Aliases for VAMP4 Gene
External Ids for VAMP4 Gene
Previous GeneCards Identifiers for VAMP4 Gene
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008]
GeneCards Summary for VAMP4 Gene
VAMP4 (Vesicle Associated Membrane Protein 4) is a Protein Coding gene. Diseases associated with VAMP4 include Chronic Interstitial Cystitis and Leukodystrophy, Hypomyelinating, 6. Among its related pathways are Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics and wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF). Gene Ontology (GO) annotations related to this gene include SNARE binding and SNAP receptor activity. An important paralog of this gene is ENSG00000263620.
UniProtKB/Swiss-Prot Summary for VAMP4 Gene
Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.