Aliases for WBP4 Gene
External Ids for WBP4 Gene
Previous GeneCards Identifiers for WBP4 Gene
This gene encodes WW domain-containing binding protein 4. The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. This encoded protein is a general spliceosomal protein that may play a role in cross-intron bridging of U1 and U2 snRNPs in the spliceosomal complex A. [provided by RefSeq, Jul 2008]
GeneCards Summary for WBP4 Gene
WBP4 (WW Domain Binding Protein 4) is a Protein Coding gene. Diseases associated with WBP4 include Cerebral Amyloid Angiopathy, Itm2b-Related, 2. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and proline-rich region binding.
UniProtKB/Swiss-Prot Summary for WBP4 Gene
Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:9724750, PubMed:19592703, PubMed:28781166). May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex (PubMed:9724750).