Aliases for WBP11 Gene
External Ids for WBP11 Gene
Previous GeneCards Identifiers for WBP11 Gene
This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008]
GeneCards Summary for WBP11 Gene
WBP11 (WW Domain Binding Protein 11) is a Protein Coding gene. Diseases associated with WBP11 include Renpenning Syndrome 1. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include WW domain binding.
UniProtKB/Swiss-Prot Summary for WBP11 Gene
Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.