Aliases for VTI1B Gene
External Ids for VTI1B Gene
Previous GeneCards Identifiers for VTI1B Gene
GeneCards Summary for VTI1B Gene
VTI1B (Vesicle Transport Through Interaction With T-SNAREs 1B) is a Protein Coding gene. Diseases associated with VTI1B include Hypomyelinating Leukodystrophy. Among its related pathways are wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include SNARE binding and chloride channel inhibitor activity. An important paralog of this gene is VTI1A.
UniProtKB/Swiss-Prot for VTI1B Gene
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.