VDAC1P4 Gene (Pseudogene)

Voltage Dependent Anion Channel 1 Pseudogene 4

GC01P180434
GIFtS:
8
VDAC4 belongs to a family of small, abundant pore-forming proteins found in the outer mitochondrial membrane. These channels are thought to form the major pathway for movement of adenine nucleotides through the outer membrane and may also function as the mitochondrial binding site for hexokinase (see HK1; MIM 142600) and glycerol kinase (GK; MIM 300474) (Blachly-Dyson et al., 1... See more...

Aliases for VDAC1P4 Gene

Aliases for VDAC1P4 Gene

  • Voltage Dependent Anion Channel 1 Pseudogene 4 2 3 5
  • Voltage-Dependent Anion Channel 4 Pseudogene 2 3
  • Voltage-Dependent Anion Channel 4 2
  • VDAC1P4 5
  • VDAC4P 3
  • VDAC4 3

External Ids for VDAC1P4 Gene

Previous HGNC Symbols for VDAC1P4 Gene

  • VDAC4
  • VDAC4P

Previous GeneCards Identifiers for VDAC1P4 Gene

  • GC01U902394
  • GC01P180404
  • GC01P151634

Summaries for VDAC1P4 Gene

Entrez Gene Summary for VDAC1P4 Gene

  • VDAC4 belongs to a family of small, abundant pore-forming proteins found in the outer mitochondrial membrane. These channels are thought to form the major pathway for movement of adenine nucleotides through the outer membrane and may also function as the mitochondrial binding site for hexokinase (see HK1; MIM 142600) and glycerol kinase (GK; MIM 300474) (Blachly-Dyson et al., 1994 [PubMed 7517385]).[supplied by OMIM, Mar 2008]

GeneCards Summary for VDAC1P4 Gene

VDAC1P4 (Voltage Dependent Anion Channel 1 Pseudogene 4) is a Pseudogene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts.

Additional gene information for VDAC1P4 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for VDAC1P4 Gene

Genomics for VDAC1P4 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for VDAC1P4 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J180431 Enhancer 0.3 Ensembl 600.7 -1.7 -1695 3 CEBPB HLF VDAC1P4 ACBD6 LOC105371637 LHX4-AS1 LHX4
GH01J180434 Enhancer 0.2 FANTOM5 600.7 0.0 -44 0 VDAC1P4 LOC105371637 ACBD6 LHX4-AS1 LHX4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around VDAC1P4 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for VDAC1P4 Gene

Genomic Locations for VDAC1P4 Gene
chr1:180,434,796-180,436,802
(GRCh38/hg38)
Size:
2,007 bases
Orientation:
Plus strand
chr1:180,403,931-180,405,937
(GRCh37/hg19)
Size:
2,007 bases
Orientation:
Plus strand

Genomic View for VDAC1P4 Gene

Genes around VDAC1P4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
VDAC1P4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for VDAC1P4 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for VDAC1P4 Gene

Proteins for VDAC1P4 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for VDAC1P4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for VDAC1P4 Gene

Domains & Families for VDAC1P4 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for VDAC1P4 Gene

Function for VDAC1P4 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
genes like me logo Genes that share phenotypes with VDAC1P4: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for VDAC1P4 Gene

Localization for VDAC1P4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for VDAC1P4 Gene

Pathways & Interactions for VDAC1P4 Gene

PathCards logo

SuperPathways for VDAC1P4 Gene

SuperPathway Contained pathways
1 Apoptotic Pathways in Synovial Fibroblasts
Cellular Apoptosis Pathway
.85
Mitochondrial Apoptosis
.85
genes like me logo Genes that share pathways with VDAC1P4: view

Pathways by source for VDAC1P4 Gene

2 Qiagen pathways for VDAC1P4 Gene
  • Cellular Apoptosis Pathway
  • Mitochondrial Apoptosis

Gene Ontology (GO) - Biological Process for VDAC1P4 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for VDAC1P4 Gene

Drugs & Compounds for VDAC1P4 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for VDAC1P4 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for VDAC1P4 Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for VDAC1P4 Gene

No ASD Table

Relevant External Links for VDAC1P4 Gene

GeneLoc Exon Structure for
VDAC1P4

Expression for VDAC1P4 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for VDAC1P4 Gene

mRNA expression in normal human tissues for VDAC1P4 Gene
mRNA expression by GTEx for VDAC1P4 Gene
genes like me logo Genes that share expression patterns with VDAC1P4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for VDAC1P4 Gene

Orthologs for VDAC1P4 Gene

Evolution for VDAC1P4 Gene

ENSEMBL:
Gene Tree for VDAC1P4 (if available)
TreeFam:
Gene Tree for VDAC1P4 (if available)

No data available for Orthologs for VDAC1P4 Gene

Paralogs for VDAC1P4 Gene

No data available for Paralogs for VDAC1P4 Gene

Variants for VDAC1P4 Gene

Additional Variant Information for VDAC1P4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
VDAC1P4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for VDAC1P4 Gene

Disorders for VDAC1P4 Gene

No disorders were found for VDAC1P4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for VDAC1P4 Gene

Publications for VDAC1P4 Gene

  1. Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms. (PMID: 7517385) Blachly-Dyson E … Forte M (Genomics 1994) 2 3
  2. Utility of syntenic relationships of VDAC1 pseudogenes for not only an understanding of the phylogenetic divergence history of rodents, but also ascertaining possible pseudogene candidates as genuine pseudogenes. (PMID: 24858958) Ido Y … Shinohara Y (Genomics 2014) 3
  3. Further analysis of the involvement of the envelope anion channel PIRAC in chloroplast protein import. (PMID: 10849000) van den Wijngaard PW … Vredenberg WJ (European journal of biochemistry 2000) 23

ExternalLinks

View latest publications for VDAC1P4 gene in Mastermind

Products for VDAC1P4 Gene

Sources for VDAC1P4 Gene