 5 available WDR1 Proteins ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for WDR1
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- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for WDR1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for WDR1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for WDR1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WDR1
- Boster Bio Antibodies for WDR1
- Browse Boster Bio ELISA Kits
Sources for WDR1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
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- (13) UniProtKB/TrEMBL
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- (24) PharmGKB
- (25) DrugBank
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- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
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- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
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- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB