This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell... See more...

Aliases for WASL Gene

Aliases for WASL Gene

  • WASP Like Actin Nucleation Promoting Factor 2 3 5
  • N-WASP 2 3 4
  • Neural Wiskott-Aldrich Syndrome Protein 3 4
  • Wiskott-Aldrich Syndrome Like 2 3
  • NWASP 2 3
  • WASPB 2 3
  • Wiskott-Aldrich Syndrome-Like 2
  • WASL 5

External Ids for WASL Gene

Previous GeneCards Identifiers for WASL Gene

  • GC07M121799
  • GC07M122862
  • GC07M122876
  • GC07M122915
  • GC07M123109
  • GC07M123321
  • GC07M117685

Summaries for WASL Gene

Entrez Gene Summary for WASL Gene

  • This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]

GeneCards Summary for WASL Gene

WASL (WASP Like Actin Nucleation Promoting Factor) is a Protein Coding gene. Diseases associated with WASL include Wiskott-Aldrich Syndrome and Buruli Ulcer. Among its related pathways are Adherens junction and Cell junction organization. Gene Ontology (GO) annotations related to this gene include actin binding and GTPase regulator activity. An important paralog of this gene is WAS.

UniProtKB/Swiss-Prot Summary for WASL Gene

  • Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex (PubMed:9422512, PubMed:16767080, PubMed:19366662, PubMed:19487689, PubMed:22847007, PubMed:22921828). Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization (PubMed:9422512, PubMed:19366662, PubMed:19487689, PubMed:22847007, PubMed:22921828). Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia (PubMed:9422512). In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization (PubMed:16767080). Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression (By similarity). Plays a role in dendrite spine morphogenesis (By similarity). Decreasing levels of DNMBP (using antisense RNA) alters apical junction morphology in cultured enterocytes, junctions curve instead of being nearly linear (PubMed:19767742).

Tocris Summary for WASL Gene

  • Actin is a ubiquitous globular protein that is one of the most highly-conserved proteins known. It is found in two main states: G-actin is the globular monomeric form, whereas F-actin forms helical polymers. Both G- and F-actin are intrinsically flexible structures.

Gene Wiki entry for WASL Gene

No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for WASL Gene

Genomics for WASL Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for WASL Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J123745 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 262.7 +0.2 178 7.2 BCLAF1 SP1 ZNF207 NCOR1 IKZF1 MYC ZNF600 SIX5 JUND ZNF592 WASL 5EW4_A-045 piR-40063-002 WASL-DT HYAL4 LMOD2
GH07J123725 Enhancer 1.1 Ensembl ENCODE 23.2 +23.3 23259 6.3 NCOR1 IKZF1 ZNF600 ZNF592 CEBPA ZIC2 CEBPB FEZF1 ZNF148 IRF2 WASL WASL-DT RNU6-11P HYAL4 IQUB 5EW4_A-045 LMOD2
GH07J123711 Enhancer 0.9 Ensembl ENCODE 22.4 +36.8 36802 3.6 NCOR1 IKZF1 ZNF592 REST NBN PRDM6 ATF1 HLTF STAT5A SMARCA4 WASL RNU6-11P WASL-DT 5EW4_A-045 LMOD2
GH07J123719 Enhancer 0.9 Ensembl ENCODE 22.9 +28.9 28902 3.8 ZNF592 FEZF1 MNT TAL1 ZNF316 NFE2 PRDM6 SMARCA4 MAX RAD51 WASL-DT WASL RNU6-11P 5EW4_A-045 LMOD2
GH07J123714 Enhancer 0.7 Ensembl 22.5 +33.7 33702 2.2 NBN FOSL2 PRDM6 HLTF EHMT2 PKNOX1 HDAC2 JUND TEAD4 MEIS2 WASL RNU6-11P HYAL4 WASL-DT 5EW4_A-045 LMOD2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around WASL on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for WASL

Top Transcription factor binding sites by QIAGEN in the WASL gene promoter:
  • AML1a
  • AP-4
  • C/EBPalpha
  • Elk-1
  • GATA-1
  • Nkx3-1
  • Nkx3-1 v1
  • PPAR-gamma1
  • PPAR-gamma2
  • RORalpha1

Genomic Locations for WASL Gene

Latest Assembly
chr7:123,681,943-123,749,003
(GRCh38/hg38)
Size:
67,061 bases
Orientation:
Minus strand

Previous Assembly
chr7:123,321,997-123,389,057
(GRCh37/hg19 by Entrez Gene)
Size:
67,061 bases
Orientation:
Minus strand

chr7:123,321,989-123,389,121
(GRCh37/hg19 by Ensembl)
Size:
67,133 bases
Orientation:
Minus strand

Genomic View for WASL Gene

Genes around WASL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WASL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WASL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WASL Gene

Proteins for WASL Gene

  • Protein details for WASL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O00401-WASL_HUMAN
    Recommended name:
    Neural Wiskott-Aldrich syndrome protein
    Protein Accession:
    O00401
    Secondary Accessions:
    • A1JUI9
    • Q7Z746

    Protein attributes for WASL Gene

    Size:
    505 amino acids
    Molecular mass:
    54827 Da
    Quaternary structure:
    • Binds actin and the Arp2/3 complex (PubMed:22847007). Interacts with CDC42 (PubMed:9422512). Interacts with FCHSD1 (By similarity). Interacts with FCHSD2 (PubMed:29887380). Binds to SH3 domains of GRB2. Interacts with the C-terminal SH3 domain of DNMBP (PubMed:19767742, PubMed:24332715, PubMed:17015620). Interacts with SNX9 (By similarity). Interacts with the WW domains of PRPF40A/FBP11 (By similarity). Interacts with PTK2/FAK1 (By similarity). Interacts with PACSIN1, PACSIN2 and PACSIN3 (By similarity). Interacts with NOSTRIN (PubMed:16234328). Binds to TNK2 (PubMed:16257963). Interacts with SNX33 (PubMed:19487689). Interacts with NONO (via second RRM domain); the interaction is direct (PubMed:16767080). Component of a multiprotein complex with NONO and SFPQ; associates with the complex via direct interaction with NONO (PubMed:16767080).
    • (Microbial infection) Interacts with E.coli effector protein EspF(U) (PubMed:19366662, PubMed:22921828). Identified in a complex containing at least WASL, BAIAP2L1 and E.coli EspF(U) (PubMed:22921828).
    • (Microbial infection) Interacts with Shigella flexneri protein IcsA (PubMed:9582270, PubMed:10491394). The interaction with IcsA enhances the affinity of WASL for Arp2/3, thus assembling a tight complex which has maximal activity in actin assembly (PubMed:9582270, PubMed:10491394).

    Three dimensional structures from OCA and Proteopedia for WASL Gene

neXtProt entry for WASL Gene

Post-translational modifications for WASL Gene

  • Phosphorylation at Ser-242, Tyr-256, Ser-484 and Ser-485 enhances actin polymerization activity.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WASL Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for WASL Gene

Domains & Families for WASL Gene

Gene Families for WASL Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for WASL Gene

Suggested Antigen Peptide Sequences for WASL Gene

GenScript: Design optimal peptide antigens:
  • WASL protein (A1JUI9_HUMAN)
  • Wiskott-Aldrich syndrome-like (A4D0Y1_HUMAN)
  • Neural Wiskott-Aldrich syndrome protein (WASL_HUMAN)
genes like me logo Genes that share domains with WASL: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for WASL Gene

Function for WASL Gene

Molecular function for WASL Gene

UniProtKB/Swiss-Prot Function:
Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex (PubMed:9422512, PubMed:16767080, PubMed:19366662, PubMed:19487689, PubMed:22847007, PubMed:22921828). Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization (PubMed:9422512, PubMed:19366662, PubMed:19487689, PubMed:22847007, PubMed:22921828). Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia (PubMed:9422512). In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization (PubMed:16767080). Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression (By similarity). Plays a role in dendrite spine morphogenesis (By similarity). Decreasing levels of DNMBP (using antisense RNA) alters apical junction morphology in cultured enterocytes, junctions curve instead of being nearly linear (PubMed:19767742).
GENATLAS Biochemistry:
Wiskott-Aldrich syndrome protein-like,64kDa,neural,concentrated at the nerve terminal region,inducing long actin microspikes when coexpressed with active CDC42

Phenotypes From GWAS Catalog for WASL Gene

Gene Ontology (GO) - Molecular Function for WASL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003779 actin binding IEA --
GO:0005515 protein binding IPI 11231575
GO:0030695 GTPase regulator activity TAS 9422512
genes like me logo Genes that share ontologies with WASL: view
genes like me logo Genes that share phenotypes with WASL: view

miRNA for WASL Gene

miRTarBase miRNAs that target WASL

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WASL

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for WASL Gene

Localization for WASL Gene

Subcellular locations from UniProtKB/Swiss-Prot for WASL Gene

Cytoplasm, cytoskeleton. Nucleus. Cytoplasm. Note=Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated (By similarity). Exported from the nucleus by an nuclear export signal (NES)-dependent mechanism to the cytoplasm (By similarity). {ECO:0000250 UniProtKB:Q91YD9}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for WASL gene
Compartment Confidence
plasma membrane 5
cytoskeleton 5
nucleus 5
cytosol 5
extracellular 4
mitochondrion 2
endoplasmic reticulum 2
endosome 2
lysosome 2
golgi apparatus 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoli (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for WASL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 16767080
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol TAS --
GO:0005856 cytoskeleton IEA --
GO:0005884 actin filament IBA 21873635
genes like me logo Genes that share ontologies with WASL: view

Pathways & Interactions for WASL Gene

genes like me logo Genes that share pathways with WASL: view

Pathways by source for WASL Gene

7 GeneGo (Thomson Reuters) pathways for WASL Gene
  • Cell adhesion Integrin-mediated cell adhesion and migration
  • Cell adhesion_Cadherin-mediated cell adhesion
  • Cytoskeleton remodeling CDC42 in cellular processes
  • Cytoskeleton remodeling Fibronectin-binding integrins in cell motility
  • Cytoskeleton remodeling Reverse signaling by ephrin B
9 Qiagen pathways for WASL Gene
  • Actin Nucleation by ARP-WASP Complex
  • Actin-Based Motility by Rho Family GTPases
  • CDC42 Pathway
  • Epithelial Adherens Junctions
  • Guidance Cues and Growth Cone Motility
1 Cell Signaling Technology pathway for WASL Gene

SIGNOR curated interactions for WASL Gene

Is activated by:
Is inactivated by:
Other effect:

Gene Ontology (GO) - Biological Process for WASL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006900 vesicle budding from membrane ISS --
GO:0007015 actin filament organization IEA --
GO:0007049 cell cycle IEA --
GO:0008154 actin polymerization or depolymerization TAS 9422512
GO:0009617 response to bacterium IEA --
genes like me logo Genes that share ontologies with WASL: view

Drugs & Compounds for WASL Gene

(7) Drugs for WASL Gene - From: ApexBio, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Latrunculin A Experimental Pharma Inhibitor of actin assembly and polymerization 0
187-1, N-WASP inhibitor Pharma N-WASP inhibitor; inhibits actin assembly 0
Wiskostatin Pharma N-WASP inhibitor; inhibits Arp2/3 activation 0
CK 666 Pharma Arp2/3 inhibitor; inhibits actin polymerization 0
CK 869 Pharma Arp2/3 inhibitor; inhibits actin polymerization 0

(8) Additional Compounds for WASL Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs

(5) Tocris Compounds for WASL Gene

Compound Action Cas Number
187-1, N-WASP inhibitor N-WASP inhibitor; inhibits actin assembly 380488-27-7
CK 666 Arp2/3 inhibitor; inhibits actin polymerization 442633-00-3
CK 869 Arp2/3 inhibitor; inhibits actin polymerization 388592-44-7
Latrunculin A Inhibitor of actin assembly and polymerization 76343-93-6
Wiskostatin N-WASP inhibitor; inhibits Arp2/3 activation 253449-04-6

(1) ApexBio Compounds for WASL Gene

Compound Action Cas Number
187-1, N-WASP inhibitor 380488-27-7
genes like me logo Genes that share compounds with WASL: view

Drug products for research

Transcripts for WASL Gene

mRNA/cDNA for WASL Gene

1 REFSEQ mRNAs :
12 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for WASL

Alternative Splicing Database (ASD) splice patterns (SP) for WASL Gene

No ASD Table

Relevant External Links for WASL Gene

GeneLoc Exon Structure for
WASL

Expression for WASL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for WASL Gene

Protein differential expression in normal tissues from HIPED for WASL Gene

This gene is overexpressed in Frontal cortex (10.4), Uterus (7.9), and Testis (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for WASL Gene



Protein tissue co-expression partners for WASL Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for WASL

SOURCE GeneReport for Unigene cluster for WASL Gene:

Hs.143728

Evidence on tissue expression from TISSUES for WASL Gene

  • Nervous system(5)
  • Skin(3.6)
  • Kidney(3.3)
  • Muscle(2.8)
  • Heart(2.7)
  • Intestine(2.5)
  • Spleen(2.5)
  • Liver(2.5)
  • Lung(2.3)
  • Blood(2.3)
  • Adrenal gland(2.3)
  • Stomach(2.1)
genes like me logo Genes that share expression patterns with WASL: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for WASL Gene

Orthologs for WASL Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for WASL Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia WASL 29 30
  • 99.67 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia WASL 30
  • 97 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Wasl 30
  • 96 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia WASL 30
  • 96 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia WASL 30
  • 92 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia -- 30
  • 89 (a)
OneToMany
-- 30
  • 81 (a)
OneToMany
Chicken
(Gallus gallus)
Aves WASL 30
  • 91 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia WASL 30
  • 88 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia Str.2306 29
Zebrafish
(Danio rerio)
Actinopterygii wasla 30
  • 75 (a)
OneToMany
waslb 30
  • 66 (a)
OneToMany
zgc55478 29
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4194 29
Fruit Fly
(Drosophila melanogaster)
Insecta WASp 30
  • 36 (a)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes LAS17 30
  • 21 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.5291 30
  • 45 (a)
OneToMany
Species where no ortholog for WASL was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for WASL Gene

ENSEMBL:
Gene Tree for WASL (if available)
TreeFam:
Gene Tree for WASL (if available)
Aminode:
Evolutionary constrained regions (ECRs) for WASL: view image
Alliance of Genome Resources:
Additional Orthologs for WASL

Paralogs for WASL Gene

Paralogs for WASL Gene

(3) SIMAP similar genes for WASL Gene using alignment to 2 proteins:

  • WASL_HUMAN
  • A4D0Y1_HUMAN
genes like me logo Genes that share paralogs with WASL: view

Variants for WASL Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for WASL Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for WASL Gene

Variant ID Type Subtype PubMed ID
esv3572122 CNV loss 25503493
esv3891198 CNV gain 25118596

Variation tolerance for WASL Gene

Residual Variation Intolerance Score: 25.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.81; 17.00% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for WASL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
WASL
Leiden Open Variation Database (LOVD)
WASL

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for WASL Gene

Disorders for WASL Gene

MalaCards: The human disease database

(13) MalaCards diseases for WASL Gene - From: COP and GCD

Disorder Aliases PubMed IDs
wiskott-aldrich syndrome
  • was
buruli ulcer
  • buruli ulcer, susceptibility to
lower lip cancer
shigellosis
  • bacillary dysentery
myopathy, centronuclear, 2
  • cnm2
- elite association - COSMIC cancer census association via MalaCards
Search WASL in MalaCards View complete list of genes associated with diseases

Additional Disease Information for WASL

genes like me logo Genes that share disorders with WASL: view

No data available for UniProtKB/Swiss-Prot and Genatlas for WASL Gene

Publications for WASL Gene

  1. Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP. (PMID: 9422512) Miki H … Takenawa T (Nature 1998) 2 3 4 22
  2. Identification of N-WASP homologs in human and rat brain. (PMID: 9322739) Fukuoka M … Takenawa T (Gene 1997) 2 3 4 22
  3. Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners. (PMID: 16767080) Wu X … Guan JL (Nature cell biology 2006) 3 4 22
  4. The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins. (PMID: 16531231) Aguda AH … Robinson RC (Structure (London, England : 1993) 2006) 3 4 22
  5. Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading. (PMID: 24332715) Polle L … Schubert WD (Structure (London, England : 1993) 2014) 3 4

Products for WASL Gene

Sources for WASL Gene