Aliases for VARS1 Gene
External Ids for VARS1 Gene
Previous HGNC Symbols for VARS1 Gene
Previous GeneCards Identifiers for VARS1 Gene
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
GeneCards Summary for VARS1 Gene
VARS1 (Valyl-TRNA Synthetase 1) is a Protein Coding gene. Diseases associated with VARS1 include Neurodevelopmental Disorder With Microcephaly, Seizures, And Cortical Atrophy and Combined Oxidative Phosphorylation Deficiency 20. Among its related pathways are tRNA Aminoacylation and Amino Acid metabolism. An important paralog of this gene is VARS2.