Aliases for VAMP3 Gene
External Ids for VAMP3 Gene
Previous GeneCards Identifiers for VAMP3 Gene
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]
GeneCards Summary for VAMP3 Gene
VAMP3 (Vesicle Associated Membrane Protein 3) is a Protein Coding gene. Diseases associated with VAMP3 include Tetanus. Among its related pathways are Retrograde transport at the Trans-Golgi-Network and Clathrin-mediated endocytosis. Gene Ontology (GO) annotations related to this gene include SNARE binding and syntaxin-1 binding. An important paralog of this gene is ENSG00000263620.
UniProtKB/Swiss-Prot Summary for VAMP3 Gene
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.