Aliases for VEGFD Gene
Aliases for VEGFD Gene
External Ids for VEGFD Gene
- HGNC: 3708
- Entrez Gene: 2277
- Ensembl: ENSG00000165197
- OMIM: 300091
- UniProtKB: O43915
Previous HGNC Symbols for VEGFD Gene
- FIGF
Summaries for VEGFD Gene
-
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]
GeneCards Summary for VEGFD Gene
VEGFD (Vascular Endothelial Growth Factor D) is a Protein Coding gene. Diseases associated with VEGFD include Breast Ductal Carcinoma and Anal Canal Squamous Cell Carcinoma. Among its related pathways are ERK Signaling and Focal Adhesion. An important paralog of this gene is VEGFC.
UniProtKB/Swiss-Prot for VEGFD Gene
-
Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Additional gene information for VEGFD Gene
- Monarch Initiative
- Search for VEGFD at DataMed
- Search for VEGFD at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VEGFD Gene
Genomics for VEGFD Gene
GeneHancer (GH) Regulatory Elements for VEGFD Gene
Promoters and enhancers for VEGFD Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH0XJ015384 | Promoter | 0.9 | EPDnew | 650.7 | -0.1 | -111 | 0.1 | RXRA MAX CEBPB CEBPG RAD21 YY1 NR2F2 SP1 CEBPA HNF4G | VEGFD BMX PIR-FIGF | |
| GH0XJ015385 | Promoter | 0.8 | EPDnew | 650.7 | +0.0 | 47 | 0.1 | RXRA CEBPB HNF4G MAX RAD21 YY1 NR2F2 | VEGFD PIGA PIR-FIGF | |
| GH0XJ015492 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 5.4 | -108.7 | -108723 | 2.2 | PKNOX1 ATF1 ARNT ARID4B SIN3A ZNF48 YY1 FOS ATF7 SP3 | PIR PIR-FIGF VEGFD BMX | |
| GH0XJ015789 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 5.2 | -406.5 | -406479 | 2.6 | HDGF PKNOX1 ATF1 ARNT ARID4B SIN3A ZNF2 YY1 POLR2B ZNF143 | ZRSR2 CA5B CA5BP1 VEGFD GC0XP015773 AP1S2 | |
| GH0XJ015737 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE | 5.2 | -353.9 | -353884 | 2.2 | HDGF PKNOX1 SIN3A YY1 GLIS2 ZNF143 KLF13 SP3 NCOA1 ZNF518A | CA5B CLTRN CA5BP1 ENSG00000200620 VEGFD GC0XP015773 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around VEGFD on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for VEGFD Gene
Genomic Locations for VEGFD Gene
- chrX:15,345,591-15,384,413
- (GRCh38/hg38)
- Size:
- 38,823 bases
- Orientation:
- Minus strand
- chrX:15,363,713-15,402,535
- (GRCh37/hg19)
- Size:
- 38,823 bases
- Orientation:
- Minus strand
Genomic View for VEGFD Gene
Genes around VEGFD on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.2 by Entrez Gene
- Xp22.2 by HGNC
- Xp22.2 by Ensembl
VEGFD Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for VEGFD Gene
Proteins for VEGFD Gene
-
Protein details for VEGFD Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43915-VEGFD_HUMAN
- Recommended name:
- Vascular endothelial growth factor D
- Protein Accession:
- O43915
- B2R7Z3
Protein attributes for VEGFD Gene
- Size:
- 354 amino acids
- Molecular mass:
- 40444 Da
- Quaternary structure:
-
- Homodimer; non-covalent and antiparallel.
Post-translational modifications for VEGFD Gene
- Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for VEGFD Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for VEGFD (VEGF-D)
-
Custom Antibody ServicesOriGene Antibodies for VEGFD
- Novus Biologicals Antibodies for VEGFD
-
Abcam antibodies for VEGFD
- Invitrogen Antibodies for VEGFD (AFLGC-VEGFD)
- GeneTex VEGFD Antibody for VEGFD
- Sino Biological Antibodies for VEGFD
Protein Products
- R&D Systems Proteins and Enzymes for VEGFD (VEGF-D)
-
OriGene Purified Proteins for VEGFD
- Search Origene for MassSpec and Protein Over-expression Lysates for VEGFD
- Origene Custom Protein Services for VEGFD
- Sino Biological Recombinant Proteins for VEGFD
- Sino Biological Cell Lysates for VEGFD
- ProSpec Recombinant Proteins for VEGFD
- GeneTex Proteins for VEGFD
-
Abcam proteins for VEGFD
No data available for DME Specific Peptides for VEGFD Gene
Domains & Families for VEGFD Gene
Gene Families for VEGFD Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for VEGFD Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for VEGFD Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O43915- Family:
-
- Belongs to the PDGF/VEGF growth factor family.
Function for VEGFD Gene
Molecular function for VEGFD Gene
- UniProtKB/Swiss-Prot Function:
- Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005161 | platelet-derived growth factor receptor binding | TAS | 9479493 |
| GO:0005172 | vascular endothelial growth factor receptor binding | IPI | 9435229 |
| GO:0005515 | protein binding | IPI | 27107012 |
| GO:0008083 | growth factor activity | IBA | -- |
| GO:0042056 | chemoattractant activity | IDA | 19275959 |
Phenotypes for VEGFD Gene
- MGI mutant phenotypes for VEGFD:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for VEGFD:
-
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased viability
- no effect
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
- Synthetic lethal with vaccinia virus (VACV) infection
Animal Model Products
-
Taconic Biosciences Mouse Models for VEGFD
- Cyagen custom Knockout/knockin (KOKI) mouse models for VEGFD
-
CRISPR Products
-
OriGene CRISPR knockouts for VEGFD
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for VEGFD
- genomics-online: gRNA clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
- Applied Biological Materials CRISPR for VEGFD
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for VEGFD
miRNA for VEGFD Gene
- miRTarBase miRNAs that target VEGFD
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for VEGFD
- Browse OriGene Inhibitory RNA Products For VEGFD
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for VEGFD
- genomics-online: shRNA clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
Clone Products
- Sino Biological Human cDNA Clone for VEGFD
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for VEGFD
- Applied Biological Materials Clones for VEGFD
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for VEGFD
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for VEGFD Gene
Localization for VEGFD Gene
Subcellular locations from UniProtKB/Swiss-Prot for VEGFD Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| nucleus | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | IEA,IBA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0031093 | platelet alpha granule lumen | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for VEGFD Gene
Pathways & Interactions for VEGFD Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Apoptotic Pathways in Synovial Fibroblasts |
.74
.66
|
.65
.61
.60
.57
|
| 2 | GPCR Pathway |
.73
.62
|
.55
|
| 3 | TGF-Beta Pathway |
.60
.57
|
.51
.40
|
| 4 | ERK Signaling |
.61
.58
|
.49
|
| 5 | Nanog in Mammalian ESC Pluripotency |
.61
|
.48
|
Pathways by source for VEGFD Gene
2 BioSystems pathways for VEGFD Gene
8 Reactome pathways for VEGFD Gene
8 KEGG pathways for VEGFD Gene
1 GeneGo (Thomson Reuters) pathway for VEGFD Gene
Interacting Proteins for VEGFD Gene
Selected Interacting proteins:
O43915-VEGFD_HUMAN
ENSP00000297904
for VEGFD Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for VEGFD
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001525 | angiogenesis | IBA | -- |
| GO:0001666 | response to hypoxia | IBA | -- |
| GO:0001938 | positive regulation of endothelial cell proliferation | IBA | -- |
| GO:0002576 | platelet degranulation | TAS | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
Transcripts for VEGFD Gene
mRNA/cDNA for VEGFD Gene
- (1) REFSEQ mRNAs :
- (27) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000297904 2037 bps (uc004cwt.3)
- ENST00000488351 600 bps (uc064ycm.1)
CRISPR Products
-
OriGene CRISPR knockouts for VEGFD
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for VEGFD
- genomics-online: gRNA clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
- Applied Biological Materials CRISPR for VEGFD
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for VEGFD
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for VEGFD
- Browse OriGene Inhibitory RNA Products For VEGFD
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for VEGFD
- genomics-online: shRNA clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
Clone Products
- Sino Biological Human cDNA Clone for VEGFD
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for VEGFD
- Applied Biological Materials Clones for VEGFD
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for VEGFD Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Limb (Muscoskeletal System)
- Apical Ectodermal Ridge Cells Limb Ectoderm
- Limb Bud Mesenchyme Cells Limb Bud
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
-
Ectoderm (Gastrulation Derivatives)
- Apical Ectodermal Ridge Cells Limb Ectoderm
-
Mesoderm (Gastrulation Derivatives)
- Limb Bud Mesenchyme Cells Limb Bud
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
NURSA nuclear receptor signaling pathways regulating expression of VEGFD Gene:
VEGFDmRNA Expression by UniProt/SwissProt for VEGFD Gene:
O43915-VEGFD_HUMAN
Tissue specificity:
Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
Evidence on tissue expression from TISSUES for VEGFD Gene
- Lung(4.5)
- Heart(2.8)
- Lymph node(2.6)
- Muscle(2.1)
- Nervous system(2)
Primer Products
-
OriGene qPCR primer pairs for VEGFD
-
OriGene qPCR primer pairs and template standards for VEGFD
- genomics-online: primer clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for VEGFD Gene
Orthologs for VEGFD Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FIGF 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | FIGF 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | FIGF 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Figf 34 33 |
|
OneToOne | |
| Vegfd 16 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | Figf 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FIGF 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | FIGF 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FIGF 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FIGF 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | figf 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | figf 34 33 |
|
OneToOne |
- Species where no ortholog for VEGFD was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for VEGFD Gene
- ENSEMBL:
- Gene Tree for VEGFD (if available)
- TreeFam:
- Gene Tree for VEGFD (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for VEGFD: view image
Paralogs for VEGFD Gene
Variants for VEGFD Gene
| SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000334250 | -- | 15,356,973(-) | T/C | intron_variant | |
| rs1000386455 | -- | 15,356,388(-) | AAAAAA/AAAAAAA | intron_variant | |
| rs1000438451 | -- | 15,365,157(-) | G/A | intron_variant | |
| rs1000486561 | -- | 15,357,552(-) | C/T | intron_variant | |
| rs1000489001 | -- | 15,363,549(-) | A/G | intron_variant |
Residual Variation Intolerance Score:
56.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.35;
41.83% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for VEGFD Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- VEGFD
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VEGFD Gene
Disorders for VEGFD Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| breast ductal carcinoma |
|
|
| anal canal squamous cell carcinoma |
|
|
| lymphangioleiomyomatosis |
|
|
| congenital lymphedema |
|
|
| breast cancer |
|
Search VEGFD in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for VEGFD
No data available for UniProtKB/Swiss-Prot and Genatlas for VEGFD Gene
Publications for VEGFD Gene
- Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes. (PMID: 9479493) Rocchigiani M … Oliviero S (Genomics 1998) 2 3 4 22 58
- Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers. (PMID: 10542248) Stacker SA … Achen MG (The Journal of biological chemistry 1999) 3 4 22 58
- Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). (PMID: 9435229) Achen MG … Stacker SA (Proceedings of the National Academy of Sciences of the United States of America 1998) 3 4 22 58
- Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. (PMID: 9205122) Yamada Y … Hirata Y (Genomics 1997) 3 4 22 58
- [Expression of VEGF-C and VEGF-D in gastric carcinoma and its relationship with lymph node metastases]. (PMID: 20448355) Wang W … Tang L (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2010) 3 22 58
Products for VEGFD Gene
- R&D Systems Antibodies for VEGFD (VEGF-D)
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- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Tissue Microarrays
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- ProSpec Recombinant Proteins for VEGFD
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- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
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- antibodies-online: Search results for 168 available FIGF Antibodies ranked by validation data
- Compare Top FIGF Antibodies
- antibodies-online: Search results for 55 available FIGF Elisa Kits ranked by validation data
- Compare Top FIGF Elisa Kits
- antibodies-online: Search results for 36 available FIGF Proteins ranked by validation data
- Compare Top FIGF Proteins
- GeneTex VEGFD Antibody for VEGFD
- GeneTex Proteins for VEGFD
- Horizon Cell Lines for VEGFD
- genomics-online: cdna clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
- orf clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
- genomics-online: gRNA clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
- genomics-online: primer clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
- genomics-online: shRNA clones - Search results for 118 available FIGF gene related products
- Overview of 118 available FIGF gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for VEGFD
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Sources for VEGFD Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
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