The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar h... See more...

Aliases for VLDLR Gene

Aliases for VLDLR Gene

  • Very Low Density Lipoprotein Receptor 2 3 5
  • Very Low-Density Lipoprotein Receptor 3 4
  • VLDL Receptor 3 4
  • VLDLRCH 2 3
  • CARMQ1 2 3
  • CHRMQ1 2 3
  • VLDL-R 3 4
  • CAMRQ1 3
  • VLDLR 5

External Ids for VLDLR Gene

Previous GeneCards Identifiers for VLDLR Gene

  • GC09P002776
  • GC09P002603
  • GC09P002612

Summaries for VLDLR Gene

Entrez Gene Summary for VLDLR Gene

  • The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]

GeneCards Summary for VLDLR Gene

VLDLR (Very Low Density Lipoprotein Receptor) is a Protein Coding gene. Diseases associated with VLDLR include Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 1 and Cerebellar Hypoplasia. Among its related pathways are Lipoprotein metabolism and Guidance Cues and Growth Cone Motility. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is LDLR.

UniProtKB/Swiss-Prot Summary for VLDLR Gene

  • Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).

Gene Wiki entry for VLDLR Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for VLDLR Gene

Genomics for VLDLR Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for VLDLR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J002620 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 610.1 +1.0 992 4.4 HNRNPL GATAD2A PRDM10 TFE3 RFX1 KDM1A BACH1 LARP7 RBFOX2 POLR2A VLDLR VLDLR-AS1 piR-54979 KCNV2
GH09J002418 Enhancer 0.8 Ensembl ENCODE 42.5 -203.0 -202985 2 ATF7 PRDM10 ZIC2 ZBTB44 OSR2 CREB1 ATF2 WT1 ZNF513 FEZF1 VLDLR LOC105375956 piR-33863-145 lnc-VLDLR-2 LOC101930053 VLDLR-AS1 SMARCA2
GH09J002411 Enhancer 0.7 Ensembl ENCODE 37.2 -208.9 -208915 3.6 TEAD4 USF1 PKNOX1 CUX1 GATA3 DPF2 FOXA1 JUND RAD51 FOS VLDLR LOC105375956 piR-33863-145 lnc-VLDLR-2 LOC101930053 VLDLR-AS1 SMARCA2
GH09J002725 Enhancer 1.1 Ensembl ENCODE 11 +105.2 105214 3.6 CTCF ZNF629 ZNF692 FOXA1 ZNF143 PKNOX1 RXRB REST RAD21 RCOR1 VLDLR-AS1 VLDLR KCNV2 lnc-PUM3-3 piR-56785 PUM3
GH09J002654 Enhancer 0.9 FANTOM5 Ensembl ENCODE 11.7 +34.8 34777 3.7 POLR2A CEBPB JUND RUNX3 FOS SPI1 EBF1 REST JUN MYC VLDLR ENSG00000286670 LOC105375957 KCNV2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around VLDLR on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for VLDLR

Top Transcription factor binding sites by QIAGEN in the VLDLR gene promoter:
  • AML1a
  • AP-2gamma
  • Arnt
  • FosB
  • HSF2
  • ISGF-3
  • NCX
  • S8
  • USF-1
  • USF1

Genomic Locations for VLDLR Gene

Genomic Locations for VLDLR Gene
chr9:2,621,786-2,660,056
(GRCh38/hg38)
Size:
38,271 bases
Orientation:
Plus strand
chr9:2,621,793-2,660,053
(GRCh37/hg19)
Size:
38,261 bases
Orientation:
Plus strand

Genomic View for VLDLR Gene

Genes around VLDLR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
VLDLR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for VLDLR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VLDLR Gene

Proteins for VLDLR Gene

  • Protein details for VLDLR Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P98155-VLDLR_HUMAN
    Recommended name:
    Very low-density lipoprotein receptor
    Protein Accession:
    P98155
    Secondary Accessions:
    • B2RMZ7
    • D3DRH6
    • Q5VVF6

    Protein attributes for VLDLR Gene

    Size:
    873 amino acids
    Molecular mass:
    96098 Da
    Quaternary structure:
    • Binds to the extracellular matrix protein Reelin. Interacts with VLDLR. Interacts with SNX17 (By similarity). Interacts with DAB1. Receptor for the minor-group human rhinoviruses (HRVs); binds protein VP1 through the second and third LDL-receptor class A domains. Interacts with PCSK9.

    Three dimensional structures from OCA and Proteopedia for VLDLR Gene

    Alternative splice isoforms for VLDLR Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for VLDLR Gene

Post-translational modifications for VLDLR Gene

  • Ubiquitinated at Lys-839 by MYLIP leading to degradation.
  • Glycosylation at Thr71, Asn151, Thr277, Asn781, and Asn765
  • Ubiquitination at Lys828 and Lys839
  • Modification sites at PhosphoSitePlus

Other Protein References for VLDLR Gene

Protein Products

  • Novus Biologicals lysates for VLDLR
  • Signalway Proteins for VLDLR

No data available for DME Specific Peptides for VLDLR Gene

Domains & Families for VLDLR Gene

Gene Families for VLDLR Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for VLDLR Gene

InterPro:
Blocks:
  • Aspartic acid and asparagine hydroxylation site
  • EGF-like calcium-binding
  • Low density lipoprotein-receptor, class A
  • Low-density lipoprotein receptor, YWTD repeat
ProtoNet:

Suggested Antigen Peptide Sequences for VLDLR Gene

GenScript: Design optimal peptide antigens:
  • Very low density lipoprotein receptor, isoform CRA_a (Q5VVF5_HUMAN)
  • Very low density lipoprotein receptor (Q5VVF8_HUMAN)
  • cDNA FLJ35062 fis, clone OCBBF2019195, highly similar to VERY LOW-DENSITY LIPOPROTEIN RECEPTOR (Q8NAN7_HUMAN)
  • Very low-density lipoprotein receptor (VLDLR_HUMAN)
genes like me logo Genes that share domains with VLDLR: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for VLDLR Gene

Function for VLDLR Gene

Molecular function for VLDLR Gene

UniProtKB/Swiss-Prot Function:
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
GENATLAS Biochemistry:
very low density lipoprotein/ApoE receptor,containing a CGG repeat in 5'utr,(may be a susceptibility gene for late onset senile Alzheimer disease)

Phenotypes From GWAS Catalog for VLDLR Gene

Gene Ontology (GO) - Molecular Function for VLDLR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005041 low-density lipoprotein particle receptor activity TAS 10380922
GO:0005509 calcium ion binding IEA --
GO:0005515 protein binding IPI 8083232
GO:0030229 very-low-density lipoprotein particle receptor activity TAS 20005821
GO:0034185 apolipoprotein binding ISS --
genes like me logo Genes that share ontologies with VLDLR: view
genes like me logo Genes that share phenotypes with VLDLR: view

Human Phenotype Ontology for VLDLR Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for VLDLR Gene

MGI Knock Outs for VLDLR:

Animal Model Products

  • Taconic Biosciences Mouse Models for VLDLR

CRISPR Products

miRNA for VLDLR Gene

miRTarBase miRNAs that target VLDLR

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for VLDLR

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for VLDLR Gene

Localization for VLDLR Gene

Subcellular locations from UniProtKB/Swiss-Prot for VLDLR Gene

Membrane. Single-pass type I membrane protein. Membrane, clathrin-coated pit. Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for VLDLR gene
Compartment Confidence
plasma membrane 5
extracellular 4
lysosome 4
cytoskeleton 3
mitochondrion 2
peroxisome 2
nucleus 2
endoplasmic reticulum 2
endosome 2
cytosol 2
golgi apparatus 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centriolar satellite (2)
  • Cytokinetic bridge (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for VLDLR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IEA --
GO:0005765 lysosomal membrane TAS --
GO:0005886 plasma membrane TAS --
GO:0005905 clathrin-coated pit IEA --
GO:0016020 membrane IDA 15082773
genes like me logo Genes that share ontologies with VLDLR: view

Pathways & Interactions for VLDLR Gene

genes like me logo Genes that share pathways with VLDLR: view

Pathways by source for VLDLR Gene

1 KEGG pathway for VLDLR Gene
2 Qiagen pathways for VLDLR Gene
  • Guidance Cues and Growth Cone Motility
  • Reelin Pathway (Cajal-Retzius cells)

SIGNOR curated interactions for VLDLR Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for VLDLR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process IEA --
GO:0006869 lipid transport IEA --
GO:0006897 endocytosis IEA --
GO:0006898 receptor-mediated endocytosis IDA 10571240
GO:0007165 signal transduction TAS 10380922
genes like me logo Genes that share ontologies with VLDLR: view

Drugs & Compounds for VLDLR Gene

(10) Drugs for VLDLR Gene - From: DrugBank and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
lauric acid Approved, Experimental Pharma Agonist, Target 0
Tocopherol Approved, Investigational Pharma Carrier, binder 9,535
alpha-Tocopherol acetate Approved, Vet_approved Nutra Carrier, binder 0
Beta carotene Approved Nutra Carrier, substrate 72
Coenzyme Q10 Approved, Investigational Nutra Carrier, substrate 182

(6) Additional Compounds for VLDLR Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with VLDLR: view

Transcripts for VLDLR Gene

mRNA/cDNA for VLDLR Gene

4 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for VLDLR

Alternative Splicing Database (ASD) splice patterns (SP) for VLDLR Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b ·
SP1: - - -
SP2: -
SP3:
SP4: -
SP5: -
SP6: -
SP7:
SP8:
SP9:

ExUns: 16c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:

Relevant External Links for VLDLR Gene

GeneLoc Exon Structure for
VLDLR

Expression for VLDLR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for VLDLR Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for VLDLR Gene

This gene is overexpressed in Ovary (x5.6) and Heart - Left Ventricle (x5.4).

Protein differential expression in normal tissues from HIPED for VLDLR Gene

This gene is overexpressed in Adrenal (33.2) and Testis (15.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for VLDLR Gene



Protein tissue co-expression partners for VLDLR Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for VLDLR

SOURCE GeneReport for Unigene cluster for VLDLR Gene:

Hs.370422

mRNA Expression by UniProt/SwissProt for VLDLR Gene:

P98155-VLDLR_HUMAN
Tissue specificity: Abundant in heart and skeletal muscle; also ovary and kidney; not in liver.

Evidence on tissue expression from TISSUES for VLDLR Gene

  • Heart(4.6)
  • Muscle(4.6)
  • Nervous system(4.3)
  • Kidney(2.6)
  • Blood(2.5)
  • Liver(2.4)
  • Eye(2.3)
  • Skin(2.2)
  • Intestine(2.1)
  • Adrenal gland(2.1)
  • Pancreas(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for VLDLR Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • eye
  • face
  • head
  • jaw
  • lip
  • mandible
  • maxilla
  • mouth
  • neck
  • skull
Thorax:
  • lung
  • rib
  • rib cage
Pelvis:
  • pelvis
Limb:
  • foot
  • hand
  • lower limb
  • upper limb
General:
  • hair
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal column
  • spinal cord
  • vertebrae
genes like me logo Genes that share expression patterns with VLDLR: view

Orthologs for VLDLR Gene

This gene was present in the common ancestor of animals.

Orthologs for VLDLR Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia VLDLR 30 31
  • 99.62 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia VLDLR 30 31
  • 91.56 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia VLDLR 30 31
  • 91.16 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Vldlr 30
  • 91.07 (n)
Mouse
(Mus musculus)
Mammalia Vldlr 30 17 31
  • 90.95 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia VLDLR 31
  • 90 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia VLDLR 31
  • 71 (a)
OneToOne
Chicken
(Gallus gallus)
Aves VLDL 31
  • 80 (a)
OneToOne
VLDLR 30
  • 79.1 (n)
Lizard
(Anolis carolinensis)
Reptilia VLDLR 31
  • 71 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia vldlr 30
  • 72.39 (n)
Str.8622 30
African clawed frog
(Xenopus laevis)
Amphibia Xl.998 30
Zebrafish
(Danio rerio)
Actinopterygii vldlr 30 31
  • 68.57 (n)
OneToOne
zgc55792 30
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11520 30
Fruit Fly
(Drosophila melanogaster)
Insecta LpR1 30 31
  • 51.1 (n)
ManyToMany
CG4861 32
  • 40 (a)
LpR2 31
  • 33 (a)
ManyToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002186 30
  • 50.34 (n)
Worm
(Caenorhabditis elegans)
Secernentea T13C2.6 30 31
  • 50.53 (n)
OneToMany
R01H2.3 32
  • 38 (a)
B0244.8 32
  • 37 (a)
Species where no ortholog for VLDLR was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for VLDLR Gene

ENSEMBL:
Gene Tree for VLDLR (if available)
TreeFam:
Gene Tree for VLDLR (if available)
Aminode:
Evolutionary constrained regions (ECRs) for VLDLR: view image

Paralogs for VLDLR Gene

Paralogs for VLDLR Gene

(17) SIMAP similar genes for VLDLR Gene using alignment to 3 proteins:

  • VLDLR_HUMAN
  • Q5VVF5_HUMAN
  • Q5VVF8_HUMAN

Pseudogenes.org Pseudogenes for VLDLR Gene

genes like me logo Genes that share paralogs with VLDLR: view

Variants for VLDLR Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for VLDLR Gene

SNP ID Clinical significance and condition Chr 09 pos Variation AA Info Type
667580 Benign: not provided 2,621,482(+) C/G
667581 Benign: not provided 2,622,547(+) C/T INTRON_VARIANT
667582 Benign: not provided 2,622,554(+) T/C INTRON_VARIANT
667583 Benign: not provided 2,635,116(+) G/C INTRON_VARIANT
670830 Benign: not provided 2,644,543(+) G/A INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for VLDLR Gene

Structural Variations from Database of Genomic Variants (DGV) for VLDLR Gene

Variant ID Type Subtype PubMed ID
nsv1020530 CNV gain 25217958
nsv1029876 CNV gain 25217958
nsv1133705 CNV deletion 24896259
nsv527298 CNV loss 19592680
nsv613137 CNV gain 21841781
nsv824819 CNV gain 20364138

Variation tolerance for VLDLR Gene

Residual Variation Intolerance Score: 13% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.66; 65.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for VLDLR Gene

Human Gene Mutation Database (HGMD)
VLDLR
SNPedia medical, phenotypic, and genealogical associations of SNPs for
VLDLR

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VLDLR Gene

Disorders for VLDLR Gene

MalaCards: The human disease database

(23) MalaCards diseases for VLDLR Gene - From: OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

UniProtKB/Swiss-Prot

VLDLR_HUMAN
  • Cerebellar ataxia, mental retardation, and dysequilibrium syndrome 1 (CAMRQ1) [MIM:224050]: A congenital, non-progressive cerebellar ataxia associated with disturbed equilibrium, delayed ambulation, mental retardation, cerebellar hypoplasia and mild cerebral gyral simplification. Additional features include short stature, strabismus, pes planus and, rarely, seizures. {ECO:0000269 PubMed:16080122}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for VLDLR

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with VLDLR: view

No data available for Genatlas for VLDLR Gene

Publications for VLDLR Gene

  1. Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene. (PMID: 8294473) Sakai J … Yamamoto T (The Journal of biological chemistry 1994) 2 3 4 23
  2. The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2. (PMID: 18039658) Poirier S … Seidah NG (The Journal of biological chemistry 2008) 3 4 23
  3. A common VLDLR polymorphism interacts with APOE genotype in the prediction of carotid artery disease risk. (PMID: 18056683) Crawford DC … Jarvik GP (Journal of lipid research 2008) 3 23 41
  4. Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6. (PMID: 16384981) Haines JL … Pericak-Vance MA (Investigative ophthalmology & visual science 2006) 3 23 41
  5. Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification. (PMID: 16080122) Boycott KM … Parboosingh JS (American journal of human genetics 2005) 3 4 23

Products for VLDLR Gene

  • Addgene plasmids for VLDLR
  • Signalway ELISA kits for VLDLR
  • Signalway Proteins for VLDLR

Sources for VLDLR Gene