Aliases for UTS2R Gene
External Ids for UTS2R Gene
Previous HGNC Symbols for UTS2R Gene
Previous GeneCards Identifiers for UTS2R Gene
GeneCards Summary for UTS2R Gene
UTS2R (Urotensin 2 Receptor) is a Protein Coding gene. Diseases associated with UTS2R include Pheochromocytoma and Rhabdomyosarcoma. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and urotensin II receptor activity. An important paralog of this gene is SSTR5.
UniProtKB/Swiss-Prot Summary for UTS2R Gene
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
The urotensin-II (UT) receptor is a Gq/11-protein-coupled receptor that mediates complex hemodynamic effects and influences neuromuscular physiology. The UT receptor displays greatest expression levels in the peripheral vasculature, heart and kidney.