Aliases for USP6NL Gene
External Ids for USP6NL Gene
Previous HGNC Symbols for USP6NL Gene
Previous GeneCards Identifiers for USP6NL Gene
GeneCards Summary for USP6NL Gene
USP6NL (USP6 N-Terminal Like) is a Protein Coding gene. Among its related pathways are Development EGFR signaling via small GTPases and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and Rab GTPase binding. An important paralog of this gene is TBC1D3K.
UniProtKB/Swiss-Prot Summary for USP6NL Gene
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.