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WASHC2C (WASH Complex Subunit 2C) is a Protein Coding gene. Diseases associated with WASHC2C include Vaccinia and Transient Tic Disorder. Among its related pathways are Endocytosis. An important paralog of this gene is WASHC2A.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 19922874 |
GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | IDA | 20498093 |
GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding | IDA | 20498093 |
GO:0008289 | lipid binding | IEA | -- |
GO:0010314 | phosphatidylinositol-5-phosphate binding | IDA | 20498093 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005730 | nucleolus | IDA | -- |
GO:0005768 | endosome | IDA | 20923837 |
GO:0005769 | early endosome | IDA | 19922874 |
GO:0005829 | cytosol | IDA | -- |
GO:0005886 | plasma membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Endocytosis |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0015031 | protein transport | IEA | -- |
GO:0036010 | protein localization to endosome | IMP | 28892079 |
GO:0042147 | retrograde transport, endosome to Golgi | IMP | 19922874 |
GO:1900024 | regulation of substrate adhesion-dependent cell spreading | IDA | 22070227 |
GO:1990126 | retrograde transport, endosome to plasma membrane | IMP | 25278552 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | LOC738985 30 |
|
||
FAM21C 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | LOC477751 30 |
|
||
-- 31 |
|
OneToMany | |||
Cow (Bos Taurus) |
Mammalia | FAM21A 30 |
|
||
-- 31 |
|
OneToMany | |||
Mouse (Mus musculus) |
Mammalia | Fam21 30 31 |
|
OneToMany | |
Washc2 17 |
|
||||
Rat (Rattus norvegicus) |
Mammalia | Fam21c 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | FAM21A 30 31 |
|
OneToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | fam21a 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | fam21c 30 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv114e214 | CNV | gain | 21293372 |
esv23760 | CNV | gain+loss | 19812545 |
esv2852680 | CNV | deletion | 24192839 |
esv33964 | CNV | loss | 17666407 |
nsv1076365 | CNV | duplication | 25765185 |
nsv1118164 | CNV | deletion | 24896259 |
nsv499498 | OTHER | inversion | 21111241 |
nsv7202 | OTHER | inversion | 18451855 |
nsv947914 | CNV | duplication | 23825009 |
nsv947915 | CNV | duplication | 23825009 |
nsv947916 | CNV | duplication | 23825009 |
nsv947917 | CNV | duplication | 23825009 |
Disorder | Aliases | PubMed IDs |
---|---|---|
vaccinia |
|
|
transient tic disorder |
|
|