This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of the... See more...

Aliases for UTY Gene

Aliases for UTY Gene

  • Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked 2 3 5
  • KDM6C 2 3 4
  • Ubiquitously-Transcribed Y Chromosome Tetratricopeptide Repeat Protein 3 4
  • Ubiquitously Transcribed Tetratricopeptide Repeat Gene, Y Chromosome 2 3
  • Ubiquitously Transcribed Tetratricopeptide Repeat Gene, Y-Linked 2 3
  • Ubiquitously-Transcribed TPR Protein On The Y Chromosome 3 4
  • [Histone H3]-Trimethyl-L-Lysine(27) Demethylase UTY 3 4
  • Histone Demethylase UTY 3 4
  • KDM6AL 2 3
  • Ubiquitously Transcribed TPR Gene On Y Chromosome 3
  • Ubiquitous TPR Motif Protein UTY 3
  • EC 1.14.11.68 4
  • EC 1.14.11 51
  • UTY1 3
  • UTY 5

External Ids for UTY Gene

Previous GeneCards Identifiers for UTY Gene

  • GC0YM014678
  • GC0YM014368
  • GC0YM013798
  • GC0YM015360
  • GC0YM010010

Summaries for UTY Gene

Entrez Gene Summary for UTY Gene

  • This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012]

GeneCards Summary for UTY Gene

UTY (Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked) is a Protein Coding gene. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include dioxygenase activity and histone demethylase activity (H3-K27 specific). An important paralog of this gene is KDM6A.

UniProtKB/Swiss-Prot Summary for UTY Gene

  • Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.

Gene Wiki entry for UTY Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for UTY Gene

Genomics for UTY Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for UTY Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0YJ013477 Enhancer 0.5 ENCODE 600.7 +1.4 1365 2.7 POLR2A USF1 YY1 SIN3A ZNF143 TAF1 TBP USF2 CEBPB MIR12120 UTY lnc-UTY-1 RF00017-8852 DDX3Y
GH0YJ013435 Enhancer 0.7 FANTOM5 ENCODE 0.3 +44.5 44450 1.8 IRF2 CTCF RAD21 KAT2B HLF NR2F6 TMSB4Y lnc-UTY-1 MIR12120 UTY L13714-504 RF00017-8853 RF00017-8852 DDX3Y
GH0YJ013475 Enhancer 0.3 ENCODE 0.4 +5.5 5487 0 JUN MIR12120 lnc-UTY-1 UTY L13714-504 RF00017-8852 DDX3Y
GH0YJ013359 Enhancer 0.3 UCNEbase 0.1 +121.5 121503 0.3 hsa-miR-5096-196 piR-32287-215 RF00017-8853 UTY lnc-UTY-1 RF00017-8852 DDX3Y
GH0YJ013663 Enhancer 0.3 ENCODE 0.1 -183.2 -183236 1 NANOG POU5F1 piR-32287-216 piR-38352-624 TMSB4Y UTY
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around UTY on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for UTY

Top Transcription factor binding sites by QIAGEN in the UTY gene promoter:
  • CBF(2)
  • CBF-A
  • CBF-B
  • CP1A
  • En-1
  • ER-alpha
  • FOXC1
  • NF-Y
  • NF-YA
  • NF-YB

Genomic Locations for UTY Gene

Genomic Locations for UTY Gene
chrY:13,231,827-13,480,673
(GRCh38/hg38)
Size:
248,847 bases
Orientation:
Minus strand
chrY:15,360,259-15,592,553
(GRCh37/hg19)
Size:
232,295 bases
Orientation:
Minus strand

Genomic View for UTY Gene

Genes around UTY on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UTY Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UTY Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTY Gene

Proteins for UTY Gene

  • Protein details for UTY Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O14607-UTY_HUMAN
    Recommended name:
    Histone demethylase UTY
    Protein Accession:
    O14607
    Secondary Accessions:
    • A8K9Z3
    • E1U199
    • E1U1A0
    • F5H4V7
    • F8W8R7
    • O14608

    Protein attributes for UTY Gene

    Size:
    1347 amino acids
    Molecular mass:
    149548 Da
    Cofactor:
    Name=L-ascorbate; Xref=ChEBI:CHEBI:38290;
    Cofactor:
    Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
    Quaternary structure:
    • Interacts with TLE1 and TLE2.

    Three dimensional structures from OCA and Proteopedia for UTY Gene

    Alternative splice isoforms for UTY Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UTY Gene

Selected DME Specific Peptides for UTY Gene

O14607:
  • GTCDKVNNIHP
  • ASSPSSAIST
  • DYWKNAAFLYGLGLVYF
  • QRPGDLVWINAGTVHWVQA
  • IGKVQDAF
  • GWCNNIAWNVGPLTA
  • DPNSGQSWYFLGRCYS
  • YQRYYSLQ
  • KLNPPTPSIYLE
  • SEASADTWCSIGVLYQQQNQP
  • FCRAKEIHLRLG
  • IKFGTNIDLSD
  • SFQESLREENE
  • SHTTIAKYAQYQA
  • VEVRTQLLQPADENWDP
  • EIQFHIAHLYETQRKYHSAK

Post-translational modifications for UTY Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Domains & Families for UTY Gene

Protein Domains for UTY Gene

InterPro:
Blocks:
  • Transcription factor jumonji, jmjC
ProtoNet:

Suggested Antigen Peptide Sequences for UTY Gene

GenScript: Design optimal peptide antigens:
  • Ubiquitously transcribed tetratricopeptide repeat Y-linked isoform 3 (C3UJR9_HUMAN)
  • Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 11 (E1NZ79_HUMAN)
  • Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 26 (E1NZ81_HUMAN)
  • Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 256 (E1NZ82_HUMAN)
  • Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 136 (E1NZ84_HUMAN)

Graphical View of Domain Structure for InterPro Entry

O14607

UniProtKB/Swiss-Prot:

UTY_HUMAN :
  • Belongs to the UTX family.
Family:
  • Belongs to the UTX family.
genes like me logo Genes that share domains with UTY: view

Function for UTY Gene

Molecular function for UTY Gene

UniProtKB/Swiss-Prot Function:
Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + 2 succinate; Xref=Rhea:RHEA:60224, Rhea:RHEA-COMP:15535, Rhea:RHEA-COMP:15544, ChEBI:CHEBI:15379, ChEBI:CHEBI:16526, ChEBI:CHEBI:16810, ChEBI:CHEBI:16842, ChEBI:CHEBI:30031, ChEBI:CHEBI:61929, ChEBI:CHEBI:61961; EC=1.14.11.68; Evidence={ECO:0000269|PubMed:24798337};.
GENATLAS Biochemistry:
ubiquitously transcribed tetratricopeptide repeat (TPR) gene on chromosome Y,with several alternatively spliced isoforms,ubiquitous in a AZF deleted region

Enzyme Numbers (IUBMB) for UTY Gene

Gene Ontology (GO) - Molecular Function for UTY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA 21873635
GO:0003682 chromatin binding IBA 21873635
GO:0005515 protein binding IEA --
GO:0016491 oxidoreductase activity IEA --
GO:0031490 chromatin DNA binding IBA 21873635
genes like me logo Genes that share ontologies with UTY: view
genes like me logo Genes that share phenotypes with UTY: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for UTY

Clone Products

  • Addgene plasmids for UTY

No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UTY Gene

Localization for UTY Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTY Gene

Nucleus.

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for UTY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IBA 21873635
GO:0005634 nucleus IBA 21873635
GO:0005654 nucleoplasm TAS --
GO:0044666 MLL3/4 complex IBA 21873635
genes like me logo Genes that share ontologies with UTY: view

No data available for Subcellular locations from COMPARTMENTS for UTY Gene

Pathways & Interactions for UTY Gene

genes like me logo Genes that share pathways with UTY: view

Pathways by source for UTY Gene

Interacting Proteins for UTY Gene

Gene Ontology (GO) - Biological Process for UTY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006325 chromatin organization IEA --
GO:0010468 regulation of gene expression IEA --
GO:0055114 oxidation-reduction process IEA --
GO:0071557 histone H3-K27 demethylation IEA --
genes like me logo Genes that share ontologies with UTY: view

No data available for SIGNOR curated interactions for UTY Gene

Drugs & Compounds for UTY Gene

No Compound Related Data Available

Transcripts for UTY Gene

mRNA/cDNA for UTY Gene

25 REFSEQ mRNAs :
295 NCBI additional mRNA sequence :
16 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for UTY

Clone Products

  • Addgene plasmids for UTY

Alternative Splicing Database (ASD) splice patterns (SP) for UTY Gene

No ASD Table

Relevant External Links for UTY Gene

GeneLoc Exon Structure for
UTY

Expression for UTY Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for UTY Gene

Protein differential expression in normal tissues from HIPED for UTY Gene

This gene is overexpressed in Pancreatic juice (41.7) and Heart (22.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for UTY Gene



Protein tissue co-expression partners for UTY Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for UTY

SOURCE GeneReport for Unigene cluster for UTY Gene:

Hs.115277
genes like me logo Genes that share expression patterns with UTY: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for UTY Gene

Orthologs for UTY Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UTY Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia UTY 31
  • 92 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 80 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 78 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Uty 31
  • 77 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia UTY 31
  • 75 (a)
OneToOne
Chicken
(Gallus gallus)
Aves -- 31
  • 77 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 73 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii kdm6a 31
  • 67 (a)
ManyToMany
kdm6al 31
  • 63 (a)
ManyToMany
Fruit Fly
(Drosophila melanogaster)
Insecta CG5640 32
  • 57 (a)
Utx 31
  • 43 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea D2021.1 32
  • 38 (a)
F18E9.5a 32
  • 31 (a)
F18E9.5b 32
  • 31 (a)
utx-1 31
  • 30 (a)
OneToMany
F23D12.5 32
  • 28 (a)
C29F7.6 32
  • 27 (a)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CYC8 31
  • 19 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.8580 31
  • 42 (a)
OneToMany
Species where no ortholog for UTY was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for UTY Gene

ENSEMBL:
Gene Tree for UTY (if available)
TreeFam:
Gene Tree for UTY (if available)
Aminode:
Evolutionary constrained regions (ECRs) for UTY: view image

Paralogs for UTY Gene

Paralogs for UTY Gene

(173) SIMAP similar genes for UTY Gene using alignment to 260 proteins:

  • UTY_HUMAN
  • A6NCS7_HUMAN
  • C3UJR9_HUMAN
  • E1NZ79_HUMAN
  • E1NZ81_HUMAN
  • E1NZ82_HUMAN
  • E1NZ84_HUMAN
  • E1NZ85_HUMAN
  • E1NZ86_HUMAN
  • E1NZ87_HUMAN
  • E1NZ88_HUMAN
  • E1NZ89_HUMAN
  • E1NZ90_HUMAN
  • E1NZ91_HUMAN
  • E1NZ92_HUMAN
  • E1NZ93_HUMAN
  • E1NZ94_HUMAN
  • E1NZ95_HUMAN
  • E1NZ96_HUMAN
  • E1NZ97_HUMAN
  • E1NZ98_HUMAN
  • E1NZ99_HUMAN
  • E1NZA0_HUMAN
  • E1U0S4_HUMAN
  • E1U198_HUMAN
  • E1U1M2_HUMAN
  • E1U1M3_HUMAN
  • E1U1M4_HUMAN
  • E1U1M5_HUMAN
  • E1U1M6_HUMAN
  • E1U1M7_HUMAN
  • E1U1M8_HUMAN
  • E1U1M9_HUMAN
  • E1U1N0_HUMAN
  • E1U1N1_HUMAN
  • F4MH27_HUMAN
  • F4MH28_HUMAN
  • F4MH29_HUMAN
  • F4MH30_HUMAN
  • F4MH31_HUMAN
  • F4MH32_HUMAN
  • F4MH33_HUMAN
  • F4MH34_HUMAN
  • F4MH35_HUMAN
  • F4MH36_HUMAN
  • F4MH37_HUMAN
  • F4MH38_HUMAN
  • F4MH39_HUMAN
  • F4MH40_HUMAN
  • F4MH41_HUMAN
  • F4MH42_HUMAN
  • F4MH43_HUMAN
  • F4MH44_HUMAN
  • F4MH45_HUMAN
  • F4MH46_HUMAN
  • F4MH47_HUMAN
  • F4MH48_HUMAN
  • F4MH49_HUMAN
  • F4MH50_HUMAN
  • F4MH51_HUMAN
  • F4MH52_HUMAN
  • F4MH53_HUMAN
  • F4MH54_HUMAN
  • F4MH55_HUMAN
  • F4MH56_HUMAN
  • F4MH57_HUMAN
  • F4MH58_HUMAN
  • F4MH59_HUMAN
  • F4MH60_HUMAN
  • F4MH61_HUMAN
  • F4MH62_HUMAN
  • F4MH63_HUMAN
  • F4MH64_HUMAN
  • F4MH65_HUMAN
  • F4MH66_HUMAN
  • F4MH67_HUMAN
  • F4MH68_HUMAN
  • F4MH69_HUMAN
  • F4MH70_HUMAN
  • F4MH73_HUMAN
  • F4MH74_HUMAN
  • F4MH75_HUMAN
  • F4MH77_HUMAN
  • F4MH78_HUMAN
  • F4MH79_HUMAN
  • F4MH81_HUMAN
  • F4MH82_HUMAN
  • F4MH83_HUMAN
  • F4MH84_HUMAN
  • F4MH86_HUMAN
  • F4MH87_HUMAN
  • F4MH88_HUMAN
  • F4MH89_HUMAN
  • F4MH90_HUMAN
  • F4MH91_HUMAN
  • F4MH92_HUMAN
  • F4MH93_HUMAN
  • F4MH94_HUMAN
  • F4MH97_HUMAN
  • F4MH98_HUMAN
  • F4MH99_HUMAN
  • F4MHA0_HUMAN
  • F4MHA2_HUMAN
  • F4MHA3_HUMAN
  • F4MHA4_HUMAN
  • F4MHA5_HUMAN
  • F4MHA6_HUMAN
  • F4MHA7_HUMAN
  • F4MHA8_HUMAN
  • F4MHA9_HUMAN
  • F4MHB1_HUMAN
  • F4MHB2_HUMAN
  • F4MHB3_HUMAN
  • F4MHB5_HUMAN
  • F4MHB6_HUMAN
  • F4MHB7_HUMAN
  • F4MHB8_HUMAN
  • F4MHB9_HUMAN
  • F4MHC0_HUMAN
  • F4MHC1_HUMAN
  • F4MHC2_HUMAN
  • F4MHC4_HUMAN
  • F4MHC6_HUMAN
  • F4MHC7_HUMAN
  • F4MHC8_HUMAN
  • F4MHC9_HUMAN
  • F4MHD0_HUMAN
  • F4MHD1_HUMAN
  • F4MHD2_HUMAN
  • F4MHD3_HUMAN
  • F4MHD4_HUMAN
  • F4MHD5_HUMAN
  • F4MHD6_HUMAN
  • F4MHD7_HUMAN
  • F4MHD8_HUMAN
  • F4MHD9_HUMAN
  • F4MHE0_HUMAN
  • F4MHE1_HUMAN
  • F4MHE4_HUMAN
  • F4MHE5_HUMAN
  • F4MHE6_HUMAN
  • F4MHE7_HUMAN
  • F4MHE8_HUMAN
  • F4MHE9_HUMAN
  • F4MHF0_HUMAN
  • F4MHF1_HUMAN
  • F4MHF2_HUMAN
  • F4MHF6_HUMAN
  • F4MHF7_HUMAN
  • F4MHF8_HUMAN
  • F4MHG0_HUMAN
  • F4MHG1_HUMAN
  • F4MHG2_HUMAN
  • F4MHG3_HUMAN
  • F4MHG4_HUMAN
  • F4MHG5_HUMAN
  • F4MHG6_HUMAN
  • F4MHG7_HUMAN
  • F4MHG8_HUMAN
  • F4MHG9_HUMAN
  • F4MHH0_HUMAN
  • F4MHH1_HUMAN
  • F4MHH2_HUMAN
  • F4MHH3_HUMAN
  • F4MHH4_HUMAN
  • F4MHH5_HUMAN
  • F4MHH6_HUMAN
  • F4MHH7_HUMAN
  • F4MHH8_HUMAN
  • F4MHH9_HUMAN
  • F4MHI0_HUMAN
  • F4MHI1_HUMAN
  • F4MHI2_HUMAN
  • F4MHI3_HUMAN
  • F4MHI4_HUMAN
  • F4MHI5_HUMAN
  • F4MHI6_HUMAN
  • F4MHI7_HUMAN
  • F4MHI8_HUMAN
  • F4MHI9_HUMAN
  • F4MHJ0_HUMAN
  • F4MHJ1_HUMAN
  • F4MHJ2_HUMAN
  • F4MHJ3_HUMAN
  • F4MHJ4_HUMAN
  • F4MHJ6_HUMAN
  • F4MHJ7_HUMAN
  • F4MHJ8_HUMAN
  • F4MHJ9_HUMAN
  • F4MHK0_HUMAN
  • F4MHK1_HUMAN
  • F4MHK2_HUMAN
  • F4MHK4_HUMAN
  • F4MHK5_HUMAN
  • F4MHK7_HUMAN
  • F4MHK8_HUMAN
  • F4MHK9_HUMAN
  • F4MHL1_HUMAN
  • F4MHL2_HUMAN
  • F4MHL4_HUMAN
  • F4MHL5_HUMAN
  • F4MHL6_HUMAN
  • F4MHL7_HUMAN
  • F4MHL8_HUMAN
  • F4MHL9_HUMAN
  • F4MHM0_HUMAN
  • F4MHM1_HUMAN
  • F4MHM2_HUMAN
  • F4MHM3_HUMAN
  • F4MHM4_HUMAN
  • F4MHM5_HUMAN
  • F4MHM6_HUMAN
  • F4MHM8_HUMAN
  • F4MHM9_HUMAN
  • F4MHN1_HUMAN
  • F4MHN2_HUMAN
  • F4MHN4_HUMAN
  • F4MHN5_HUMAN
  • F4MHN6_HUMAN
  • F4MHN7_HUMAN
  • F4MHP0_HUMAN
  • F4MHP1_HUMAN
  • F4MHP2_HUMAN
  • F4MHP3_HUMAN
  • F4MHP5_HUMAN
  • F4MHP6_HUMAN
  • F4MHP7_HUMAN
  • F4MHP8_HUMAN
  • F4MHP9_HUMAN
  • F4MHQ0_HUMAN
  • F4MHQ1_HUMAN
  • F4MHQ2_HUMAN
  • F4MHQ3_HUMAN
  • F4MHQ5_HUMAN
  • F4MHQ7_HUMAN
  • F4MHR0_HUMAN
  • F4MHR1_HUMAN
  • F4MHR2_HUMAN
  • F4MHR4_HUMAN
  • F4MHR5_HUMAN
  • F4MHR6_HUMAN
  • F4MHR7_HUMAN
  • F4MHR8_HUMAN
  • F4MHR9_HUMAN
  • F4MHS0_HUMAN
  • F4MHS1_HUMAN
  • F4MHS2_HUMAN
  • F4MHS3_HUMAN
  • F4MHS4_HUMAN
  • F4MHS5_HUMAN
  • F4MHS6_HUMAN
  • F4MHS7_HUMAN
  • F5GWV3_HUMAN
  • F5H3N7_HUMAN
  • F5H8B4_HUMAN
  • Q590G7_HUMAN
  • Q6IPS8_HUMAN
  • Q86UB8_HUMAN
  • Q9NR08_HUMAN
  • Q9P108_HUMAN
genes like me logo Genes that share paralogs with UTY: view

Variants for UTY Gene

Additional dbSNP identifiers (rs#s) for UTY Gene

Structural Variations from Database of Genomic Variants (DGV) for UTY Gene

Variant ID Type Subtype PubMed ID
nsv1141114 CNV deletion 24896259

Variation tolerance for UTY Gene

Gene Damage Index Score: 0.33; 7.25% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UTY Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UTY

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for UTY Gene

Disorders for UTY Gene

Additional Disease Information for UTY

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform

No disorders were found for UTY Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UTY Gene

Publications for UTY Gene

  1. The UTX gene escapes X inactivation in mice and humans. (PMID: 9499428) Greenfield A … Koopman P (Human molecular genetics 1998) 2 3 23
  2. Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase. (PMID: 24798337) Walport LJ … Johansson C (The Journal of biological chemistry 2014) 3 4
  3. Genetic variants of Y chromosome are associated with a protective lipid profile in black men. (PMID: 18511697) Russo P … Cappuccio FP (Arteriosclerosis, thrombosis, and vascular biology 2008) 3 41
  4. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PMID: 12665801) Gevaert K … Vandekerckhove J (Nature biotechnology 2003) 3 4
  5. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. (PMID: 12815422) Skaletsky H … Page DC (Nature 2003) 3 4

Products for UTY Gene

  • Signalway ELISA kits for UTY
  • Signalway Proteins for UTY

Sources for UTY Gene