Aliases for VARS Gene
External Ids for VARS Gene
Previous HGNC Symbols for VARS Gene
Previous GeneCards Identifiers for VARS Gene
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
GeneCards Summary for VARS Gene
VARS (Valyl-TRNA Synthetase) is a Protein Coding gene. Diseases associated with VARS include Neurodevelopmental Disorder With Microcephaly, Seizures, And Cortical Atrophy. Among its related pathways are Gene Expression and tRNA Aminoacylation. Gene Ontology (GO) annotations related to this gene include nucleotide binding and aminoacyl-tRNA editing activity. An important paralog of this gene is VARS2.