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VPS37B (VPS37B Subunit Of ESCRT-I) is a Protein Coding gene. Among its related pathways are Budding and maturation of HIV virion and Endocytosis. Gene Ontology (GO) annotations related to this gene include calcium-dependent protein binding. An important paralog of this gene is VPS37C.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 15218037 |
GO:0048306 | calcium-dependent protein binding | IPI | 23924735 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000813 | ESCRT I complex | IEA,TAS | 20588296 |
GO:0005737 | cytoplasm | IDA | 15218037 |
GO:0005768 | endosome | IEA,IDA | 17940959 |
GO:0005886 | plasma membrane | IDA | 17940959 |
GO:0010008 | endosome membrane | IDA,TAS | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | HIV Life Cycle |
.91
.65
|
.45
|
2 | Budding and maturation of HIV virion | ||
3 | Vesicle-mediated transport | ||
4 | Endocytosis |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006612 | protein targeting to membrane | IBA | 21873635 |
GO:0006623 | protein targeting to vacuole | IBA | 21873635 |
GO:0015031 | protein transport | IEA | -- |
GO:0016197 | endosomal transport | TAS | -- |
GO:0016236 | macroautophagy | TAS | 20588296 |
ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||
SP2: | - | ||||||||||||
SP3: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | VPS37B 30 |
|
||
Dog (Canis familiaris) |
Mammalia | VPS37B 30 |
|
||
Cow (Bos Taurus) |
Mammalia | VPS37B 30 |
|
||
Rat (Rattus norvegicus) |
Mammalia | Vps37b 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Vps37b 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | VPS37B 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | VPS37B 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | VPS37B 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | VPS37B 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | vps37b 30 |
|
||
MGC75912 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | flj12750-prov 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | zgc:114173 30 |
|
||
vps37b 31 |
|
OneToMany | |||
VPS37B (1 of 2) 31 |
|
OneToMany | |||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP003731 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG1115 30 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | vps-37 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10674 31 |
|
OneToMany |
No disorders were found for VPS37B Gene.