Aliases for USP47 Gene
External Ids for USP47 Gene
Previous GeneCards Identifiers for USP47 Gene
GeneCards Summary for USP47 Gene
USP47 (Ubiquitin Specific Peptidase 47) is a Protein Coding gene. Among its related pathways are Deubiquitination and Ubiquitin-Proteasome Dependent Proteolysis. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase activity and thiol-dependent ubiquitinyl hydrolase activity. An important paralog of this gene is USP40.
UniProtKB/Swiss-Prot Summary for USP47 Gene
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.