Aliases for VPS28 Gene
External Ids for VPS28 Gene
Previous GeneCards Identifiers for VPS28 Gene
This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
GeneCards Summary for VPS28 Gene
VPS28 (VPS28 Subunit Of ESCRT-I) is a Protein Coding gene. Diseases associated with VPS28 include Tick Paralysis and Frontotemporal Dementia, Chromosome 3-Linked. Among its related pathways are Budding and maturation of HIV virion and Endocytosis. Gene Ontology (GO) annotations related to this gene include ubiquitin binding.
UniProtKB/Swiss-Prot Summary for VPS28 Gene
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.