Aliases for WDFY4 Gene
External Ids for WDFY4 Gene
Previous HGNC Symbols for WDFY4 Gene
Previous GeneCards Identifiers for WDFY4 Gene
GeneCards Summary for WDFY4 Gene
WDFY4 (WDFY Family Member 4) is a Protein Coding gene. Diseases associated with WDFY4 include Systemic Lupus Erythematosus. Gene Ontology (GO) annotations related to this gene include binding and phospholipid binding. An important paralog of this gene is WDFY3.
UniProtKB/Swiss-Prot Summary for WDFY4 Gene
Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.