Aliases for VAMP1 Gene
External Ids for VAMP1 Gene
Previous HGNC Symbols for VAMP1 Gene
Previous GeneCards Identifiers for VAMP1 Gene
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]
GeneCards Summary for VAMP1 Gene
VAMP1 (Vesicle Associated Membrane Protein 1) is a Protein Coding gene. Diseases associated with VAMP1 include Spastic Ataxia 1, Autosomal Dominant and Presynaptic Congenital Myasthenic Syndromes. Among its related pathways are Uptake and actions of bacterial toxins and Sertoli-Sertoli Cell Junction Dynamics. Gene Ontology (GO) annotations related to this gene include SNARE binding and SNAP receptor activity. An important paralog of this gene is VAMP2.
UniProtKB/Swiss-Prot for VAMP1 Gene
Involved in the targeting and/or fusion of transport vesicles to their target membrane.